Virtual Therapeutics for MCI (VR-MCI)
Mild Cognitive Impairment

About this trial
This is an interventional treatment trial for Mild Cognitive Impairment
Eligibility Criteria
Inclusion Criteria: a change in cognition recognized by patients or observers (Caregiver/examiner) an objective impairment in one or more cognitive domains using traditional neuropsychological tests; autonomy or slight dependence on daily life activities; absence of diagnosis of dementia absence of cognitive impairment measured by the mini-mental state examination; aged 65 or over Exclusion Criteria: the presence of acute stroke/transient ischemic attack occurred in the 6 months prior to the enrollment visit; the presence of aphasia and/or neglect; the presence of other concomitants severe neurological/psychiatric diseases (e.g., hemiparesis, multiple system atrophy, muscular skeletal/orthopedic deficits that limit movement) the presence of physical and/or functional deficits; the comorbidity with severe neurological and/or psychiatric diseases (e.g., neoplasms, multiple sclerosis, amyotrophic lateral sclerosis, Huntington's disease, schizophrenia, addiction, personality disorder, eating disorder) or with psychiatric conditions not under drug treatment (anxiety-depressive syndrome, bipolarism); the history of head trauma with loss of consciousness recurrent vertigo.
Sites / Locations
- Cosimo Tuena
Arms of the Study
Arm 1
Arm 2
Arm 3
Active Comparator
Experimental
Experimental
TAU
VR non-embodied
VR embodied
the treatment as usual (TAU; i.e., visuospatial "paper and pencil" stimulation) will consist of "paper and pencil" exercises used in clinical routine of 8 sessions of 30/40 minutes 3 times a week.
the non-embodied spatial training will consist of egocentric and allocentric spatial memory training with passive navigation of 8 sessions of 30/40 minutes 3 times a week.
the embodied spatial training will consist of egocentric and allocentric spatial memory training with active navigation of 8 sessions of 30/40 minutes 3 times a week.