Speech-in-noise Perception in Autism and Fragile X
Autism Spectrum Disorder, Fragile X Syndrome
About this trial
This is an interventional basic science trial for Autism Spectrum Disorder
Eligibility Criteria
Inclusion Criteria: normal audiograms (PTA ≤ 20 dB HL) corrected 20/20 vision (Snellen chart) no history of premature birth (prior to 36 weeks gestation) no medications known to affect EEG signal English as the first language Inclusion for the Autism group requires the following: 1) diagnosis of Autism Spectrum Disorder either based on previous ADOS administration and developmental history, or confirmed via ADOS and developmental history Inclusion for the Autism + FXS group requires the following: Documented PCR/Southern Blot genetic testing confirming full mutation FXS Diagnosis of Autism Spectrum Disorder, per Autism group. Inclusion for the Typically Developing group requires the following: no siblings or parents with an Autism Spectrum Disorder or Fragile X Syndrome no current neurological or psychiatric diagnoses IQ over 75 Exclusion Criteria: Hearing loss or uncorrected vision loss history of premature birth (prior to 36 weeks gestation)
Sites / Locations
Arms of the Study
Arm 1
Experimental
Speech Sounds
Participants will hear repeated speech sounds while wearing a neuroimaging cap.