Nebulization Versus Spray-as-You-Go Airway Topical Anesthesia Using Dexmedetomidine and Lidocaine Mixture During Awake Flexible Fiberoptic Intubation in Temporomandibular Ankylosis
Nebulization, Spray-as-You-Go, Dexmedetomidine
About this trial
This is an interventional treatment trial for Nebulization
Eligibility Criteria
Inclusion Criteria: Age from 21to 65 years. Both sexes. American Society of Anesthesiologists (ASA) physical status I or II and scheduled for elective surgery requiring general anesthesia , and known to have Temporomandibular joint ankylosis and expected to be difficult intubation patient due to restriction of jaw mobility and limited mouth opening less than 2 fingers. Exclusion Criteria: History of allergy to dexmedetomidine or lidocaine. History of drug abuse. Concomitant use of medications which may exaggerate the heart rate (HR) response of -dexmedetomidine (e.g. digoxin or β-adrenergic antagonists), HR <50 beats/min, systolic blood pressure (SBP) <90 mmHg. Pregnancy. Morbid obesity( BMI more than 35). Patients on anticoagulants, nasal trauma, deformity or polyp, CSF rhinorrhea, fracture base skull. Cardiac and/or respiratory disease, reactive airway disease, hepatic or renal disorders.
Sites / Locations
- Tanta UniversityRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Experimental
Group N (Nebulization group)
Group S (Spray-as-you-go)
Patients will receive a mixture of 2% lidocaine 10 ml and dexmedetomidine 1 μg/kg nebulization + saline 10 ml via spray-as-you-go technique.
Patients will receive a mixture of 2% lidocaine 10 ml and dexmedetomidine 1 μg/kg via spray-as-you-go technique + saline 10 ml nebulization.