A Chronic Pain Master Protocol (CPMP): A Study of LY3857210 in Participants With Diabetic Peripheral Neuropathic Pain (NP05)
Chronic Pain, Diabetic Peripheral Neuropathic Pain, Diabetic Peripheral Neuropathy
About this trial
This is an interventional treatment trial for Chronic Pain
Eligibility Criteria
Inclusion Criteria: Males and females may participate in this trial. No male contraception is required except in compliance with specific local government study requirements. Women of child bearing potential (WOCBP) and women not of child bearing potential (WNOCBP) may participate in this trial. Contraceptive use by participants should be consistent with local regulations regarding the methods of contraception for those participating in clinical studies. Exclusion Criteria: Have a seizure disorder, history of seizure (other than remote history of childhood febrile seizure), or a condition that would place the participant at increased risk of seizure, such as head injury (for example, skull fracture, cerebral contusion, concussion, or trauma resulting in prolonged unconsciousness), intracranial neoplasm or hemorrhage. Have an eGFR of <30 mL/min/1.73 m2, based on the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) formula at Day 1 or Day 2. evidence of Hepatitis B virus or Hepatitis C virus. Women who are pregnant or breastfeeding.
Sites / Locations
- Synexus Clinical Research US, Inc.
- Arizona Research Center
- Artemis Institute for Clinical Research
- Artemis Institute for Clinical Research
- CMR of Greater New Haven, LLC
- Accel Research Sites- Clinical Research Unit
- Suncoast Research Group
- University of Miami Don Suffer Clinical Research Building
- New Horizon Research Center
- Renstar Medical Research
- Synexus Clinical Research US, Inc - Orlando
- Synexus Clinical Research US, Inc.
- North Georgia Clinical Research
- Rocky Mountain Clinical Research
- Northwestern University
- Boston Clinical Trials
- ActivMed Practices and Research
- MedVadis Research Corporation
- Great Lakes Research Group, Inc.
- StudyMetrix Research
- Clinvest Headlands Llc
- Lillestol Research
- META Medical Research Institute
- Altoona center for clinical research
- FutureSearch Trials of Neurology
- Synexus Clinical Research - St. Petersburg
- Northwest Clinical Research Center
- Rainier Clinical Research Center
- Ponce Medical School Foundation Inc.
- Latin Clinical Trial Center
Arms of the Study
Arm 1
Arm 2
Experimental
Placebo Comparator
LY3857210
Placebo
Participants will be given LY3857210 orally.
Participants will be given placebo orally.