A Comparison of Two Tests for Anti-HIV Drug Resistance
HIV Infections
About this trial
This is an observational trial for HIV Infections focused on measuring HIV-1, Drug Resistance, Microbial, Sequence Analysis, DNA, Microbial Sensitivity Tests, Genotype, Phenotype, Anti-HIV Agents
Eligibility Criteria
Inclusion Criteria Patients may be eligible for this study if they: Are HIV-positive. Have failed 2 to 4 anti-HIV regimens containing 3 or more combinations of drugs. A patient has failed his/her current regimen if he/she has, within 30 days of study entry, either a viral load (level of HIV in the blood) of at least 10,000 copies/ml or 2 tests which show a viral load between 1,000 and 10,000 copies/ml. Have taken 3 or more anti-HIV drugs for 8 or more weeks before the study. Are at least 14 years old. Have consent of parent or guardian if less than 18 years old. Exclusion Criteria Patients will not be eligible for this study if they: Have failed only 1 anti-HIV drug combination. Have failed 5 or more anti-HIV drug combinations, each containing 3 to 5 drugs. Have had and received the results of prior resistance tests. Have had treatment with a combination of 6 or more anti-HIV drugs. Have problems absorbing food in the intestine. Have had HIV vaccines. Have taken drugs that affect the immune system or investigational drugs. Are taking medications not allowed with protease inhibitors (PIs) if PIs would be part of their anti-HIV treatment during the study. Have failed anti-HIV therapy due to nonadherence to medication.
Sites / Locations
- Univ of Alabama at Birmingham
- Univ of Southern California / LA County USC Med Ctr
- UCLA CARE Ctr
- Willow Clinic
- University of California San Francisco
- Univ of California San Francisco
- Santa Clara Valley Med Ctr / AIDS Community Rsch Consortium
- San Mateo AIDS Program / Stanford Univ
- Stanford Univ Med Ctr
- Harbor UCLA Med Ctr
- Denver Dept of Health and Hosps
- Univ of Colorado Health Sciences Ctr
- Univ of Miami School of Medicine
- Emory Univ
- Univ of Hawaii
- Northwestern Univ Med School
- Rush Presbyterian - Saint Luke's Med Ctr
- The CORE Ctr
- Johns Hopkins Hosp
- Harvard (Massachusetts Gen Hosp)
- Beth Israel Deaconess - West Campus
- Brigham and Women's Hosp
- SUNY / Erie County Med Ctr at Buffalo
- Beth Israel Med Ctr
- Cornell Clinical Trials Unit - Chelsea Clinic
- Bellevue Hosp / New York Univ Med Ctr
- Cornell Univ Med Ctr
- Mount Sinai Med Ctr
- Columbia Presbyterian Med Ctr
- Univ of North Carolina
- Carolinas Med Ctr
- Duke Univ Med Ctr
- Moses H Cone Memorial Hosp
- Univ of Cincinnati
- Case Western Reserve Univ
- MetroHealth Med Ctr
- Ohio State Univ Hosp Clinic
- Philadelphia Veterans Administration Med Ctr
- Univ of Pennsylvania
- Univ of Pittsburgh
- Brown Univ / Miriam Hosp
- Miriam Hosp / Brown Univ
- Julio Arroyo
- Vanderbilt Univ Med Ctr
- Univ of Texas, Southwestern Med Ctr of Dallas
- Univ of Washington
- Univ of Puerto Rico