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A Comparison of Weighted Vest Exercise and Strength Training

Primary Purpose

Mobility Limitations, Aging

Status
Completed
Phase
Phase 3
Locations
United States
Study Type
Interventional
Intervention
InVEST (Increased Velocity Exercise Specific to Task)
Sponsored by
National Institute on Aging (NIA)
About
Eligibility
Locations
Outcomes
Full info

About this trial

This is an interventional treatment trial for Mobility Limitations focused on measuring strength training, power training, exercise training, functional performance tasks

Eligibility Criteria

65 Years - undefined (Older Adult)All SexesDoes not accept healthy volunteers

Inclusion Criteria: Community dwelling men and women aged 65 or older Ability to provide informed consent Impairment in physical performance, based on a score between 4 and 10 inclusive on the SPPB (Short Physical Performance Battery), which evaluates standing balance, walking speed, and chair-rise time Score of 24 or greater on the Folstein mini-mental status exam Exhibit independent stair-climbing ability Exclusion Criteria: Unstable acute or chronic disease Neuromusculoskeletal impairment interfering with independent stair climbing Abdominal aortic aneurysm Exertional angina History of ventricular arrhythmia Inguinal or abdominal hernia Symptomatic valvular heart disease

Sites / Locations

  • Spaulding Cambridge Outpatient Center

Outcomes

Primary Outcome Measures

Leg power
leg strength
mobility
endurance
balance measured at baseline, 8 weeks, and 16 weeks

Secondary Outcome Measures

Disability

Full Information

First Posted
September 7, 2005
Last Updated
July 23, 2010
Sponsor
National Institute on Aging (NIA)
Collaborators
Spaulding Rehabilitation Hospital PM&R
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1. Study Identification

Unique Protocol Identification Number
NCT00158119
Brief Title
A Comparison of Weighted Vest Exercise and Strength Training
Official Title
Ameliorating Disability Through Power Training
Study Type
Interventional

2. Study Status

Record Verification Date
July 2010
Overall Recruitment Status
Completed
Study Start Date
July 2001 (undefined)
Primary Completion Date
September 2007 (Actual)
Study Completion Date
September 2007 (Actual)

3. Sponsor/Collaborators

Name of the Sponsor
National Institute on Aging (NIA)
Collaborators
Spaulding Rehabilitation Hospital PM&R

4. Oversight

5. Study Description

Brief Summary
The purpose of this study is to evaluate two types of exercise therapy designed to improve muscle power and mobility: weighted vest exercise vs. progressive resistance training.
Detailed Description
Muscle power, a separate physical attribute from strength, is an important determinate of physical functioning in the elderly, for example in avoiding impending falls, rising from a chair, and climbing stairs. Muscle power, which declines with aging at a different rate than strength, has been shown in previous studies to improve through power training utilizing specially designed exercise equipment. However, weighted vest exercise could provide an acceptable, low cost, readily accessible alternative. The hypotheses being tested in this study are: 1) weighted vest exercise will improve lower extremity power when compared to age matched controls in a standardized progressive resistance training program; 2) improvements in lower extremity power enhance functional performance as shown by improved gait velocity, stair climbing, and chair rise time; and 3) weighted vest exercise in impaired older adults will improve self-reported function and disability. One hundred sixty-four men and women ages 65 and older, with some physical limitation but able to climb stairs independently, will be randomized to one of two 16-week exercise programs. The intervention group will participate in a weighted vest exercise protocol, consisting of chair-based and stair-climbing exercise, while the control group will participate in a standardized progressive resistance training program. Participants in both programs will meet three times per week for 30-60 minutes per session, for a total of 16 weeks, at a research exercise gym, and will be under the direct supervision of research staff.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Mobility Limitations, Aging
Keywords
strength training, power training, exercise training, functional performance tasks

7. Study Design

Primary Purpose
Treatment
Study Phase
Phase 3
Interventional Study Model
Parallel Assignment
Masking
Single
Allocation
Randomized
Enrollment
160 (false)

8. Arms, Groups, and Interventions

Intervention Type
Behavioral
Intervention Name(s)
InVEST (Increased Velocity Exercise Specific to Task)
Primary Outcome Measure Information:
Title
Leg power
Title
leg strength
Title
mobility
Title
endurance
Title
balance measured at baseline, 8 weeks, and 16 weeks
Secondary Outcome Measure Information:
Title
Disability

10. Eligibility

Sex
All
Minimum Age & Unit of Time
65 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria: Community dwelling men and women aged 65 or older Ability to provide informed consent Impairment in physical performance, based on a score between 4 and 10 inclusive on the SPPB (Short Physical Performance Battery), which evaluates standing balance, walking speed, and chair-rise time Score of 24 or greater on the Folstein mini-mental status exam Exhibit independent stair-climbing ability Exclusion Criteria: Unstable acute or chronic disease Neuromusculoskeletal impairment interfering with independent stair climbing Abdominal aortic aneurysm Exertional angina History of ventricular arrhythmia Inguinal or abdominal hernia Symptomatic valvular heart disease
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Jonathan F. Bean, MD, MS
Organizational Affiliation
Spaulding Cambridge Outpatient Center
Official's Role
Principal Investigator
Facility Information:
Facility Name
Spaulding Cambridge Outpatient Center
City
Cambridge
State/Province
Massachusetts
ZIP/Postal Code
02138
Country
United States

12. IPD Sharing Statement

Citations:
PubMed Identifier
11943041
Citation
Bean JF, Kiely DK, Herman S, Leveille SG, Mizer K, Frontera WR, Fielding RA. The relationship between leg power and physical performance in mobility-limited older people. J Am Geriatr Soc. 2002 Mar;50(3):461-7. doi: 10.1046/j.1532-5415.2002.50111.x.
Results Reference
background
PubMed Identifier
11982666
Citation
Bean J, Herman S, Kiely DK, Callahan D, Mizer K, Frontera WR, Fielding RA. Weighted stair climbing in mobility-limited older people: a pilot study. J Am Geriatr Soc. 2002 Apr;50(4):663-70. doi: 10.1046/j.1532-5415.2002.50160.x.
Results Reference
background
PubMed Identifier
11982665
Citation
Fielding RA, LeBrasseur NK, Cuoco A, Bean J, Mizer K, Fiatarone Singh MA. High-velocity resistance training increases skeletal muscle peak power in older women. J Am Geriatr Soc. 2002 Apr;50(4):655-62. doi: 10.1046/j.1532-5415.2002.50159.x.
Results Reference
background
PubMed Identifier
15086665
Citation
Bean JF, Herman S, Kiely DK, Frey IC, Leveille SG, Fielding RA, Frontera WR. Increased Velocity Exercise Specific to Task (InVEST) training: a pilot study exploring effects on leg power, balance, and mobility in community-dwelling older women. J Am Geriatr Soc. 2004 May;52(5):799-804. doi: 10.1111/j.1532-5415.2004.52222.x.
Results Reference
background
PubMed Identifier
15221722
Citation
Bean JF, Vora A, Frontera WR. Benefits of exercise for community-dwelling older adults. Arch Phys Med Rehabil. 2004 Jul;85(7 Suppl 3):S31-42; quiz S43-4. doi: 10.1016/j.apmr.2004.03.010.
Results Reference
background
PubMed Identifier
22289248
Citation
Li X, Forman DE, Kiely DK, LaRose S, Hirschberg R, Frontera WR, Bean JF. Validity of an exercise test based on habitual gait speed in mobility-limited older adults. Arch Phys Med Rehabil. 2012 Feb;93(2):344-50. doi: 10.1016/j.apmr.2011.08.032.
Results Reference
derived
PubMed Identifier
21636073
Citation
Suri P, Kiely DK, Leveille SG, Frontera WR, Bean JF. Increased trunk extension endurance is associated with meaningful improvement in balance among older adults with mobility problems. Arch Phys Med Rehabil. 2011 Jul;92(7):1038-43. doi: 10.1016/j.apmr.2010.12.044. Epub 2011 Jun 2.
Results Reference
derived
PubMed Identifier
21143443
Citation
Bean JF, Kiely DK, LaRose S, Goldstein R, Frontera WR, Leveille SG. Are changes in leg power responsible for clinically meaningful improvements in mobility in older adults? J Am Geriatr Soc. 2010 Dec;58(12):2363-8. doi: 10.1111/j.1532-5415.2010.03155.x.
Results Reference
derived
PubMed Identifier
19854420
Citation
Suri P, Kiely DK, Leveille SG, Frontera WR, Bean JF. Trunk muscle attributes are associated with balance and mobility in older adults: a pilot study. PM R. 2009 Oct;1(10):916-24. doi: 10.1016/j.pmrj.2009.09.009.
Results Reference
derived
PubMed Identifier
19414509
Citation
Bean JF, Kiely DK, LaRose S, O'Neill E, Goldstein R, Frontera WR. Increased velocity exercise specific to task training versus the National Institute on Aging's strength training program: changes in limb power and mobility. J Gerontol A Biol Sci Med Sci. 2009 Sep;64(9):983-91. doi: 10.1093/gerona/glp056. Epub 2009 May 4.
Results Reference
derived

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A Comparison of Weighted Vest Exercise and Strength Training

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