A Modified Cuff Leak Test and Reintubation in Mechanically Ventilated Patients
Mechanical Ventilation Complication, Weaning Failure, Airway Obstruction
About this trial
This is an interventional prevention trial for Mechanical Ventilation Complication
Eligibility Criteria
Inclusion Criteria:
- Age ≥ 18 years old
- Oral endotracheal intubation and mechanical ventilation > 36 hours
- Fulfilled the weaning criteria
Exclusion Criteria:
- The patient has a chest drainage tube and there is persistent air leak
- Abnormalities of the larynx: such as tumors or vocal cord paralysis
- The patient cannot maintain the semi-recumbent position
- Unconventional weaning, such as awake ECMO, etc
- Participated in the study during the hospitalization
- Patients or their relatives refused written informed consent
Sites / Locations
- Bing SunRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Modified Cuff Leak Test
Usual Cuff Leak Test
The subject was placed in a semi-recumbent position. The subjects were placed in volume assist-control mode with the following parameters: respiratory rate 15 breaths/min original oxygen concentration PEEP 0 cm H2O the VT was set according to the subject's stable VT in the previous ventilator mode inspiratory flow was set at 30 L/min with square waveform Positive cutoff value of the air leak volume was 116 mL and the air leak ratio was 0.32.
The subjects were placed in volume assist-control mode with the following parameters: respiratory rate was adapted to patient comfort original oxygen concentration and PEEP the VT about 8ml/Kg IBW inspiratory flow was set at 60 L/min with square waveform Positive cutoff value of the air leak volume was 110 mL and the air leak ratio was 0.15.