A Multicentre Trial to Determine the Efficacy of AD 452 in RA Subjects.
Rheumatoid Arthritis
About this trial
This is an interventional treatment trial for Rheumatoid Arthritis focused on measuring Rheumatoid Arthritis, RA, ACR20 endpoint, Tender/swollen joints, Improvement in pain, Health assessment questionnaire, Profile of mood states
Eligibility Criteria
Inclusion Criteria: Male/female age 18 -75 RA diagnosed for at least 6 months Taking methotrexate for at least 6 months Must have at least 4 swollen/tender joints Exclusion Criteria: Must not be pregnant/breastfeeding Must not have history of other inflammatory disorders Other conditions may lead to exclusion from the trial (e.g. Diabetes mellitus, malignant melanoma, HIV, active infection, hepatitis B/C, cardiac conduction disorders, hepatic/renal insufficiency, active depression/anxiety/psychosis/schizophrenia or convulsions.
Sites / Locations
- Clinical Research of West Florida, Inc
- Center for Rheumatology, Immunology and Arthritis
- Ocala Rheumatology Research Center
- Sarasota Arthritis Research Center
- Advent Clinical Research Centers, Inc.
- Dept of Rheumatology, Columbia Medical Practice
- Anderson and Collins Clinical Research, Inc.
- Station Avenue
- Atlantic Coast Research LLC
- Rheumatic Disease Associates