Back to resultsA Phase 2 Study to Evaluate Efficacy and Safety of AL002 in Participants With Early Alzheimer's Disease (INVOKE-2)
Primary Purpose
Alzheimer Disease
Status
Active
Phase
Phase 2
Locations
International
Study Type
Interventional
Intervention
AL002
Placebo
Sponsored by
About this trial
This is an interventional treatment trial for Alzheimer Disease
Eligibility Criteria
Inclusion Criteria:
- Diagnosis of Early AD including evidence of brain amyloidosis by CSF or PET
- MMSE score ≥ 22 points, CDR Global Score of 0.5 - 1.0, and RBANS score on the DMI ≤85.
- Study partner who consents to study participation and who cares for/visits the participant at least 10 hours a week
- Written informed consent must be obtained and documented (from the participant or, where jurisdictions allow it, from their legal decision maker).
Exclusion Criteria:
- Dementia due to a condition other than AD including, but not limited to, FTD, Parkinson's disease, dementia with Lewy bodies, Huntington disease, or vascular dementia.
- Known history of severe allergic, anaphylactic, or other hypersensitivity reactions to chimeric, human, or humanized antibodies or fusion proteins.
- Current uncontrolled hypertension, diabetes mellitus or thyroid disease. Clinically significant heart disease, liver disease or kidney disease.
- History or evidence of clinically significant brain disease other than AD.
- Females who are pregnant or breastfeeding, or planning to conceive within the study period.
- Any experimental vaccine or gene therapy.
- History of unresolved cancer.
- Current use of anticoagulant medications.
- Residence in a skilled nursing facility, convalescent home, or long term care facility at screening; or requires continuous nursing care.
Sites / Locations
- Banner Alzheimer's Institute
- Woodlands Research Network, LLC - ERG
- ATP Clinical Research
- Irvine Center For Clinical Research
- Stanford University
- Syrentis Cinical Research
- Georgetown University Medical Center
- South Florida Neurology Associates
- Brain Matters Research - ERG
- Charter Research
- ClinCloud, LLC
- K2 Medical Research
- Suncoast Clinical Research, Inc
- K2 Winter Garden Ocoee
- Progressive Medical Research
- Axiom Clinical Research FL
- K2 The Villages
- Alzheimers Research and Treatment Center
- Conquest Clinical Research (Winter Park)
- Emory University
- AMITA Health Clinical Research Institute
- University of Kentucky
- Boston Center for Memory
- Hattiesburg Clinic
- Advanced Clinical Institute
- Feinstein Institute For MR
- Columbia University College of Physicians and Surgeons
- University of Rochester Medical Center
- SUNY Upstate Medical Center
- University of Cincinnati MC
- Summit Research Network
- Center for Cognitive Health
- Abington Neurologic Associates
- Keystone Clinical Studies LLC
- Clinical Trial Network
- University of Texas - San Antonio
- Instituto Kremer
- Centro de Psiquiatría Biológica Instituto Senecta
- KaRa Institute of Neurological Disease
- Box Hill Hospital
- The Alfred Hospital
- SMarT Minds WA
- Okanagan Clinical Trials
- True North Clinical Research - Halifax
- True North Clinical Research - New Minas
- Parkwood Institute
- Bruyère Research Institute
- Kawartha Regional Memory Clinic
- Toronto Memory Clinic
- Baycrest Health Sciences
- Hopitaux de La Timone
- Hôpital Roger Salengro
- Hopital Lariboisiere
- Hôpital de la Pitié Salpétrière
- Centre Hospitalier Universitaire de Toulouse
- Gerontopole
- Charité - Universitätsmedizin Berlin (CBF)
- Charite Campus Buch
- University Clinic Heidelberg
- LMU Klinikum der Universität München
- Klinikum rechts der Isa der Technischen Universitaet Muenchen
- Universitätsklinikum Ulm
- Fondazione Policlinico Universitario A Gemelli
- Azienda Policlinico Umberto I
- Ospedale S Giovanni Calibita Fatebenefratelli
- IRCCS - Centro S. Giovanni di Dio Fatebenefratelli
- ASST degli Spedali Civili di Brescia - Spedali Civili di Brescia
- Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico
- Fondazione IRCCS Di Rilievo Nazionale Istituto Nazionale Neurologico Carlo Besta
- Ospedale Civile di Baggiovara
- Azienda Ospedaliero Universitaria Pisana
- Ospedale degli Infermi
- Brain Research Center Den Bosch
- Brain Research Center Amsterdam
- CGM Research Trust
- NZOZ Wroclawskie Centrum Alzheimerowskie
- Centrum Medyczne NeuroProtect
- Podlaskie Centrum Psychogeriatrii
- Wielospecjalistyczna Poradnia Lekarska Synapsis
- EUROMEDIS Sp. z o.o.
- SOMED CR
- Hospital de La Santa Creu i Sant Pau
- Fundacion CITA Alzheimer Fundazioa
- Centro de Atencion Especializada Oroitu
- Fundacion ACE Instituto Catalan de Neurociencias
- Hospital Clinic de Barcelona
- Hospital Universitario Ramon y Cajal
- Hospital Universitario Doctor Peset
- Hospital Universitari i Politecnic La Fe de Valencia
- Hospital Viamed Montecanal
- Re: Cognition Health - Guildford
- Re:Cognition Health Bristol
- Re:Cognition Health London
- The National Hospital for Neurology and Neurosurgery
- Greater Manchester Mental Health NHS Foundation Trust
- Glasgow Memory Clinic
- Re:Cognition Health Plymouth
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Arm Type
Experimental
Experimental
Experimental
Placebo Comparator
Arm Label
AL002 Dose 1
AL002 Dose 2
AL002 Dose 3
Placebo
Arm Description
AL002 every 4 weeks
AL002 every 4 weeks
AL002 every 4 weeks
Placebo every 4 weeks
Outcomes
Primary Outcome Measures
Disease progression as measured by the CDR-SB
Secondary Outcome Measures
Change in MMSE score
Change in RBANS score
Change in ADAS-Cog13 score
Change in ADCS-ADL-MCI score
Change in ADCOMS score
Evaluation of safety and tolerability of AL002: Incidence of adverse events
Incidence of adverse events
Full Information
NCT ID
NCT04592874
First Posted
September 17, 2020
Last Updated
September 5, 2023
Sponsor
Alector Inc.
Collaborators
AbbVie
1. Study Identification
Unique Protocol Identification Number
NCT04592874
Brief Title
A Phase 2 Study to Evaluate Efficacy and Safety of AL002 in Participants With Early Alzheimer's Disease
Acronym
INVOKE-2
Official Title
A Phase 2 Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate the Efficacy and Safety of AL002 in Participants With Early Alzheimer's Disease
Study Type
Interventional
2. Study Status
Record Verification Date
September 2023
Overall Recruitment Status
Active, not recruiting
Study Start Date
January 22, 2021 (Actual)
Primary Completion Date
October 3, 2024 (Anticipated)
Study Completion Date
November 11, 2024 (Anticipated)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Sponsor
Name of the Sponsor
Alector Inc.
Collaborators
AbbVie
4. Oversight
Studies a U.S. FDA-regulated Drug Product
Yes
Studies a U.S. FDA-regulated Device Product
No
Data Monitoring Committee
Yes
5. Study Description
Brief Summary
A phase 2 randomized, double blind, placebo controlled study evaluating the efficacy and safety of AL002 in participants with Early Alzheimer's Disease.
Detailed Description
This is a phase 2 randomized, double blind, placebo controlled study evaluating the efficacy and safety of AL002 administered intravenously in participants with Early Alzheimer's Disease.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Alzheimer Disease
7. Study Design
Primary Purpose
Treatment
Study Phase
Phase 2
Interventional Study Model
Parallel Assignment
Masking
ParticipantCare ProviderInvestigatorOutcomes Assessor
Allocation
Randomized
Enrollment
328 (Anticipated)
8. Arms, Groups, and Interventions
Arm Title
AL002 Dose 1
Arm Type
Experimental
Arm Description
AL002 every 4 weeks
Arm Title
AL002 Dose 2
Arm Type
Experimental
Arm Description
AL002 every 4 weeks
Arm Title
AL002 Dose 3
Arm Type
Experimental
Arm Description
AL002 every 4 weeks
Arm Title
Placebo
Arm Type
Placebo Comparator
Arm Description
Placebo every 4 weeks
Intervention Type
Drug
Intervention Name(s)
AL002
Intervention Description
Administered via intravenous (IV) infusion
Intervention Type
Drug
Intervention Name(s)
Placebo
Intervention Description
Administered via intravenous (IV) infusion
Primary Outcome Measure Information:
Title
Disease progression as measured by the CDR-SB
Time Frame
Through study completion, up to 48 through 96 weeks
Secondary Outcome Measure Information:
Title
Change in MMSE score
Time Frame
Through study completion, up to 48 through 96 weeks
Title
Change in RBANS score
Time Frame
Through study completion, up to 48 through 96 weeks
Title
Change in ADAS-Cog13 score
Time Frame
Through study completion, up to 48 through 96 weeks
Title
Change in ADCS-ADL-MCI score
Time Frame
Through study completion, up to 48 through 96 weeks
Title
Change in ADCOMS score
Time Frame
Through study completion, up to 48 through 96 weeks
Title
Evaluation of safety and tolerability of AL002: Incidence of adverse events
Description
Incidence of adverse events
Time Frame
Through study completion, up to 48 through 96 weeks
Other Pre-specified Outcome Measures:
Title
Change in brain volume as assessed by magnetic resonance imaging
Time Frame
Through study completion, up to 48 through 96 weeks
Title
Change in blood based biomarkers
Time Frame
Through study completion, up to 48 through 96 weeks
Title
Change in CSF biomarkers (optional)
Time Frame
Through study completion, up to 48 through 96 weeks
Title
Change in amyloid burden as assessed by positron emission tomography imaging (optional)
Time Frame
Through study completion, up to 48 through 96 weeks
Title
Change in tau tangles as assessed by positron emission tomography imaging (optional)
Time Frame
Through study completion, up to 48 through 96 weeks
Title
Change in Winterlight Language Speech Assessment score (optional)
Time Frame
Through study completion, up to 48 through 96 weeks
10. Eligibility
Sex
All
Minimum Age & Unit of Time
50 Years
Maximum Age & Unit of Time
85 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria:
Diagnosis of Early AD including evidence of brain amyloidosis by CSF or PET
MMSE score ≥ 20 points, CDR Global Score of 0.5 - 1.0, and RBANS score on the DMI ≤95.
Study partner who consents to study participation and who cares for/visits the participant at least 10 hours a week
Written informed consent must be obtained and documented (from the participant or, where jurisdictions allow it, from their legal decision maker).
Exclusion Criteria:
Dementia due to a condition other than AD including, but not limited to, FTD, Parkinson's disease, dementia with Lewy bodies, Huntington disease, or vascular dementia. - Dementia due to a condition other than AD including, but not limited to, FTD, Parkinson's disease, dementia with Lewy bodies, Huntington disease, or vascular dementia.
Known history of severe allergic, anaphylactic, or other hypersensitivity reactions to chimeric, human, or humanized antibodies or fusion proteins.
Current uncontrolled hypertension, diabetes mellitus or thyroid disease. Clinically significant heart disease, liver disease or kidney disease.
History or evidence of clinically significant brain disease other than AD.
Females who are pregnant or breastfeeding, or planning to conceive within the study period.
Any experimental vaccine or gene therapy.
History of unresolved cancer.
Current use of anticoagulant medications.
Residence in a skilled nursing facility, convalescent home, or long term care facility at screening; or requires continuous nursing care.
Participant is positive for presence of APOE e4/e4 genotype.
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
TBD TBD
Official's Role
Principal Investigator
Facility Information:
Facility Name
Banner Alzheimer's Institute
City
Phoenix
State/Province
Arizona
ZIP/Postal Code
85006
Country
United States
Facility Name
Woodlands Research Network, LLC - ERG
City
Rogers
State/Province
Arkansas
ZIP/Postal Code
72758
Country
United States
Facility Name
ATP Clinical Research
City
Costa Mesa
State/Province
California
ZIP/Postal Code
92626
Country
United States
Facility Name
Irvine Center For Clinical Research
City
Irvine
State/Province
California
ZIP/Postal Code
92614-9403
Country
United States
Facility Name
Stanford University
City
Palo Alto
State/Province
California
ZIP/Postal Code
94304
Country
United States
Facility Name
Syrentis Cinical Research
City
Santa Ana
State/Province
California
ZIP/Postal Code
92705
Country
United States
Facility Name
Georgetown University Medical Center
City
Washington
State/Province
District of Columbia
ZIP/Postal Code
20007
Country
United States
Facility Name
South Florida Neurology Associates
City
Boca Raton
State/Province
Florida
ZIP/Postal Code
33487
Country
United States
Facility Name
Brain Matters Research - ERG
City
Delray Beach
State/Province
Florida
ZIP/Postal Code
33445
Country
United States
Facility Name
Charter Research
City
Lady Lake
State/Province
Florida
ZIP/Postal Code
32159
Country
United States
Facility Name
ClinCloud, LLC
City
Maitland
State/Province
Florida
ZIP/Postal Code
32751
Country
United States
Facility Name
K2 Medical Research
City
Maitland
State/Province
Florida
ZIP/Postal Code
32751
Country
United States
Facility Name
Suncoast Clinical Research, Inc
City
New Port Richey
State/Province
Florida
ZIP/Postal Code
34652
Country
United States
Facility Name
K2 Winter Garden Ocoee
City
Ocoee
State/Province
Florida
ZIP/Postal Code
34761
Country
United States
Facility Name
Progressive Medical Research
City
Port Orange
State/Province
Florida
ZIP/Postal Code
32127-5170
Country
United States
Facility Name
Axiom Clinical Research FL
City
Tampa
State/Province
Florida
ZIP/Postal Code
33609
Country
United States
Facility Name
K2 The Villages
City
The Villages
State/Province
Florida
ZIP/Postal Code
32159
Country
United States
Facility Name
Alzheimers Research and Treatment Center
City
Wellington
State/Province
Florida
ZIP/Postal Code
33449
Country
United States
Facility Name
Conquest Clinical Research (Winter Park)
City
Winter Park
State/Province
Florida
ZIP/Postal Code
32789
Country
United States
Facility Name
Emory University
City
Atlanta
State/Province
Georgia
ZIP/Postal Code
30322
Country
United States
Facility Name
AMITA Health Clinical Research Institute
City
Elk Grove Village
State/Province
Illinois
ZIP/Postal Code
60007
Country
United States
Facility Name
University of Kentucky
City
Lexington
State/Province
Kentucky
ZIP/Postal Code
40536
Country
United States
Facility Name
Boston Center for Memory
City
Newton
State/Province
Massachusetts
ZIP/Postal Code
02459
Country
United States
Facility Name
Hattiesburg Clinic
City
Hattiesburg
State/Province
Mississippi
ZIP/Postal Code
39401
Country
United States
Facility Name
Advanced Clinical Institute
City
Neptune
State/Province
New Jersey
ZIP/Postal Code
07753
Country
United States
Facility Name
Feinstein Institute For MR
City
Manhasset
State/Province
New York
ZIP/Postal Code
11030
Country
United States
Facility Name
Columbia University College of Physicians and Surgeons
City
New York
State/Province
New York
ZIP/Postal Code
10032-3725
Country
United States
Facility Name
University of Rochester Medical Center
City
Rochester
State/Province
New York
ZIP/Postal Code
14620
Country
United States
Facility Name
SUNY Upstate Medical Center
City
Syracuse
State/Province
New York
ZIP/Postal Code
13210
Country
United States
Facility Name
University of Cincinnati MC
City
Cincinnati
State/Province
Ohio
ZIP/Postal Code
45219
Country
United States
Facility Name
Summit Research Network
City
Portland
State/Province
Oregon
ZIP/Postal Code
97210
Country
United States
Facility Name
Center for Cognitive Health
City
Portland
State/Province
Oregon
ZIP/Postal Code
97225-5031
Country
United States
Facility Name
Abington Neurologic Associates
City
Abington
State/Province
Pennsylvania
ZIP/Postal Code
19090
Country
United States
Facility Name
Keystone Clinical Studies LLC
City
Plymouth Meeting
State/Province
Pennsylvania
ZIP/Postal Code
19462-7401
Country
United States
Facility Name
Clinical Trial Network
City
Houston
State/Province
Texas
ZIP/Postal Code
77074-2085
Country
United States
Facility Name
University of Texas - San Antonio
City
San Antonio
State/Province
Texas
ZIP/Postal Code
78259
Country
United States
Facility Name
Instituto Kremer
City
Córdoba
ZIP/Postal Code
X5004AOA
Country
Argentina
Facility Name
Centro de Psiquiatría Biológica Instituto Senecta
City
Mendoza
ZIP/Postal Code
5500
Country
Argentina
Facility Name
KaRa Institute of Neurological Disease
City
Macquarie Park
State/Province
New South Wales
ZIP/Postal Code
2113
Country
Australia
Facility Name
Box Hill Hospital
City
Box Hill
State/Province
Victoria
ZIP/Postal Code
3128
Country
Australia
Facility Name
The Alfred Hospital
City
Parkville
State/Province
Victoria
ZIP/Postal Code
3050
Country
Australia
Facility Name
SMarT Minds WA
City
Nedlands
State/Province
Western Australia
ZIP/Postal Code
6009
Country
Australia
Facility Name
Okanagan Clinical Trials
City
Kelowna
State/Province
British Columbia
ZIP/Postal Code
V1Y 1Z9
Country
Canada
Facility Name
True North Clinical Research - Halifax
City
Halifax
State/Province
Nova Scotia
ZIP/Postal Code
B3S 1N2
Country
Canada
Facility Name
True North Clinical Research - New Minas
City
New Minas
State/Province
Nova Scotia
ZIP/Postal Code
B4N 3R7
Country
Canada
Facility Name
Parkwood Institute
City
London
State/Province
Ontario
ZIP/Postal Code
N6C 0A7
Country
Canada
Facility Name
Bruyère Research Institute
City
Ottawa
State/Province
Ontario
ZIP/Postal Code
K1N 5C8
Country
Canada
Facility Name
Kawartha Regional Memory Clinic
City
Peterborough
State/Province
Ontario
ZIP/Postal Code
K9H 2P4
Country
Canada
Facility Name
Toronto Memory Clinic
City
Toronto
State/Province
Ontario
ZIP/Postal Code
M3B 2S7
Country
Canada
Facility Name
Baycrest Health Sciences
City
Toronto
State/Province
Ontario
ZIP/Postal Code
Ontario
Country
Canada
Facility Name
Hopitaux de La Timone
City
Marseille
State/Province
Bouches-du-Rhône
ZIP/Postal Code
13385
Country
France
Facility Name
Hôpital Roger Salengro
City
Lille
State/Province
Nord
ZIP/Postal Code
59037
Country
France
Facility Name
Hopital Lariboisiere
City
Paris
ZIP/Postal Code
75010
Country
France
Facility Name
Hôpital de la Pitié Salpétrière
City
Paris
ZIP/Postal Code
75013
Country
France
Facility Name
Centre Hospitalier Universitaire de Toulouse
City
Toulouse
ZIP/Postal Code
31059
Country
France
Facility Name
Gerontopole
City
Toulouse
ZIP/Postal Code
31059
Country
France
Facility Name
Charité - Universitätsmedizin Berlin (CBF)
City
Berlin
ZIP/Postal Code
12203
Country
Germany
Facility Name
Charite Campus Buch
City
Berlin
ZIP/Postal Code
13125
Country
Germany
Facility Name
University Clinic Heidelberg
City
Mannheim
ZIP/Postal Code
68159
Country
Germany
Facility Name
LMU Klinikum der Universität München
City
München
ZIP/Postal Code
81377
Country
Germany
Facility Name
Klinikum rechts der Isa der Technischen Universitaet Muenchen
City
München
ZIP/Postal Code
81675
Country
Germany
Facility Name
Universitätsklinikum Ulm
City
Ulm
ZIP/Postal Code
89081
Country
Germany
Facility Name
Fondazione Policlinico Universitario A Gemelli
City
Roma
State/Province
Lazio
ZIP/Postal Code
00168
Country
Italy
Facility Name
Azienda Policlinico Umberto I
City
Roma
State/Province
Lazio
ZIP/Postal Code
00185
Country
Italy
Facility Name
Ospedale S Giovanni Calibita Fatebenefratelli
City
Roma
State/Province
Lazio
ZIP/Postal Code
00186
Country
Italy
Facility Name
IRCCS - Centro S. Giovanni di Dio Fatebenefratelli
City
Brescia
State/Province
Lombardia
ZIP/Postal Code
25125
Country
Italy
Facility Name
ASST degli Spedali Civili di Brescia - Spedali Civili di Brescia
City
Brescia
ZIP/Postal Code
25123
Country
Italy
Facility Name
Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico
City
Milano
ZIP/Postal Code
20122
Country
Italy
Facility Name
Fondazione IRCCS Di Rilievo Nazionale Istituto Nazionale Neurologico Carlo Besta
City
Milano
ZIP/Postal Code
20133
Country
Italy
Facility Name
Ospedale Civile di Baggiovara
City
Modena
ZIP/Postal Code
41126
Country
Italy
Facility Name
Azienda Ospedaliero Universitaria Pisana
City
Pisa
ZIP/Postal Code
56126
Country
Italy
Facility Name
Ospedale degli Infermi
City
Ponderano
ZIP/Postal Code
13875
Country
Italy
Facility Name
Brain Research Center Den Bosch
City
's-Hertogenbosch
State/Province
Noord-Brabant
ZIP/Postal Code
5223 GV
Country
Netherlands
Facility Name
Brain Research Center Amsterdam
City
Amsterdam
ZIP/Postal Code
1081 GN
Country
Netherlands
Facility Name
CGM Research Trust
City
Christchurch
ZIP/Postal Code
8083
Country
New Zealand
Facility Name
NZOZ Wroclawskie Centrum Alzheimerowskie
City
Wrocław
State/Province
Dolnoslaskie
ZIP/Postal Code
53-110
Country
Poland
Facility Name
Centrum Medyczne NeuroProtect
City
Warszawa
State/Province
Mazowieckie
ZIP/Postal Code
01-684
Country
Poland
Facility Name
Podlaskie Centrum Psychogeriatrii
City
Białystok
State/Province
Podlaskie
ZIP/Postal Code
15-756
Country
Poland
Facility Name
Wielospecjalistyczna Poradnia Lekarska Synapsis
City
Katowice
State/Province
Slaskie
ZIP/Postal Code
40-123
Country
Poland
Facility Name
EUROMEDIS Sp. z o.o.
City
Szczecin
State/Province
Zachodniopomorskie
ZIP/Postal Code
70-111
Country
Poland
Facility Name
SOMED CR
City
Warsaw
ZIP/Postal Code
01-737
Country
Poland
Facility Name
Hospital de La Santa Creu i Sant Pau
City
Barcelona
State/Province
Cataluña
ZIP/Postal Code
08041
Country
Spain
Facility Name
Fundacion CITA Alzheimer Fundazioa
City
Donostia
State/Province
Guipuzcoa
ZIP/Postal Code
20009
Country
Spain
Facility Name
Centro de Atencion Especializada Oroitu
City
Getxo
State/Province
Pais Vasco
ZIP/Postal Code
48993
Country
Spain
Facility Name
Fundacion ACE Instituto Catalan de Neurociencias
City
Barcelona
ZIP/Postal Code
08028
Country
Spain
Facility Name
Hospital Clinic de Barcelona
City
Barcelona
ZIP/Postal Code
08036
Country
Spain
Facility Name
Hospital Universitario Ramon y Cajal
City
Madrid
ZIP/Postal Code
28034
Country
Spain
Facility Name
Hospital Universitario Doctor Peset
City
Valencia
ZIP/Postal Code
46017
Country
Spain
Facility Name
Hospital Universitari i Politecnic La Fe de Valencia
City
Valencia
ZIP/Postal Code
46026
Country
Spain
Facility Name
Hospital Viamed Montecanal
City
Zaragoza
ZIP/Postal Code
50012
Country
Spain
Facility Name
Re: Cognition Health - Guildford
City
Guildford
State/Province
Surrey
ZIP/Postal Code
GU2 7YD
Country
United Kingdom
Facility Name
Re:Cognition Health Bristol
City
Bristol
ZIP/Postal Code
BS32 4SY
Country
United Kingdom
Facility Name
Re:Cognition Health London
City
London
ZIP/Postal Code
W1G 9JF
Country
United Kingdom
Facility Name
The National Hospital for Neurology and Neurosurgery
City
London
ZIP/Postal Code
WC1N 3BG
Country
United Kingdom
Facility Name
Greater Manchester Mental Health NHS Foundation Trust
City
Manchester
ZIP/Postal Code
M8 5RB
Country
United Kingdom
Facility Name
Glasgow Memory Clinic
City
Motherwell
ZIP/Postal Code
ML1 4UF
Country
United Kingdom
Facility Name
Re:Cognition Health Plymouth
City
Plymouth
ZIP/Postal Code
Pl6 8BT
Country
United Kingdom
12. IPD Sharing Statement
Learn more about this trial
A Phase 2 Study to Evaluate Efficacy and Safety of AL002 in Participants With Early Alzheimer's Disease
We'll reach out to this number within 24 hrs