A Pilot Study to Explore the Use of Skin Biopsy as Diagnostic Tool in Anterior Cutaneous Nerve Entrapment Syndrome (ACNES) (Biopsy-ACNES)
Anterior Cutaneous Nerve Entrapment Syndrome, Nerve Entrapment Syndrome, Chronic Pain Syndrome
About this trial
This is an interventional diagnostic trial for Anterior Cutaneous Nerve Entrapment Syndrome focused on measuring Diagnostic test for ACNES, Intraepidermal nerve fibre density (IENFD)
Eligibility Criteria
Inclusion Criteria: Duration of pain >3 months Newly diagnosed unilateral ACNES Fully completed intake questionnaire Obtained written informed consent Exclusion Criteria: Inability to understand Dutch language Bilateral ACNES Previously administered injections with corticosteroids at trigger point (injection with a local anaesthetic is allowed) Previous Pulsed Radiofrequency (PRF)-treatment at trigger point History of open abdominal surgery History of neurectomy Known neuromuscular or neurodegenerative disease Antiplatelet or anticoagulants use or known coagulation disorders Disorder known to cause a reduced IENFD; Diabetes Hypothyroidism Renal failure Vitamin B12 deficiency Monoclonal gammopathy Alcohol abuse (>5 IU a day) Malignancies Medication that cause neuropathy (for example chemotherapy)
Sites / Locations
- Maxima Medical CenterRecruiting
Arms of the Study
Arm 1
Experimental
Patients with unilateral ACNES