A Preliminary Study of Model-driven Individualized Transcranial Electrical Stimulation for Insomnia
Insomnia
About this trial
This is an interventional treatment trial for Insomnia focused on measuring Transcranial electrical stimulation
Eligibility Criteria
Inclusion Criteria:
Between 18 and 50 years old;
The patients were diagnosed as insomnia according to the diagnostic and Statistical Manual of Mental Disorders (DSM-5) and Mini-International Neuropsychiatric Interview (M.I.N.I.) .
- No psychiatric drugs were taken within 8 weeks before enrollment; ④ Junior high school education or above.
Exclusion Criteria:
Past or current DSM-5 diagnoses other than insomnia, anxiety disorder and depressive disorder
Severe anxiety or depression (HAMD-17 > 23 points or HAMA > 30 points)
Patients with obstructive sleep apnea syndrome;
Participants with claustrophobic, heart pacemaker, mechanical heart valve, mechanical implant such as an aneurysm clip, hip replacement, or any other pieces of metal that have accidentally entered their body.
- Previous history of neurological diseases (such as epilepsy, cerebrovascular accidents, etc.) or brain trauma, brain surgery; ⑥Have received ECT, rTMS, tES, or cognitive behavioral therapy for insomnia; ⑦Any current significant medical condition. ⑧Women who are pregnant or planning to become pregnant recently
Sites / Locations
- Shanghai Mental Health CenterRecruiting
Arms of the Study
Arm 1
Experimental
tES treatment
The stimulation type is cathode direct current stimulation and alternating current stimulation. The maximum stimulation current of a single channel is not more than 3mA. The frequency of electrical stimulation was 0-10Hz; DLPFC was preferentially selected for electrical stimulation, and other candidate brain regions were: orbitofrontal cortex premotor cortex, motor cortex, sensorimotor cortex, auditory cortex, posterior parietal cortex, and cerebellar cortex. The brain state changes caused by each stimulus parameter combination were compared with sleep state to determine the optimal stimulus parameters. Each cycle of stimulation was 2 weeks, once a night on weekdays, a total of 10 times