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A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension

Primary Purpose

PAH, Pulmonary Hypertension, Pulmonary Arterial Hypertension

Status
Enrolling by invitation
Phase
Phase 3
Locations
International
Study Type
Interventional
Intervention
Ralinepag
Sponsored by
United Therapeutics
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional treatment trial for PAH focused on measuring Prostacyclin, Connective Tissue Disease-Associated, 6 Minute Walk Test, 6 Minute Walk Distance, Pulmonary Vascular Resistance, Right Ventricular Function

Eligibility Criteria

18 Years - undefined (Adult, Older Adult)All SexesDoes not accept healthy volunteers

Inclusion Criteria:

  1. Evidence of a personally signed and dated informed consent form indicating that the subject has been informed of all pertinent aspects of the study prior to initiation of any study-related procedures.
  2. Subjects who are willing and able to comply with scheduled visits, treatment plan, laboratory tests, and other study procedures.
  3. Completed the protocol-defined Study Drug Termination Visit or End of Study Visit procedures in the preceding ralinepag study.
  4. Both male and female subjects agree to use a medically acceptable method of contraception throughout the entire study period from informed consent through the 30 day Follow-up Visit, if the possibility of conception exists. Eligible male and female subjects must also agree not to participate in a conception process (i.e., actively attempt to become pregnant or to impregnate, sperm donation, in vitro fertilization) during the study and for 30 days after the last dose of ralinepag.

Exclusion Criteria:

  1. Subjects who prematurely discontinued investigational medicinal product (IMP) due to a drug-related AE/SAE or tolerability issue in the preceding ralinepag study in which they were enrolled, or subjects who did not complete all protocol defined study procedures at a Study Drug Termination Visit or End of Study Visit in the preceding ralinepag study.
  2. Subjects who withdrew consent during participation in another ralinepag study.
  3. Female subjects who wish to become pregnant or who have a positive pregnancy test on Day 1 (OLE Entry Visit), or are lactating or breastfeeding.
  4. Subjects who have undergone lung or heart/lung transplant or the initiation of long-term parenteral or inhaled therapy with a prostacyclin during the time since participation in their original ralinepag study.
  5. Subjects who had an emergency unblinding procedure in a prior Phase 2 or 3 study.

Sites / Locations

  • University of Alabama at Birmingham
  • Mayo Clinic Scottsdale
  • University of Arizona
  • UCSD Health Sciences
  • Ronald Reagan UCLA Medical Center
  • Kaiser Permanente Los Angeles Medical Center
  • Keck Hospital of USC
  • VA Greater Los Angeles Healthcare System
  • University of California Davis Medical Center
  • Santa Barbara Cottage Hospital
  • Stanford University Medical Center
  • University of Colorado Hospital
  • National Jewish Health
  • University of Florida
  • University of Miami
  • Central Florida Pulmonary Group
  • Investigational Drug Services, AdventHealth Orlando (Drug Shipment Address)
  • Cleveland Clinic Florida
  • Emory University Hospital
  • Piedmont Healthcare Pulmonary and Critical Care Research
  • University of Chicago Medical Center
  • Community Heart and Vascular Hospital
  • St. Vincent Medical Group, Inc.
  • University of Iowa Hospitals and Clinics
  • Kentuckiana Pulmonary Research Center
  • University of Maryland Medical Center
  • Tufts Medical Center
  • Massachusetts General Hospital
  • Boston University Medical Center
  • Spectrum Health Medical Group
  • Mayo Clinic
  • Washington University School of Medicine
  • Nebraska Medical Center
  • University of New Mexico
  • NYU Langone Medical Center
  • Mount Sinai School of Medicine
  • University of Rochester
  • Duke University Medical Center
  • East Carolina University
  • University of Cincinnati-Medical Science Building
  • The Ohio State University Wexner Medical Center
  • Integris Baptist Medical Center
  • Oregon Clinic-Pulmonary West
  • Oregon Health & Science University
  • University of Pennsylvania
  • Thomas Jefferson University Hospital
  • Temple University
  • Allegheny General Hospital
  • NewSTAT, PLLC
  • Ascension Texas Cardiovascular
  • UT Southwestern Medical Center
  • Memorial Hermann Hospital
  • The Methodist Hospital Research Institute
  • Vermont Lung Center
  • Carilion Clinic Pulmonary and Sleep Medicine
  • Medical College of Wisconsin/Froedtert Hospital
  • Hospital Italiano
  • Hospital PROVINCIAL "Dr. Jose Maria Cullen"
  • Sanatorio Parque S.A.
  • Sanatorio de la Trinidad Mitre
  • Cardiologia Palmero
  • Hospital Britanico de Buenos Aires
  • Fundacion Favaloro
  • Hospital Privado Centro Medico de Cordoba S.A
  • Instituto de Cardiologia de Corrientes
  • Hospital Italiano de Cordoba
  • Instituto de Investigaciones Clinicas
  • St Vincent's Hospital Sydney
  • Royal Prince Alfred Hospital
  • Macquarie University
  • Westmead Hospital
  • Nepean Hospital
  • The Prince Charles Hospital
  • Princess Alexandra Hospital
  • Royal Hobart Hospital
  • St Vincent's Hospital Melbourne
  • The Alfred Hospital
  • Fiona Stanley Hospital
  • Medizinische Universität Innsbruck
  • Ordensklinikum Linz GmbH - Elisabethinen, Fadingerstrasse 1
  • AKH Wien, Innere Med. II, Kardiologie, Währingergürtel 18-20
  • Cliniques Universitaires de Bruxelles Hopital Erasme
  • UZ Leuven, UZ Leuven Campus Gasthuisberg, Herestraat 49
  • HC-UFG - Hospital das Clínicas da Universidade Federal de Goiás
  • Instituto das Pequenas Missionárias de Maria Imaculada - Hospital Madre Teresa
  • Hospital Sao Lucas da PUC-RS
  • Irmandade da Santa Casa de Misericórdia de Porto Alegre
  • UNESP-Faculdade de Medicina da Universidade Estadual Paulista Campus Botucatu
  • Hospital Sao Paulo
  • Instituto do Coracao
  • MHAT - "National Heart Hospital" EAD, 65, Konyovitza Str.
  • MHAT "Sveta Anna" Sofia AD
  • Peter Lougheed Centre
  • University of Alberta Hospital
  • LHSC - Victoria Hospital
  • University Health Network-Toronto General Hospital
  • SMBD Jewish General Hospital d/b/a Jewish General Hospital
  • Institut Universitaire de Cardiologie et de Pneumologie de Quebec
  • Instiuto Nacional del Torax
  • Beijing Shijitan Hospital, Capital Medical University
  • Guangdong Provincial People's Hospital
  • Xiangya Hospital Central South University
  • Shanghai Pulmonary Hospital
  • Fuwai Hospital, Chinese Academy of Medical Sciences
  • Fuwai Central China Cardiovascular Hospital
  • Clinical Hospital Dubrava Zagreb, Avenija G.Šuška 6
  • University Clinic for Pulmonary Diseases, Jordanovac 104
  • Vseobecna fakultni nemocnice v Praze, II. interni klinika kardiologie a angiologie VFN a 1. LF UK, U nemocnice 2
  • Copenhagen University Hospital (Rigshospitalet)
  • Århus Universitetshospital
  • CHU de Strasbourg - Nouvel Hôpital Civil, Ctre de competence Hypertension Arterielle Pulmona, 1 place de l Hopital
  • CHU de Grenoble - Hôpital Albert Michallon, Clinique de Cardiologie, Boulevrad de la Chantourne
  • CHU de Saint-Etienne - Hopital Nord, Service de Medecine vasculaire et therapeutique, 81 Avenue A. Raimond
  • CHU Nancy - Hôpital de Brabois Adultes, Pneumologie- Oncologie Médicale, Rue du Morvan
  • CHU Lyon - Hôpital Cardio-Vasculaire et Pneumologique Louis Pradel, Service de Pneumologie, 59 Boulevard Pinel
  • CHU de Rouen - Hôpital Charles Nicolle
  • Groupement Hospitalier Sud - Hôpital Bicêtre, Service de Pneumologie, 78 Avenue du General Leclerc
  • CHU Besançon - Hôpital Jean Minjoz
  • CHU de Brest - Hôpital de la Cavale Blanche
  • CHRU de Lille - Hopital Cardiologique
  • Hôpital Nord - CHU Marseille
  • Thoraxklinik-Heidelberg Zentrum für Pulmonale Hypertonie
  • Universitätsmedizin Greifswald
  • Universitaetsmedizin der Johannes-Gutenberg-Universitaet Mainz, Zentrum für Kardiologie I, Centrum für Thrombose und Hämostase (CTH), Langenbeckstrasse 1
  • Universitaetsklinikum des Saarlandes, Innere Medizin V, IMED, Kirrberger Strasse 100, Gebäude 41
  • Universitätsklinikum Leipzig, Medizinische Klinik II, Pneumologie
  • Schwarzwald-Baar Klinikum
  • Universitaetsklinikum Carl Gustav Carus TU Dresden
  • Universitaetsklinikum Hamburg-Eppendorf
  • University General Hospital of Alexandroupolis
  • "Onasseio" Cardiosurgery Hospital, Hemodynamic Research and Interventional Cardiology Dept., 356, Syggrou Avenue
  • University General Hospital Attikon
  • AHEPA General Hospital of Thessaloniki, A' Cardiology Clinic, 1 St. Kyriakidi Street
  • Pecsi Tudomanyegyetem, Szivgyogyaszati Klinika, Ifjusag u. 13.
  • The Lady Davis Carmel Medical Center, 7 Michal st.
  • Hadassah Ein Kerem Medical Center, Kiryat Hadassah
  • Meir Medical Center, 59 Tshernichovski st.
  • Rabin Medical Center-Beilinson Campus, Pulmonary Institute, 39 Jabotinsky St Ground floor
  • Tel Aviv Sourasky Medical Center, 6 Weizmann St.
  • Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione (ISMETT)
  • Azienda Ospedaliero Universitaria Ospedali Riuniti di Foggia, S.C. di Cardiologia, Viale Luigi Pinto, 1
  • IRCC Ospedale Policlinico San Martino
  • Fondazione IRCCS CA' Granda Ospedale Maggiore Policlinico, Via Francesco Sforza 35
  • Centro Cardiologico Monzino, IRCCS U.O. Scompenso
  • Azienda Socio Sanitaria Territoriale di Monza (Presidio San Gerardo)
  • Fondazione IRCCS Policlinico San Matteo
  • Azienda Ospedaliera Universitaria Policlinico Umberto I - Università di Roma La Sapienza, Viale del Policlinico, 155
  • Samsung Medical Center
  • Seoul National University Hospital
  • Gachon University Hospital Gil Medical Center
  • Instituto Nacional de Cardiologia Dr Ignacio Chavez Rivera
  • Instituto Nacional de Ciencias Médicas y Nutricion Dr. Salvador Zubiran
  • CICUM San Miguel
  • Unidad de Investigacion Clinica en Medicina, S.C.
  • VU Medisch Centrum, De Boelelaan 1117
  • Uniwersytecki Szpital Kliniczny w Bialymstoku, Klinika Kardiologii z Oddzialem Intensywnego Nazdoru Kardiologicznego, M. Sklodowskiej 24a
  • Krakowski Szpital Specjalistyczny im. Jana Pawla II, Oddział Kliniczny Chorób Serca i Naczyń z Pododdziałem Intensywnego Nadzoru Kardiologicznego, Pradnicka 80
  • NZOZ Europejskie Centrum Zdrowia, ul. Borowa 14/18
  • Szpital Kliniczny Przemienienia Panskiego Uniwersytetu Medycznego im. Karola Marcinkowskiego w Poznaniu, Oddzial Kardiologii - F, ul. Dluga 1/2
  • Premium Clinic Wrocław CM, Podwale 83/17
  • Hospital Garcia de Orta, E.P.E
  • Centro Hospitalar e Universitário de Coimbra, E.P.E.
  • Centro Hospitalar Universitário Lisboa Norte, E.P.E. Hospital Pulido Valente
  • Centro Hospitalar de Santo António, E.P.E.
  • Institutul de Urgenta pentru Boli Cardiovasculare "Prof. Dr. C.C. Iliescu", Sos. Fundeni nr. 258
  • Institutul de Pneumoftiziologie "Marius Nasta", Sos. Viilor nr. 90, Sector 5
  • Institutul Inimii "Niculae Stancioiu" Cluj-Napoca, Cardiologie, Str. Motilor nr. 19-21
  • Spitalul Clinic de Boli Infectioase si Pneumoftiziologie "Dr. Victor Babes" Timisoara, Str. Gheorghe Adam nr. 13
  • Clinical Center of Serbia, Koste Todorovica 8
  • Clinical Center Zemun. Clinic for internal medicine, Department of Cardiology
  • Institute for Pulmonary Diseases of Vojvodina, Put Dr Goldmana 4
  • National University Hospital
  • National Heart Centre
  • Hospital Universitari Vall d'Hebron, Respiratory Dept., Passeig Vall d'Hebron,119-129, Neumologia
  • Hospital Clinic de Barcelona, C/ Villarroel, 170
  • Hospital Universitario 12 de Octubre
  • Hospital Universitari i Politecnic La Fe
  • National Cheng Kung University Hospital
  • National Taiwan University Hospital
  • Osmangazi Uni Medical Faculty
  • Balcalı, Çukurova Üniversitesi Kardiyoloji ABD
  • Mersin Üniversitesi Tip Fakültesi Ciftlikköy Kampüsü
  • Gazi University Medical Faculty Hospital
  • Uludag Universitesi Tip Fakültesi, Gorukle Kampusu
  • Marmara Universitesi Istanbul Pendik Egitim ve Arastirma Hastanesi, Fevzi Cakmak Mahallesi Muhsin Yazicioglu Cad. No: 10
  • Dokuz Eylul Universitesi Tip Fakultesi, Mithatpasa caddesi Inciralti Balcova
  • CE Dniprop RCC&C Center of Dniprop RC Dept of Card SI DMA of MOHU, Chair of Internal Medicine 3, 28, Knyazya Volodymyra Velykogo St.
  • SI F.H.Yanovskyi National Institute of Phthisiology and Pulmonology of NAMSU, Clinical and Functional Dept, 10, Amosova St.
  • Communal Noncommercial Enterprise of Lviv Regional Council Lviv Clinical Hospital, Dept of Cardiology, D.Halytskyi Lviv NMU, Ch of Internal Medicine #1, 7, Chernihivska str.
  • Royal Free London NHS Foundation Trust, Pond Street
  • The Newcastle upon Tyne Hospitals NHS Foundation Trust, Sir William Leech Lung Research Centre, Freeman Hospital
  • Golden Jubilee National Hospital
  • Royal Brompton Hospital
  • Hammersmith Hospital

Arms of the Study

Arm 1

Arm Type

Experimental

Arm Label

Ralinepag

Arm Description

Ralinepag once daily extended-release tablets (oral) 50, 250, and 400 mcg titrated to the highest tolerated dose.

Outcomes

Primary Outcome Measures

Number of subjects with treatment-emergent adverse events [Safety and Tolerability]
The safety and tolerability of ralinepag will be evaluated by the Number of subjects with treatment-emergent adverse events

Secondary Outcome Measures

Full Information

First Posted
September 19, 2018
Last Updated
October 20, 2023
Sponsor
United Therapeutics
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1. Study Identification

Unique Protocol Identification Number
NCT03683186
Brief Title
A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension
Official Title
A Phase 3 Open-label Extension (OLE) Study to Evaluate the Long-term Safety and Efficacy of Ralinepag in Subjects With World Health Organization (WHO) Group 1 Pulmonary Arterial Hypertension (PAH)
Study Type
Interventional

2. Study Status

Record Verification Date
October 2023
Overall Recruitment Status
Enrolling by invitation
Study Start Date
September 23, 2019 (Actual)
Primary Completion Date
September 2024 (Anticipated)
Study Completion Date
September 2024 (Anticipated)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Sponsor
Name of the Sponsor
United Therapeutics

4. Oversight

Studies a U.S. FDA-regulated Drug Product
Yes
Studies a U.S. FDA-regulated Device Product
No
Data Monitoring Committee
Yes

5. Study Description

Brief Summary
Study ROR-PH-303, ADVANCE EXTENSION, is an open-label extension (OLE) study for participants with WHO Group 1 PAH who have participated in another Phase 2 or Phase 3 study of ralinepag.
Detailed Description
Study ROR-PH-303 is a multicenter, open-label extension (OLE) study for subjects with WHO Group 1 PAH who have participated in another Phase 2 or Phase 3 study of ralinepag and who qualify for entry based upon participation in the prior study. Subjects who discontinue participation in a prior study due to safety issues related to study medication or who fail to complete study procedures will not be eligible to enter Study ROR-PH-303. Subjects who meet all OLE entry criteria will be enrolled and will receive ralinepag in addition to their pre-existing PAH disease-specific background therapy. For subjects who are enrolled from an ongoing double-blind Phase 2 or Phase 3 ralinepag study, a 16-week blinded Dose Titration Period will be completed following enrollment into the OLE. Subjects previously on ralinepag will continue on the same dose during the Dose Titration Period as received in the original study and will also initiate placebo treatment in the OLE. Subjects who are enrolled from a non-blinded study or another OLE will not participate in the blinded Dose Titration Period in Study ROR-PH-303 but will be enrolled directly into the Treatment Period and continue on the dose of ralinepag received in the original study. All subjects will receive ralinepag in the OLE study until premature discontinuation of ralinepag due to an AE/serious adverse event (SAE) or other reason, marketing approval of ralinepag is granted in the region in which the study is conducted, or the study is discontinued by the Sponsor.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
PAH, Pulmonary Hypertension, Pulmonary Arterial Hypertension, Hypertension, Connective Tissue Diseases, Familial Primary Pulmonary Hypertension, Vascular Diseases, Cardiovascular Diseases, Hypertension, Pulmonary, Lung Diseases, Respiratory Tract Disease
Keywords
Prostacyclin, Connective Tissue Disease-Associated, 6 Minute Walk Test, 6 Minute Walk Distance, Pulmonary Vascular Resistance, Right Ventricular Function

7. Study Design

Primary Purpose
Treatment
Study Phase
Phase 3
Interventional Study Model
Single Group Assignment
Masking
None (Open Label)
Allocation
N/A
Enrollment
1000 (Anticipated)

8. Arms, Groups, and Interventions

Arm Title
Ralinepag
Arm Type
Experimental
Arm Description
Ralinepag once daily extended-release tablets (oral) 50, 250, and 400 mcg titrated to the highest tolerated dose.
Intervention Type
Drug
Intervention Name(s)
Ralinepag
Other Intervention Name(s)
APD811
Intervention Description
Active
Primary Outcome Measure Information:
Title
Number of subjects with treatment-emergent adverse events [Safety and Tolerability]
Description
The safety and tolerability of ralinepag will be evaluated by the Number of subjects with treatment-emergent adverse events
Time Frame
Up to 6 years

10. Eligibility

Sex
All
Minimum Age & Unit of Time
18 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria: Evidence of a personally signed and dated informed consent form indicating that the subject has been informed of all pertinent aspects of the study prior to initiation of any study-related procedures. Subjects who are willing and able to comply with scheduled visits, treatment plan, laboratory tests, and other study procedures. Completed the protocol-defined Study Drug Termination Visit or End of Study Visit procedures in the preceding ralinepag study. Both male and female subjects agree to use a medically acceptable method of contraception throughout the entire study period from informed consent through the 30 day Follow-up Visit, if the possibility of conception exists. Eligible male and female subjects must also agree not to participate in a conception process (i.e., actively attempt to become pregnant or to impregnate, sperm donation, in vitro fertilization) during the study and for 30 days after the last dose of ralinepag. Exclusion Criteria: Subjects who prematurely discontinued investigational medicinal product (IMP) due to a drug-related AE/SAE or tolerability issue in the preceding ralinepag study in which they were enrolled, or subjects who did not complete all protocol defined study procedures at a Study Drug Termination Visit or End of Study Visit in the preceding ralinepag study. Subjects who withdrew consent during participation in another ralinepag study. Female subjects who wish to become pregnant or who have a positive pregnancy test on Day 1 (OLE Entry Visit), or are lactating or breastfeeding. Subjects who have undergone lung or heart/lung transplant or the initiation of long-term parenteral or inhaled therapy with a prostacyclin during the time since participation in their original ralinepag study. Subjects who had an emergency unblinding procedure in a prior Phase 2 or 3 study.
Facility Information:
Facility Name
University of Alabama at Birmingham
City
Birmingham
State/Province
Alabama
ZIP/Postal Code
35294
Country
United States
Facility Name
Mayo Clinic Scottsdale
City
Scottsdale
State/Province
Arizona
ZIP/Postal Code
85259
Country
United States
Facility Name
University of Arizona
City
Tucson
State/Province
Arizona
ZIP/Postal Code
85724
Country
United States
Facility Name
UCSD Health Sciences
City
La Jolla
State/Province
California
ZIP/Postal Code
92037
Country
United States
Facility Name
Ronald Reagan UCLA Medical Center
City
Los Angeles
State/Province
California
ZIP/Postal Code
90024
Country
United States
Facility Name
Kaiser Permanente Los Angeles Medical Center
City
Los Angeles
State/Province
California
ZIP/Postal Code
90027
Country
United States
Facility Name
Keck Hospital of USC
City
Los Angeles
State/Province
California
ZIP/Postal Code
90033
Country
United States
Facility Name
VA Greater Los Angeles Healthcare System
City
Los Angeles
State/Province
California
ZIP/Postal Code
90073
Country
United States
Facility Name
University of California Davis Medical Center
City
Sacramento
State/Province
California
ZIP/Postal Code
95817
Country
United States
Facility Name
Santa Barbara Cottage Hospital
City
Santa Barbara
State/Province
California
ZIP/Postal Code
93105
Country
United States
Facility Name
Stanford University Medical Center
City
Stanford
State/Province
California
ZIP/Postal Code
94305
Country
United States
Facility Name
University of Colorado Hospital
City
Aurora
State/Province
Colorado
ZIP/Postal Code
80045
Country
United States
Facility Name
National Jewish Health
City
Denver
State/Province
Colorado
ZIP/Postal Code
80206
Country
United States
Facility Name
University of Florida
City
Gainesville
State/Province
Florida
ZIP/Postal Code
32610
Country
United States
Facility Name
University of Miami
City
Miami
State/Province
Florida
ZIP/Postal Code
33136
Country
United States
Facility Name
Central Florida Pulmonary Group
City
Orlando
State/Province
Florida
ZIP/Postal Code
32803
Country
United States
Facility Name
Investigational Drug Services, AdventHealth Orlando (Drug Shipment Address)
City
Orlando
State/Province
Florida
ZIP/Postal Code
32804
Country
United States
Facility Name
Cleveland Clinic Florida
City
Weston
State/Province
Florida
ZIP/Postal Code
33331
Country
United States
Facility Name
Emory University Hospital
City
Atlanta
State/Province
Georgia
ZIP/Postal Code
30322
Country
United States
Facility Name
Piedmont Healthcare Pulmonary and Critical Care Research
City
Austell
State/Province
Georgia
ZIP/Postal Code
30106
Country
United States
Facility Name
University of Chicago Medical Center
City
Chicago
State/Province
Illinois
ZIP/Postal Code
60637
Country
United States
Facility Name
Community Heart and Vascular Hospital
City
Indianapolis
State/Province
Indiana
ZIP/Postal Code
46256
Country
United States
Facility Name
St. Vincent Medical Group, Inc.
City
Indianapolis
State/Province
Indiana
ZIP/Postal Code
46260
Country
United States
Facility Name
University of Iowa Hospitals and Clinics
City
Iowa City
State/Province
Iowa
ZIP/Postal Code
52242
Country
United States
Facility Name
Kentuckiana Pulmonary Research Center
City
Louisville
State/Province
Kentucky
ZIP/Postal Code
40202
Country
United States
Facility Name
University of Maryland Medical Center
City
Baltimore
State/Province
Maryland
ZIP/Postal Code
21201
Country
United States
Facility Name
Tufts Medical Center
City
Boston
State/Province
Massachusetts
ZIP/Postal Code
02111
Country
United States
Facility Name
Massachusetts General Hospital
City
Boston
State/Province
Massachusetts
ZIP/Postal Code
02114
Country
United States
Facility Name
Boston University Medical Center
City
Boston
State/Province
Massachusetts
ZIP/Postal Code
02118
Country
United States
Facility Name
Spectrum Health Medical Group
City
Grand Rapids
State/Province
Michigan
ZIP/Postal Code
49546
Country
United States
Facility Name
Mayo Clinic
City
Rochester
State/Province
Minnesota
ZIP/Postal Code
55905
Country
United States
Facility Name
Washington University School of Medicine
City
Saint Louis
State/Province
Missouri
ZIP/Postal Code
63110
Country
United States
Facility Name
Nebraska Medical Center
City
Omaha
State/Province
Nebraska
ZIP/Postal Code
68198
Country
United States
Facility Name
University of New Mexico
City
Albuquerque
State/Province
New Mexico
ZIP/Postal Code
87131
Country
United States
Facility Name
NYU Langone Medical Center
City
New York
State/Province
New York
ZIP/Postal Code
10016
Country
United States
Facility Name
Mount Sinai School of Medicine
City
New York
State/Province
New York
ZIP/Postal Code
10029
Country
United States
Facility Name
University of Rochester
City
Rochester
State/Province
New York
ZIP/Postal Code
14642
Country
United States
Facility Name
Duke University Medical Center
City
Durham
State/Province
North Carolina
ZIP/Postal Code
27710
Country
United States
Facility Name
East Carolina University
City
Greenville
State/Province
North Carolina
ZIP/Postal Code
27834
Country
United States
Facility Name
University of Cincinnati-Medical Science Building
City
Cincinnati
State/Province
Ohio
ZIP/Postal Code
45267
Country
United States
Facility Name
The Ohio State University Wexner Medical Center
City
Columbus
State/Province
Ohio
ZIP/Postal Code
43210
Country
United States
Facility Name
Integris Baptist Medical Center
City
Oklahoma City
State/Province
Oklahoma
ZIP/Postal Code
73112
Country
United States
Facility Name
Oregon Clinic-Pulmonary West
City
Portland
State/Province
Oregon
ZIP/Postal Code
97225
Country
United States
Facility Name
Oregon Health & Science University
City
Portland
State/Province
Oregon
ZIP/Postal Code
97239
Country
United States
Facility Name
University of Pennsylvania
City
Philadelphia
State/Province
Pennsylvania
ZIP/Postal Code
19104
Country
United States
Facility Name
Thomas Jefferson University Hospital
City
Philadelphia
State/Province
Pennsylvania
ZIP/Postal Code
19107
Country
United States
Facility Name
Temple University
City
Philadelphia
State/Province
Pennsylvania
ZIP/Postal Code
19140
Country
United States
Facility Name
Allegheny General Hospital
City
Pittsburgh
State/Province
Pennsylvania
ZIP/Postal Code
15212
Country
United States
Facility Name
NewSTAT, PLLC
City
Knoxville
State/Province
Tennessee
ZIP/Postal Code
37919
Country
United States
Facility Name
Ascension Texas Cardiovascular
City
Austin
State/Province
Texas
ZIP/Postal Code
78705
Country
United States
Facility Name
UT Southwestern Medical Center
City
Dallas
State/Province
Texas
ZIP/Postal Code
75390
Country
United States
Facility Name
Memorial Hermann Hospital
City
Houston
State/Province
Texas
ZIP/Postal Code
77030
Country
United States
Facility Name
The Methodist Hospital Research Institute
City
Houston
State/Province
Texas
ZIP/Postal Code
77030
Country
United States
Facility Name
Vermont Lung Center
City
Burlington
State/Province
Vermont
ZIP/Postal Code
05446
Country
United States
Facility Name
Carilion Clinic Pulmonary and Sleep Medicine
City
Roanoke
State/Province
Virginia
ZIP/Postal Code
24014
Country
United States
Facility Name
Medical College of Wisconsin/Froedtert Hospital
City
Milwaukee
State/Province
Wisconsin
ZIP/Postal Code
53226
Country
United States
Facility Name
Hospital Italiano
City
Ciudad Autonoma de Buenos Aires
State/Province
Buenos Aires
ZIP/Postal Code
C1181ACH
Country
Argentina
Facility Name
Hospital PROVINCIAL "Dr. Jose Maria Cullen"
City
Santa Fe
State/Province
Santa Fe De La Vera Cruz
ZIP/Postal Code
3000
Country
Argentina
Facility Name
Sanatorio Parque S.A.
City
Rosario
State/Province
Santa Fe
ZIP/Postal Code
S2000DSV
Country
Argentina
Facility Name
Sanatorio de la Trinidad Mitre
City
Buenos Aires
Country
Argentina
Facility Name
Cardiologia Palmero
City
Caba
ZIP/Postal Code
1425
Country
Argentina
Facility Name
Hospital Britanico de Buenos Aires
City
Ciudad Autonoma Buenos Aires
ZIP/Postal Code
1280
Country
Argentina
Facility Name
Fundacion Favaloro
City
Ciudad Autonoma Buenos Aires
ZIP/Postal Code
C1093AAS
Country
Argentina
Facility Name
Hospital Privado Centro Medico de Cordoba S.A
City
Cordoba
ZIP/Postal Code
X5016KEH
Country
Argentina
Facility Name
Instituto de Cardiologia de Corrientes
City
Corrientes
Country
Argentina
Facility Name
Hospital Italiano de Cordoba
City
Córdoba
ZIP/Postal Code
X5004BAL
Country
Argentina
Facility Name
Instituto de Investigaciones Clinicas
City
Mar Del Plata
Country
Argentina
Facility Name
St Vincent's Hospital Sydney
City
Darlinghurst
State/Province
New South Wales
ZIP/Postal Code
2010
Country
Australia
Facility Name
Royal Prince Alfred Hospital
City
Sydney
State/Province
New South Wales
ZIP/Postal Code
2050
Country
Australia
Facility Name
Macquarie University
City
Sydney
State/Province
New South Wales
ZIP/Postal Code
2109
Country
Australia
Facility Name
Westmead Hospital
City
Sydney
State/Province
New South Wales
ZIP/Postal Code
2145
Country
Australia
Facility Name
Nepean Hospital
City
Sydney
State/Province
New South Wales
ZIP/Postal Code
2751
Country
Australia
Facility Name
The Prince Charles Hospital
City
Chermside
State/Province
Queensland
ZIP/Postal Code
4032
Country
Australia
Facility Name
Princess Alexandra Hospital
City
Woolloongabba
State/Province
Queensland
ZIP/Postal Code
4102
Country
Australia
Facility Name
Royal Hobart Hospital
City
Hobart
State/Province
Tasmania
ZIP/Postal Code
7000
Country
Australia
Facility Name
St Vincent's Hospital Melbourne
City
Fitzroy
State/Province
Victoria
ZIP/Postal Code
3065
Country
Australia
Facility Name
The Alfred Hospital
City
Melbourne
State/Province
Victoria
ZIP/Postal Code
3004
Country
Australia
Facility Name
Fiona Stanley Hospital
City
Perth
State/Province
Western Australia
ZIP/Postal Code
6150
Country
Australia
Facility Name
Medizinische Universität Innsbruck
City
Innsbruck
ZIP/Postal Code
6020
Country
Austria
Facility Name
Ordensklinikum Linz GmbH - Elisabethinen, Fadingerstrasse 1
City
Linz
ZIP/Postal Code
4020
Country
Austria
Facility Name
AKH Wien, Innere Med. II, Kardiologie, Währingergürtel 18-20
City
Wien
ZIP/Postal Code
1090
Country
Austria
Facility Name
Cliniques Universitaires de Bruxelles Hopital Erasme
City
Bruxelles
ZIP/Postal Code
1070
Country
Belgium
Facility Name
UZ Leuven, UZ Leuven Campus Gasthuisberg, Herestraat 49
City
Leuven
ZIP/Postal Code
3000
Country
Belgium
Facility Name
HC-UFG - Hospital das Clínicas da Universidade Federal de Goiás
City
Goiânia
State/Province
Goias
ZIP/Postal Code
74605-020
Country
Brazil
Facility Name
Instituto das Pequenas Missionárias de Maria Imaculada - Hospital Madre Teresa
City
Belo Horizonte
State/Province
MG
ZIP/Postal Code
30441-070
Country
Brazil
Facility Name
Hospital Sao Lucas da PUC-RS
City
Porto Alegre
State/Province
R.S
ZIP/Postal Code
90610-000
Country
Brazil
Facility Name
Irmandade da Santa Casa de Misericórdia de Porto Alegre
City
Porto Alegre
State/Province
RS
ZIP/Postal Code
90035-074
Country
Brazil
Facility Name
UNESP-Faculdade de Medicina da Universidade Estadual Paulista Campus Botucatu
City
Botucatu
State/Province
Sao Paulo
ZIP/Postal Code
18618-687
Country
Brazil
Facility Name
Hospital Sao Paulo
City
Sao Paulo
State/Province
SP
ZIP/Postal Code
04037-002
Country
Brazil
Facility Name
Instituto do Coracao
City
Sao Paulo
State/Province
SP
ZIP/Postal Code
05403-000
Country
Brazil
Facility Name
MHAT - "National Heart Hospital" EAD, 65, Konyovitza Str.
City
Sofia
ZIP/Postal Code
1309
Country
Bulgaria
Facility Name
MHAT "Sveta Anna" Sofia AD
City
Sofia
ZIP/Postal Code
1750
Country
Bulgaria
Facility Name
Peter Lougheed Centre
City
Calgary
State/Province
Alberta
ZIP/Postal Code
T1Y 6J4
Country
Canada
Facility Name
University of Alberta Hospital
City
Edmonton
State/Province
Alberta
ZIP/Postal Code
T6G 2B7
Country
Canada
Facility Name
LHSC - Victoria Hospital
City
London
State/Province
Ontario
ZIP/Postal Code
N6A 5W9
Country
Canada
Facility Name
University Health Network-Toronto General Hospital
City
Toronto
State/Province
Ontario
ZIP/Postal Code
M5G 2N2
Country
Canada
Facility Name
SMBD Jewish General Hospital d/b/a Jewish General Hospital
City
Montreal
State/Province
Quebec
ZIP/Postal Code
H3T1E2
Country
Canada
Facility Name
Institut Universitaire de Cardiologie et de Pneumologie de Quebec
City
Québec
State/Province
Quebec
Country
Canada
Facility Name
Instiuto Nacional del Torax
City
Providencia
State/Province
Santiago De Chile
ZIP/Postal Code
7500691
Country
Chile
Facility Name
Beijing Shijitan Hospital, Capital Medical University
City
Beijing
State/Province
Beijing
ZIP/Postal Code
100038
Country
China
Facility Name
Guangdong Provincial People's Hospital
City
Guangzhou
State/Province
Guangdong
ZIP/Postal Code
510080
Country
China
Facility Name
Xiangya Hospital Central South University
City
Changsha
State/Province
Hunan
ZIP/Postal Code
410008
Country
China
Facility Name
Shanghai Pulmonary Hospital
City
Shanghai
State/Province
Shanghai
ZIP/Postal Code
200443
Country
China
Facility Name
Fuwai Hospital, Chinese Academy of Medical Sciences
City
Beijing
ZIP/Postal Code
100037
Country
China
Facility Name
Fuwai Central China Cardiovascular Hospital
City
Zhengzhou
ZIP/Postal Code
450000
Country
China
Facility Name
Clinical Hospital Dubrava Zagreb, Avenija G.Šuška 6
City
Zagreb
ZIP/Postal Code
10000
Country
Croatia
Facility Name
University Clinic for Pulmonary Diseases, Jordanovac 104
City
Zagreb
ZIP/Postal Code
10000
Country
Croatia
Facility Name
Vseobecna fakultni nemocnice v Praze, II. interni klinika kardiologie a angiologie VFN a 1. LF UK, U nemocnice 2
City
Praha 2
ZIP/Postal Code
128 08
Country
Czechia
Facility Name
Copenhagen University Hospital (Rigshospitalet)
City
Copenhagen
ZIP/Postal Code
2100
Country
Denmark
Facility Name
Århus Universitetshospital
City
Århus
ZIP/Postal Code
8200
Country
Denmark
Facility Name
CHU de Strasbourg - Nouvel Hôpital Civil, Ctre de competence Hypertension Arterielle Pulmona, 1 place de l Hopital
City
Strasbourg
State/Province
Bas Rhin
ZIP/Postal Code
67091
Country
France
Facility Name
CHU de Grenoble - Hôpital Albert Michallon, Clinique de Cardiologie, Boulevrad de la Chantourne
City
Grenoble
State/Province
Isere
ZIP/Postal Code
38048
Country
France
Facility Name
CHU de Saint-Etienne - Hopital Nord, Service de Medecine vasculaire et therapeutique, 81 Avenue A. Raimond
City
Saint-Étienne
State/Province
Loire
ZIP/Postal Code
42005
Country
France
Facility Name
CHU Nancy - Hôpital de Brabois Adultes, Pneumologie- Oncologie Médicale, Rue du Morvan
City
Vandoeuvre les Nancy
State/Province
Meurthe Et Moselle
ZIP/Postal Code
54511
Country
France
Facility Name
CHU Lyon - Hôpital Cardio-Vasculaire et Pneumologique Louis Pradel, Service de Pneumologie, 59 Boulevard Pinel
City
Bron cedex
State/Province
Rhone
ZIP/Postal Code
69677
Country
France
Facility Name
CHU de Rouen - Hôpital Charles Nicolle
City
Rouen cedex
State/Province
Seine Maritime
ZIP/Postal Code
76031
Country
France
Facility Name
Groupement Hospitalier Sud - Hôpital Bicêtre, Service de Pneumologie, 78 Avenue du General Leclerc
City
Le Kremlin-Bicêtre
State/Province
Val De Marne
ZIP/Postal Code
94275
Country
France
Facility Name
CHU Besançon - Hôpital Jean Minjoz
City
Besançon Cedex
ZIP/Postal Code
25030
Country
France
Facility Name
CHU de Brest - Hôpital de la Cavale Blanche
City
Brest cedex 2
ZIP/Postal Code
29609
Country
France
Facility Name
CHRU de Lille - Hopital Cardiologique
City
Lille Cedex
ZIP/Postal Code
59037
Country
France
Facility Name
Hôpital Nord - CHU Marseille
City
Marseille
ZIP/Postal Code
13015
Country
France
Facility Name
Thoraxklinik-Heidelberg Zentrum für Pulmonale Hypertonie
City
Heidelberg
State/Province
Baden-Württemberg
ZIP/Postal Code
69126
Country
Germany
Facility Name
Universitätsmedizin Greifswald
City
Greifswald
State/Province
Mecklenburg-Vorpommern
ZIP/Postal Code
17475
Country
Germany
Facility Name
Universitaetsmedizin der Johannes-Gutenberg-Universitaet Mainz, Zentrum für Kardiologie I, Centrum für Thrombose und Hämostase (CTH), Langenbeckstrasse 1
City
Mainz
State/Province
Rheinland Pfalz
ZIP/Postal Code
55131
Country
Germany
Facility Name
Universitaetsklinikum des Saarlandes, Innere Medizin V, IMED, Kirrberger Strasse 100, Gebäude 41
City
Homburg
State/Province
Saarland
ZIP/Postal Code
66424
Country
Germany
Facility Name
Universitätsklinikum Leipzig, Medizinische Klinik II, Pneumologie
City
Leipzig
State/Province
Sachsen
ZIP/Postal Code
04103
Country
Germany
Facility Name
Schwarzwald-Baar Klinikum
City
Donaueschingen
ZIP/Postal Code
78166
Country
Germany
Facility Name
Universitaetsklinikum Carl Gustav Carus TU Dresden
City
Dresden
ZIP/Postal Code
01307
Country
Germany
Facility Name
Universitaetsklinikum Hamburg-Eppendorf
City
Hamburg
ZIP/Postal Code
20246
Country
Germany
Facility Name
University General Hospital of Alexandroupolis
City
Alexandroupolis
ZIP/Postal Code
68100
Country
Greece
Facility Name
"Onasseio" Cardiosurgery Hospital, Hemodynamic Research and Interventional Cardiology Dept., 356, Syggrou Avenue
City
Athens
ZIP/Postal Code
17674
Country
Greece
Facility Name
University General Hospital Attikon
City
Chaidari
ZIP/Postal Code
12462
Country
Greece
Facility Name
AHEPA General Hospital of Thessaloniki, A' Cardiology Clinic, 1 St. Kyriakidi Street
City
Thessaloniki
ZIP/Postal Code
54636
Country
Greece
Facility Name
Pecsi Tudomanyegyetem, Szivgyogyaszati Klinika, Ifjusag u. 13.
City
Pecs
ZIP/Postal Code
7624
Country
Hungary
Facility Name
The Lady Davis Carmel Medical Center, 7 Michal st.
City
Haifa
ZIP/Postal Code
3436212
Country
Israel
Facility Name
Hadassah Ein Kerem Medical Center, Kiryat Hadassah
City
Jerusalem
ZIP/Postal Code
9112001
Country
Israel
Facility Name
Meir Medical Center, 59 Tshernichovski st.
City
Kfar- Sava
ZIP/Postal Code
4428164
Country
Israel
Facility Name
Rabin Medical Center-Beilinson Campus, Pulmonary Institute, 39 Jabotinsky St Ground floor
City
Petach Tikva
ZIP/Postal Code
4941492
Country
Israel
Facility Name
Tel Aviv Sourasky Medical Center, 6 Weizmann St.
City
Tel Aviv
ZIP/Postal Code
6423906
Country
Israel
Facility Name
Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione (ISMETT)
City
Palermo
State/Province
PA
ZIP/Postal Code
90127
Country
Italy
Facility Name
Azienda Ospedaliero Universitaria Ospedali Riuniti di Foggia, S.C. di Cardiologia, Viale Luigi Pinto, 1
City
Foggia
ZIP/Postal Code
71100
Country
Italy
Facility Name
IRCC Ospedale Policlinico San Martino
City
Genova
ZIP/Postal Code
16132
Country
Italy
Facility Name
Fondazione IRCCS CA' Granda Ospedale Maggiore Policlinico, Via Francesco Sforza 35
City
Milano
ZIP/Postal Code
20122
Country
Italy
Facility Name
Centro Cardiologico Monzino, IRCCS U.O. Scompenso
City
Milan
ZIP/Postal Code
20138
Country
Italy
Facility Name
Azienda Socio Sanitaria Territoriale di Monza (Presidio San Gerardo)
City
Monza
ZIP/Postal Code
20900
Country
Italy
Facility Name
Fondazione IRCCS Policlinico San Matteo
City
Pavia
ZIP/Postal Code
27100
Country
Italy
Facility Name
Azienda Ospedaliera Universitaria Policlinico Umberto I - Università di Roma La Sapienza, Viale del Policlinico, 155
City
Roma
ZIP/Postal Code
00161
Country
Italy
Facility Name
Samsung Medical Center
City
Seoul
State/Province
Gangnam-gu
ZIP/Postal Code
06351
Country
Korea, Republic of
Facility Name
Seoul National University Hospital
City
Seoul
State/Province
Jongno-gu
ZIP/Postal Code
03080
Country
Korea, Republic of
Facility Name
Gachon University Hospital Gil Medical Center
City
Incheon
State/Province
Namdong-gu
ZIP/Postal Code
21565
Country
Korea, Republic of
Facility Name
Instituto Nacional de Cardiologia Dr Ignacio Chavez Rivera
City
Mexico
State/Province
Distrito Federal
ZIP/Postal Code
14080
Country
Mexico
Facility Name
Instituto Nacional de Ciencias Médicas y Nutricion Dr. Salvador Zubiran
City
Mexico
State/Province
Distrito Federal
ZIP/Postal Code
14080
Country
Mexico
Facility Name
CICUM San Miguel
City
Guadalajara
State/Province
Jalisco
ZIP/Postal Code
44160
Country
Mexico
Facility Name
Unidad de Investigacion Clinica en Medicina, S.C.
City
Monterrey
State/Province
N.l.
ZIP/Postal Code
64718
Country
Mexico
Facility Name
VU Medisch Centrum, De Boelelaan 1117
City
Amsterdam
ZIP/Postal Code
1081 HV
Country
Netherlands
Facility Name
Uniwersytecki Szpital Kliniczny w Bialymstoku, Klinika Kardiologii z Oddzialem Intensywnego Nazdoru Kardiologicznego, M. Sklodowskiej 24a
City
Bialystok
ZIP/Postal Code
15-276
Country
Poland
Facility Name
Krakowski Szpital Specjalistyczny im. Jana Pawla II, Oddział Kliniczny Chorób Serca i Naczyń z Pododdziałem Intensywnego Nadzoru Kardiologicznego, Pradnicka 80
City
Krakow
ZIP/Postal Code
31-202
Country
Poland
Facility Name
NZOZ Europejskie Centrum Zdrowia, ul. Borowa 14/18
City
Otwock
ZIP/Postal Code
05-400
Country
Poland
Facility Name
Szpital Kliniczny Przemienienia Panskiego Uniwersytetu Medycznego im. Karola Marcinkowskiego w Poznaniu, Oddzial Kardiologii - F, ul. Dluga 1/2
City
Poznan
ZIP/Postal Code
61-848
Country
Poland
Facility Name
Premium Clinic Wrocław CM, Podwale 83/17
City
Wroclaw
ZIP/Postal Code
50-414
Country
Poland
Facility Name
Hospital Garcia de Orta, E.P.E
City
Almada
ZIP/Postal Code
2805-267
Country
Portugal
Facility Name
Centro Hospitalar e Universitário de Coimbra, E.P.E.
City
Coimbra
ZIP/Postal Code
3000-075
Country
Portugal
Facility Name
Centro Hospitalar Universitário Lisboa Norte, E.P.E. Hospital Pulido Valente
City
Lisboa
ZIP/Postal Code
1769-001
Country
Portugal
Facility Name
Centro Hospitalar de Santo António, E.P.E.
City
Porto
ZIP/Postal Code
4099-001
Country
Portugal
Facility Name
Institutul de Urgenta pentru Boli Cardiovasculare "Prof. Dr. C.C. Iliescu", Sos. Fundeni nr. 258
City
Bucharest
ZIP/Postal Code
022328
Country
Romania
Facility Name
Institutul de Pneumoftiziologie "Marius Nasta", Sos. Viilor nr. 90, Sector 5
City
Bucuresti
ZIP/Postal Code
050159
Country
Romania
Facility Name
Institutul Inimii "Niculae Stancioiu" Cluj-Napoca, Cardiologie, Str. Motilor nr. 19-21
City
Cluj-Napoca
ZIP/Postal Code
400001
Country
Romania
Facility Name
Spitalul Clinic de Boli Infectioase si Pneumoftiziologie "Dr. Victor Babes" Timisoara, Str. Gheorghe Adam nr. 13
City
Timisoara
ZIP/Postal Code
300310
Country
Romania
Facility Name
Clinical Center of Serbia, Koste Todorovica 8
City
Belgrade
ZIP/Postal Code
11000
Country
Serbia
Facility Name
Clinical Center Zemun. Clinic for internal medicine, Department of Cardiology
City
Belgrade
ZIP/Postal Code
11080
Country
Serbia
Facility Name
Institute for Pulmonary Diseases of Vojvodina, Put Dr Goldmana 4
City
Sremska Kamenica
ZIP/Postal Code
21204
Country
Serbia
Facility Name
National University Hospital
City
Singapore
ZIP/Postal Code
119074
Country
Singapore
Facility Name
National Heart Centre
City
Singapore
ZIP/Postal Code
169609
Country
Singapore
Facility Name
Hospital Universitari Vall d'Hebron, Respiratory Dept., Passeig Vall d'Hebron,119-129, Neumologia
City
Barcelona
ZIP/Postal Code
08035
Country
Spain
Facility Name
Hospital Clinic de Barcelona, C/ Villarroel, 170
City
Barcelona
ZIP/Postal Code
08036
Country
Spain
Facility Name
Hospital Universitario 12 de Octubre
City
Madrid
ZIP/Postal Code
28041
Country
Spain
Facility Name
Hospital Universitari i Politecnic La Fe
City
Valencia
ZIP/Postal Code
46026
Country
Spain
Facility Name
National Cheng Kung University Hospital
City
Tainan
ZIP/Postal Code
704
Country
Taiwan
Facility Name
National Taiwan University Hospital
City
Taipei
ZIP/Postal Code
10002
Country
Taiwan
Facility Name
Osmangazi Uni Medical Faculty
City
Eskişehir
State/Province
Odumpazari
ZIP/Postal Code
26480
Country
Turkey
Facility Name
Balcalı, Çukurova Üniversitesi Kardiyoloji ABD
City
Adana
State/Province
Saricam
ZIP/Postal Code
01330
Country
Turkey
Facility Name
Mersin Üniversitesi Tip Fakültesi Ciftlikköy Kampüsü
City
Mersin
State/Province
Yenisehir
ZIP/Postal Code
33343
Country
Turkey
Facility Name
Gazi University Medical Faculty Hospital
City
Ankara
ZIP/Postal Code
06560
Country
Turkey
Facility Name
Uludag Universitesi Tip Fakültesi, Gorukle Kampusu
City
Bursa
ZIP/Postal Code
16059
Country
Turkey
Facility Name
Marmara Universitesi Istanbul Pendik Egitim ve Arastirma Hastanesi, Fevzi Cakmak Mahallesi Muhsin Yazicioglu Cad. No: 10
City
Istanbul
ZIP/Postal Code
34899
Country
Turkey
Facility Name
Dokuz Eylul Universitesi Tip Fakultesi, Mithatpasa caddesi Inciralti Balcova
City
Izmir
ZIP/Postal Code
35340
Country
Turkey
Facility Name
CE Dniprop RCC&C Center of Dniprop RC Dept of Card SI DMA of MOHU, Chair of Internal Medicine 3, 28, Knyazya Volodymyra Velykogo St.
City
Dnipro
ZIP/Postal Code
49070
Country
Ukraine
Facility Name
SI F.H.Yanovskyi National Institute of Phthisiology and Pulmonology of NAMSU, Clinical and Functional Dept, 10, Amosova St.
City
Kyiv
ZIP/Postal Code
03680
Country
Ukraine
Facility Name
Communal Noncommercial Enterprise of Lviv Regional Council Lviv Clinical Hospital, Dept of Cardiology, D.Halytskyi Lviv NMU, Ch of Internal Medicine #1, 7, Chernihivska str.
City
Lviv
ZIP/Postal Code
79010
Country
Ukraine
Facility Name
Royal Free London NHS Foundation Trust, Pond Street
City
London
State/Province
Greater London
ZIP/Postal Code
NW3 2QG
Country
United Kingdom
Facility Name
The Newcastle upon Tyne Hospitals NHS Foundation Trust, Sir William Leech Lung Research Centre, Freeman Hospital
City
Newcastle upon Tyne
State/Province
Tyne & Wear
ZIP/Postal Code
NE7 7DN
Country
United Kingdom
Facility Name
Golden Jubilee National Hospital
City
Glasgow
State/Province
West Dunbartonshire
ZIP/Postal Code
G81 4DY
Country
United Kingdom
Facility Name
Royal Brompton Hospital
City
London
ZIP/Postal Code
SW3 6NP
Country
United Kingdom
Facility Name
Hammersmith Hospital
City
London
ZIP/Postal Code
W12 0HS
Country
United Kingdom

12. IPD Sharing Statement

Learn more about this trial

A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension

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