A Study Evaluating the Safety and Efficacy of Treating Sinus Infection With Levofloxacin 750 mg for 5 Days.
Maxillary Sinusitis
About this trial
This is an interventional treatment trial for Maxillary Sinusitis focused on measuring Maxillary Sinusitis, Infection
Eligibility Criteria
Inclusion Criteria: Clinical signs and symptoms of acute maxillary sinusitis for 5 to 28 days Visible nasal purulence evident on physical examination CT scan or standard sinus x-ray (Waters' projections) performed within 5 days prior to the first dose of study drug, showing total sinus opacification or an air-fluid level Agree to a maxillary sinus puncture and catheter placement If female, using birth control Exclusion Criteria: Chronic sinusitis Need for hospitalization or intravenous antibiotics History of head, neck, or nasal cancer or surgery Previous allergy, serious adverse reaction to, or failed therapy with, levofloxacin or any other member of the quinolone class Presence or history of serious complications of sinusitis Previous antimicrobial therapy within 7 days of Study Entry