A Study of Combivir Plus Abacavir Plus 141W94 in Patients Who Previously Have Used Anti-HIV Drugs

Inclusion Criteria Patients must have: CD4 count greater than 50 cells/mm3. HIV RNA less than 50,000 copies/ml. No active AIDS (excluding CD4 count less than 200 cells/mm3). Ability to comply with dosing schedule and protocol evaluations. Prior Medication: Allowed: AZT or non-nucleoside reverse transcriptase inhibitors (NNRTIs). Exclusion Criteria Co-existing Condition: Patients with any of the following symptoms or conditions are excluded: Active AIDS (not excluding CD4 count less than 200). Malabsorption syndrome affecting drug absorption. Serious medical condition that would compromise safety of the patient. Concurrent Medication: Excluded: AZT or NNRTIs. More than 1 week treatment with any protease inhibitor. Enrollment in any other investigational drug protocol. Patients with the following prior conditions are excluded: History of clinically relevant pancreatitis or hepatitis within the past 6 months. Required: Antiretroviral therapy with either single or double reverse transcriptase inhibitors.