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A Study of Olezarsen (ISIS 678354) in Participants With Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease, or With Severe Hypertriglyceridemia

Primary Purpose

Hypertriglyceridemia, Cardiovascular Diseases, Atherosclerosis

Status
Recruiting
Phase
Phase 3
Locations
International
Study Type
Interventional
Intervention
Olezarsen
Placebo
Sponsored by
Ionis Pharmaceuticals, Inc.
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional treatment trial for Hypertriglyceridemia focused on measuring ISIS 678354, Olezarsen

Eligibility Criteria

18 Years - undefined (Adult, Older Adult)All SexesDoes not accept healthy volunteers

Inclusion Criteria: Participants must fall into 1 of the following groups (a or b): a. Hypertriglyceridemia with fasting TG ≥200 mg/dL (2.26 millimoles per liter [mmol/L]) and <500 mg/dL (5.65 mmol/L) with either Clinical diagnosis of atherosclerotic cardiovascular disease (ASCVD) or At increased risk for ASCVD b. Severe hypertriglyceridemia with fasting TG ≥500 mg/dL (5.65 mmol/L) Participants should be on standard of care (SOC) lipid-lowering medications per local guidelines. Lipid-lowering medications should be optimized and stabilized for at least 4 weeks prior to Screening to minimize changes in these medications during the study. Exclusion Criteria: Hemoglobin A1c (HbA1c) ≥ 9.5% at Screening Alanine aminotransferase or aspartate aminotransferase > 3.0 × upper limit of normal Total bilirubin > 1.5 upper limit of normal unless due to Gilbert's syndrome Estimated GFR < 30 mL/min/1.73 m^2 NOTE: Other Inclusion/Exclusion criteria may apply.

Sites / Locations

  • Alabama Clinical Therapeutics, LLC AlabasterRecruiting
  • Heart Center Research PCRecruiting
  • Cardiovascular Research Foundation of Southern CaliforniaRecruiting
  • Westside Medical Associates of Los AngelesRecruiting
  • Diabetes/Lipid Management & Research CenterRecruiting
  • University of California, San Diego (UCSD)Recruiting
  • Clinical Trials ResearchRecruiting
  • Amicis ResearchRecruiting
  • Valley Clinical Trials, Inc.Recruiting
  • Northern California ResearchRecruiting
  • Amicis Research CenterRecruiting
  • Metabolic Institute of AmericaRecruiting
  • Lundquist Institute for Biomedical Innovation at Harbor UCLA Medical CenterRecruiting
  • Amicis Research CenterRecruiting
  • Excel Clinical Medical TrialsRecruiting
  • Finlay Medical Research - West PalmRecruiting
  • Global Research AssociatesRecruiting
  • 3Sync ResearchRecruiting
  • Finlay Medical ResearchRecruiting
  • Advanced Medical Research Institute (AMRI)Recruiting
  • De La Cruz Research Center, LLRecruiting
  • Suncoast Clinical Research, Inc. - New Port RicheyRecruiting
  • Suncoast Clinical Research, Inc. - Palm HarborRecruiting
  • Proactive Clinical ResearchRecruiting
  • Ocala Cardiovascular ResearchRecruiting
  • Comprehensive Medical & Research CenterRecruiting
  • Progressive Medical ResearchRecruiting
  • St. Johns Center for Clinical ResearchRecruiting
  • JSV Clinical Research Study, IncRecruiting
  • Centricity ResearchRecruiting
  • Atlanta Heart SpecialistsRecruiting
  • Evanston Premier Healthcare Research LLCRecruiting
  • Clinical Investigation Specialists, IncRecruiting
  • Affinity HealthRecruiting
  • Cardiovascular Research of Northwest Indiana, LLCRecruiting
  • Reid Hospital and Health Care ServicesRecruiting
  • West Broadway ClinicRecruiting
  • Mercy One Iowa Heart CenterRecruiting
  • University of Kansas Medical Center (KUMC)Recruiting
  • Norton Cardiovascular AssociatesRecruiting
  • Louisville Metabolic and Atherosclerosis Research CenterRecruiting
  • Maryland Cardiovascular SpecialistsRecruiting
  • Aa Mrc, LlcRecruiting
  • Palm Research Center, Inc.Recruiting
  • Clinical Research of South NevadaRecruiting
  • Palm Research Center, Inc.Recruiting
  • Medical University of South Carolina (MUSC)Recruiting
  • Moses H. Cone Memorial HospitalRecruiting
  • Aultman Hospital Cardiology Clinical TrialsRecruiting
  • McConnell Heart Health CenterRecruiting
  • Summit Research Group, LLCRecruiting
  • Central Oklahoma Early Detection CenterRecruiting
  • Green and Seidner Family Practice AssociatesRecruiting
  • Main Street Physicians Care WaterwayRecruiting
  • OnSite Clinical Solutions, LLCRecruiting
  • Monument Health Clinical ResearchRecruiting
  • Health ConceptsRecruiting
  • The Jackson ClinicRecruiting
  • Affinity Health Corp.Recruiting
  • Tennessee Center for Clinical TrialsRecruiting
  • Baylor College of MedicineRecruiting
  • Juno Research, LLCRecruiting
  • Texas Institute of CardiologyRecruiting
  • Southern Endocrinology AssociatesRecruiting
  • FMC ScienceRecruiting
  • Carient Heart & VascularRecruiting
  • Manassas Clinical Research CenterRecruiting
  • Charleston Area Medical Center (CAMC) Clinical Trials CenterRecruiting
  • University Multiprofile Hospital for Active Treatment Pulmed OODRecruiting
  • SHATC Medica Cor EADRecruiting
  • Medical Center for Specialized Medical Help in Cardiovascular Diseases OODRecruiting
  • MBAL National Cardiology HospitalRecruiting
  • University Multiprofile Hospital for Active TreatmentRecruiting
  • Medico Dental Center ISUL Tsaritsa Yoanna EOODRecruiting
  • UMHAT Prof. Dr. Stoyan KirkovichRecruiting
  • Diagnostic Consultative Center Equita (DCC Equita)Recruiting
  • Specialized Hospital for Active Treatment of CardiologyRecruiting
  • ARC BiosystemsRecruiting
  • Centricity Research - Vaughan EndocrinologyRecruiting
  • Centricity Research - Etobicoke EndocrinologyRecruiting
  • Centricity Research - Oshawa MultispecialtyRecruiting
  • Bluewater Clinical Research Group IncRecruiting
  • Centricity Research - Toronto LMC MultispecialtyRecruiting
  • Ecogene-21Recruiting
  • Institute de Recherches Cliniques de MontrealRecruiting
  • Clinique des Maladies Lipidiques de Quebec Inc.Recruiting
  • Centricity Research - Barrie EndocrinologyRecruiting
  • Centricity Research - Brampton EndocrinologyRecruiting
  • Centre de Recherche Saint-LouisRecruiting
  • UNIVMED s.r.o. - Kardiologicka AmbulanceRecruiting
  • Edumed s.r.o., Kardiologicka, endokrinologicka, diabetologicka a interni ambulance NachodRecruiting
  • Endokrinologie Cerny Most s.r.o.Recruiting
  • Affidea Praha s.r.o.Recruiting
  • Diabetologicka a endokrinologicka ambulance Milan Kvapil s.r.oRecruiting
  • AeskuLab k.sRecruiting
  • MUDr. Nina Zemkova s.r.o. Interni AmbulanceRecruiting
  • Aarhus University HospitalRecruiting
  • Sydvestjysk HospitalRecruiting
  • Gentofte HospitalRecruiting
  • Godstrup Regional Hospital (Gødstrup)Recruiting
  • OUH Svendborg HospitalRecruiting
  • Viborg Regional HospitalRecruiting
  • HCL Hopital Louis PradelRecruiting
  • CHU Dijon Bourgogne - Hopital Francois MitterrandRecruiting
  • AP-HP Hopital Pitie-SalpetriereRecruiting
  • Groupement de Cooperation Sanitaire (GCS) ELSAN - Polyclinique VaubanRecruiting
  • GHM les Portes du SudRecruiting
  • Clinexpert Kft.Recruiting
  • Obudai Egeszsegugyi CentrumRecruiting
  • CRU Hungary Kft.Recruiting
  • ASST NORD MILANO-Ospedale Edoardo BassiniRecruiting
  • Azienda Ospedaliero-Universitaria di Ferrara-Arcispedale Sant'AnnaRecruiting
  • Centro Cardiologico MonzinoRecruiting
  • ASST Grande Ospedale Metropolitano NiguardaRecruiting
  • Azienda Ospedaliera Universitaria Policlinico Paolo GiacconeRecruiting
  • Fondazione Policlinico Universitario A. Gemelli IRCCS - Universita Cattolica del Sacro CuoreRecruiting
  • Academic Medical Center - Department of Vascular MedicineRecruiting
  • Ziekenhuis RijnstateRecruiting
  • Reinier de Graaf GasthuisRecruiting
  • Deventer ZiekenhuisRecruiting
  • Het Van Weel-Bethesda ZiekenhuisRecruiting
  • Groene Hart ZiekenhuisRecruiting
  • Spaarne GasthuisRecruiting
  • Zuyderland Medisch CentrumRecruiting
  • Bethesda Diabetes Research CenterRecruiting
  • Canisius-Wilhelmina Ziekenhuis (CWZ)Recruiting
  • D&A ResearchRecruiting
  • Universitair Medisch Centrum UtrechtRecruiting
  • Maxima Medisch CentrumRecruiting
  • Albert Schweitzer Ziekenhuis - Location DordrechtRecruiting
  • The Lipid Clinic (Oslo University Hospital)Recruiting
  • SALVIA Lekston i Madej s.j.Recruiting
  • Krakowskie Centrum Medyczne Sp. z o.o.Recruiting
  • Jagiellonskie Centrum Innowacji Sp. z o.o.Recruiting
  • Praktyka Lekarska Ewa KrzyzagorskaRecruiting
  • Clinical Best Solutions Sp. z.o.o Spolka KomandytowaRecruiting
  • Narodowy Instytut Kardiologii Stefana kardynala Wyszynskiego - Panstwowy Instytut Badawczy, Klinika Kardiologii i Angiologii InterwencyjnejRecruiting
  • FutureMeds Warszawa CentrumRecruiting
  • FutureMeds - Centrum Medyczne AMED Warszawa TargowekRecruiting
  • FutureMeds Sp. z o.oRecruiting
  • Slaski Park Technologii Medycznych Kardio-Med Silesia Sp. z o. oRecruiting
  • FutureMedsRecruiting
  • INSTYTUT CENTRUM ZDROWIA MATKI POLKI - Klinika Kardiologii i Wad Wrodzonych DoroslychRecruiting
  • Centro Hospitalar de Lisboa Ocidental. E.P.E, - Hospital Santa CruzRecruiting
  • Centro Hospitalar de Lisboa Ocidental, EPE - Hospital Egas MonizRecruiting
  • Centro Hospitalar Universitario de Lisboa Norte - Hospital de Santa MariaRecruiting
  • Centro Hospitalar de Vila Nova de Gaia/Espinho EPERecruiting
  • Alian, s.r.o., Kardiologicka ambulanciaRecruiting
  • Cardio D&R, S.R.O. KosiceRecruiting
  • Diab sroRecruiting
  • Interna SK, s.r.o., Kardiologicka a interna ambulanciaRecruiting
  • Hospital de la Santa Creu i Sant PauRecruiting
  • Calle Villarroel 170Recruiting
  • Hospital Universitario Reina SofiaRecruiting
  • Hospital Clinico Universitario Virgen de la ArrixacaRecruiting
  • Hospital Abente y LagoRecruiting
  • Hospital Clinico San CarlosRecruiting
  • Hospital Universitario Virgen de la VictoriaRecruiting
  • Hospital Universitario Virgen MacarenaRecruiting

Arms of the Study

Arm 1

Arm 2

Arm Type

Experimental

Placebo Comparator

Arm Label

Olezarsen

Placebo

Arm Description

Participants will be randomized to receive multiple doses of olezarsen, once every 4 weeks by subcutaneous (SC) injection for up to Week 49.

Participants will be randomized to receive olezarsen-matching placebo, once every 4 weeks by SC injection for up to Week 49.

Outcomes

Primary Outcome Measures

Percent Change From Baseline to Week 25 in Fasting Triglycerides (TG) Compared to Placebo

Secondary Outcome Measures

Percent Change From Baseline to Week 53 in Fasting TG Compared to Placebo
Proportion of Participants who Achieve Fasting TG <150 Milligrams per Deciliter (mg/dL) at Weeks 25 and 53 Compared to Placebo
Percent Change From Baseline to Weeks 25 and 53 in Fasting Apolipoprotein C-III (apoC-III) Compared to Placebo
Percent Change From Baseline to Weeks 25 and 53 in Fasting Very Low-Density Lipoprotein-Cholesterol (VLDL)-C Compared to Placebo
Percent Change From Baseline to Weeks 25 and 53 in Fasting Remnant Cholesterol Compared to Placebo
Percent Change From Baseline to Weeks 25 and 53 in Fasting non-High Density Lipoprotein-Cholesterol (HDL)-C Compared to Placebo
Percent Change From Baseline to Weeks 25 and 53 in Fasting High-Density Lipoprotein-Cholesterol (HDL)-C Compared to Placebo
Percent Change From Baseline to Weeks 25 and 53 in Fasting Total Cholesterol (TC) Compared to Placebo
Percent Change From Baseline to Weeks 25 and 53 in Fasting Apolipoprotein B (apoB) Compared to Placebo
Percent Change From Baseline to Weeks 25 and 53 in Fasting Apolipoprotein B-48 (apoB-48) Compared to Placebo
Percent Change From Baseline to Weeks 25 and 53 in Fasting Low-Density Lipoprotein-Cholesterol (LDL)-C Compared to Placebo
Percent Change From Baseline to Weeks 25 and 53 in Fasting Apolipoprotein A-1 (apoA-1) Compared to Placebo
Adjudicated Acute Pancreatitis Event Rate During the Treatment Period Compared to Placebo in Participants With ≥ 2 Events of Adjudicated Acute Pancreatitis in 5 Years Prior to Enrollment
Adjudicated Acute Pancreatitis Event Rate from Week 13 to Week 53 Compared to Placebo in Participants With ≥ 2 Events of Adjudicated Acute Pancreatitis in 5 Years Prior to Enrollment
Adjudicated Acute Pancreatitis Event Rate During the Treatment Period Compared to Placebo
Adjudicated Acute Pancreatitis Event Rate from Week 13 to Week 53 Compared to Placebo

Full Information

First Posted
November 2, 2022
Last Updated
October 4, 2023
Sponsor
Ionis Pharmaceuticals, Inc.
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1. Study Identification

Unique Protocol Identification Number
NCT05610280
Brief Title
A Study of Olezarsen (ISIS 678354) in Participants With Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease, or With Severe Hypertriglyceridemia
Official Title
A Randomized, Double-blind, Placebo-Controlled, Phase 3 Study of Olezarsen (ISIS 678354) in Patients With Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease (Established or at Increased Risk for), or With Severe Hypertriglyceridemia
Study Type
Interventional

2. Study Status

Record Verification Date
October 2023
Overall Recruitment Status
Recruiting
Study Start Date
November 21, 2022 (Actual)
Primary Completion Date
March 2025 (Anticipated)
Study Completion Date
June 2025 (Anticipated)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Sponsor
Name of the Sponsor
Ionis Pharmaceuticals, Inc.

4. Oversight

Studies a U.S. FDA-regulated Drug Product
Yes
Studies a U.S. FDA-regulated Device Product
No
Product Manufactured in and Exported from the U.S.
No
Data Monitoring Committee
Yes

5. Study Description

Brief Summary
The purpose of the study is to evaluate the effect of olezarsen on percent change in fasting triglyceride (TG) levels compared to placebo in participants with hypertriglyceridemia and atherosclerotic cardiovascular disease, or with severe hypertriglyceridemia.
Detailed Description
This is a Phase 3, multi-center, placebo-controlled study of up to 1312 participants with hypertriglyceridemia and atherosclerotic cardiovascular disease. The study consists of 3 periods: 1) Screening Period: Week -12 to Week -1 (up to 12 weeks); 2) Treatment Period up to Week 53; and 3) Post-Treatment Follow-up Period: Week 54 to Week 66 (13 weeks). Participants enrolled will receive olezarsen or placebo once every 4 weeks during the 53-week Treatment Period. The Screening Period was extended with no impact to overall study timelines. Endpoints added to provide assessment on the pancreatitis rate after olezarsen reaches steady state levels. A coronary computed tomographic angiography (CTA) sub study will be performed to assess whether triglyceride lowering through inhibition of apoC-III protein synthesis may reduce coronary plaque progression.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Hypertriglyceridemia, Cardiovascular Diseases, Atherosclerosis
Keywords
ISIS 678354, Olezarsen

7. Study Design

Primary Purpose
Treatment
Study Phase
Phase 3
Interventional Study Model
Parallel Assignment
Masking
ParticipantCare ProviderInvestigatorOutcomes Assessor
Allocation
Randomized
Enrollment
1312 (Anticipated)

8. Arms, Groups, and Interventions

Arm Title
Olezarsen
Arm Type
Experimental
Arm Description
Participants will be randomized to receive multiple doses of olezarsen, once every 4 weeks by subcutaneous (SC) injection for up to Week 49.
Arm Title
Placebo
Arm Type
Placebo Comparator
Arm Description
Participants will be randomized to receive olezarsen-matching placebo, once every 4 weeks by SC injection for up to Week 49.
Intervention Type
Drug
Intervention Name(s)
Olezarsen
Other Intervention Name(s)
ISIS 678354, AKCEA-APOCIII-LRx
Intervention Description
Olezarsen will be administered by SC injection.
Intervention Type
Drug
Intervention Name(s)
Placebo
Intervention Description
Olezarsen-matching placebo will be administered by SC injection.
Primary Outcome Measure Information:
Title
Percent Change From Baseline to Week 25 in Fasting Triglycerides (TG) Compared to Placebo
Time Frame
Baseline to Week 25
Secondary Outcome Measure Information:
Title
Percent Change From Baseline to Week 53 in Fasting TG Compared to Placebo
Time Frame
Baseline to Week 53
Title
Proportion of Participants who Achieve Fasting TG <150 Milligrams per Deciliter (mg/dL) at Weeks 25 and 53 Compared to Placebo
Time Frame
Baseline, Weeks 25 and 53
Title
Percent Change From Baseline to Weeks 25 and 53 in Fasting Apolipoprotein C-III (apoC-III) Compared to Placebo
Time Frame
Baseline to Weeks 25 and 53
Title
Percent Change From Baseline to Weeks 25 and 53 in Fasting Very Low-Density Lipoprotein-Cholesterol (VLDL)-C Compared to Placebo
Time Frame
Baseline to Weeks 25 and 53
Title
Percent Change From Baseline to Weeks 25 and 53 in Fasting Remnant Cholesterol Compared to Placebo
Time Frame
Baseline to Weeks 25 and 53
Title
Percent Change From Baseline to Weeks 25 and 53 in Fasting non-High Density Lipoprotein-Cholesterol (HDL)-C Compared to Placebo
Time Frame
Baseline to Weeks 25 and 53
Title
Percent Change From Baseline to Weeks 25 and 53 in Fasting High-Density Lipoprotein-Cholesterol (HDL)-C Compared to Placebo
Time Frame
Baseline to Weeks 25 and 53
Title
Percent Change From Baseline to Weeks 25 and 53 in Fasting Total Cholesterol (TC) Compared to Placebo
Time Frame
Baseline to Weeks 25 and 53
Title
Percent Change From Baseline to Weeks 25 and 53 in Fasting Apolipoprotein B (apoB) Compared to Placebo
Time Frame
Baseline to Weeks 25 and 53
Title
Percent Change From Baseline to Weeks 25 and 53 in Fasting Apolipoprotein B-48 (apoB-48) Compared to Placebo
Time Frame
Baseline to Weeks 25 and 53
Title
Percent Change From Baseline to Weeks 25 and 53 in Fasting Low-Density Lipoprotein-Cholesterol (LDL)-C Compared to Placebo
Time Frame
Baseline to Weeks 25 and 53
Title
Percent Change From Baseline to Weeks 25 and 53 in Fasting Apolipoprotein A-1 (apoA-1) Compared to Placebo
Time Frame
Baseline to Weeks 25 and 53
Title
Adjudicated Acute Pancreatitis Event Rate During the Treatment Period Compared to Placebo in Participants With ≥ 2 Events of Adjudicated Acute Pancreatitis in 5 Years Prior to Enrollment
Time Frame
Week 1 through Week 53
Title
Adjudicated Acute Pancreatitis Event Rate from Week 13 to Week 53 Compared to Placebo in Participants With ≥ 2 Events of Adjudicated Acute Pancreatitis in 5 Years Prior to Enrollment
Time Frame
Week 13 through Week 53
Title
Adjudicated Acute Pancreatitis Event Rate During the Treatment Period Compared to Placebo
Time Frame
Week 1 through Week 53
Title
Adjudicated Acute Pancreatitis Event Rate from Week 13 to Week 53 Compared to Placebo
Time Frame
Week 13 through Week 53

10. Eligibility

Sex
All
Minimum Age & Unit of Time
18 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria: Participants must fall into 1 of the following groups (a or b): a. Hypertriglyceridemia with fasting TG ≥200 mg/dL (2.26 millimoles per liter [mmol/L]) and <500 mg/dL (5.65 mmol/L) with either Clinical diagnosis of atherosclerotic cardiovascular disease (ASCVD) or At increased risk for ASCVD b. Severe hypertriglyceridemia with fasting TG ≥500 mg/dL (5.65 mmol/L) Participants should be on standard of care (SOC) lipid-lowering medications per local guidelines. Lipid-lowering medications should be optimized and stabilized for at least 4 weeks prior to Screening to minimize changes in these medications during the study. Exclusion Criteria: Hemoglobin A1c (HbA1c) ≥ 9.5% at Screening Alanine aminotransferase or aspartate aminotransferase > 3.0 × upper limit of normal Total bilirubin > 1.5 upper limit of normal unless due to Gilbert's syndrome Estimated GFR < 30 mL/min/1.73 m^2 NOTE: Other Inclusion/Exclusion criteria may apply.
Central Contact Person:
First Name & Middle Initial & Last Name or Official Title & Degree
Ionis Pharmaceuticals
Phone
(844) 311-2256
Email
IonisCardiovascularDiseaseStudy2@clinicaltrialmedia.com
Facility Information:
Facility Name
Alabama Clinical Therapeutics, LLC Alabaster
City
Birmingham
State/Province
Alabama
ZIP/Postal Code
35235
Country
United States
Individual Site Status
Recruiting
Facility Name
Heart Center Research PC
City
Huntsville
State/Province
Alabama
ZIP/Postal Code
35801
Country
United States
Individual Site Status
Recruiting
Facility Name
Cardiovascular Research Foundation of Southern California
City
Beverly Hills
State/Province
California
ZIP/Postal Code
90210
Country
United States
Individual Site Status
Recruiting
Facility Name
Westside Medical Associates of Los Angeles
City
Beverly Hills
State/Province
California
ZIP/Postal Code
90211
Country
United States
Individual Site Status
Recruiting
Facility Name
Diabetes/Lipid Management & Research Center
City
Huntington Beach
State/Province
California
ZIP/Postal Code
92648
Country
United States
Individual Site Status
Recruiting
Facility Name
University of California, San Diego (UCSD)
City
La Jolla
State/Province
California
ZIP/Postal Code
92037
Country
United States
Individual Site Status
Recruiting
Facility Name
Clinical Trials Research
City
Lincoln
State/Province
California
ZIP/Postal Code
95648
Country
United States
Individual Site Status
Recruiting
Facility Name
Amicis Research
City
Northridge
State/Province
California
ZIP/Postal Code
91324
Country
United States
Individual Site Status
Recruiting
Facility Name
Valley Clinical Trials, Inc.
City
Northridge
State/Province
California
ZIP/Postal Code
91325
Country
United States
Individual Site Status
Recruiting
Facility Name
Northern California Research
City
Sacramento
State/Province
California
ZIP/Postal Code
95821
Country
United States
Individual Site Status
Recruiting
Facility Name
Amicis Research Center
City
Santa Clarita
State/Province
California
ZIP/Postal Code
91344
Country
United States
Individual Site Status
Recruiting
Facility Name
Metabolic Institute of America
City
Tarzana
State/Province
California
ZIP/Postal Code
91356
Country
United States
Individual Site Status
Recruiting
Facility Name
Lundquist Institute for Biomedical Innovation at Harbor UCLA Medical Center
City
Torrance
State/Province
California
ZIP/Postal Code
90502
Country
United States
Individual Site Status
Recruiting
Facility Name
Amicis Research Center
City
Valencia
State/Province
California
ZIP/Postal Code
91355
Country
United States
Individual Site Status
Recruiting
Facility Name
Excel Clinical Medical Trials
City
Boca Raton
State/Province
Florida
ZIP/Postal Code
33434
Country
United States
Individual Site Status
Recruiting
Facility Name
Finlay Medical Research - West Palm
City
Greenacres City
State/Province
Florida
ZIP/Postal Code
33467
Country
United States
Individual Site Status
Recruiting
Facility Name
Global Research Associates
City
Homestead
State/Province
Florida
ZIP/Postal Code
33030
Country
United States
Individual Site Status
Recruiting
Facility Name
3Sync Research
City
Lake Worth
State/Province
Florida
ZIP/Postal Code
33460
Country
United States
Individual Site Status
Recruiting
Facility Name
Finlay Medical Research
City
Miami
State/Province
Florida
ZIP/Postal Code
33126
Country
United States
Individual Site Status
Recruiting
Facility Name
Advanced Medical Research Institute (AMRI)
City
Miami
State/Province
Florida
ZIP/Postal Code
33174
Country
United States
Individual Site Status
Recruiting
Facility Name
De La Cruz Research Center, LL
City
Miami
State/Province
Florida
ZIP/Postal Code
33184
Country
United States
Individual Site Status
Recruiting
Facility Name
Suncoast Clinical Research, Inc. - New Port Richey
City
New Port Richey
State/Province
Florida
ZIP/Postal Code
34652
Country
United States
Individual Site Status
Recruiting
Facility Name
Suncoast Clinical Research, Inc. - Palm Harbor
City
New Port Richey
State/Province
Florida
ZIP/Postal Code
34652
Country
United States
Individual Site Status
Recruiting
Facility Name
Proactive Clinical Research
City
Oakland Park
State/Province
Florida
ZIP/Postal Code
33309
Country
United States
Individual Site Status
Recruiting
Facility Name
Ocala Cardiovascular Research
City
Ocala
State/Province
Florida
ZIP/Postal Code
34471
Country
United States
Individual Site Status
Recruiting
Facility Name
Comprehensive Medical & Research Center
City
Plantation
State/Province
Florida
ZIP/Postal Code
33317
Country
United States
Individual Site Status
Recruiting
Facility Name
Progressive Medical Research
City
Port Orange
State/Province
Florida
ZIP/Postal Code
32127
Country
United States
Individual Site Status
Recruiting
Facility Name
St. Johns Center for Clinical Research
City
Saint Augustine
State/Province
Florida
ZIP/Postal Code
32086
Country
United States
Individual Site Status
Recruiting
Facility Name
JSV Clinical Research Study, Inc
City
Tampa
State/Province
Florida
ZIP/Postal Code
33634
Country
United States
Individual Site Status
Recruiting
Facility Name
Centricity Research
City
Columbus
State/Province
Georgia
ZIP/Postal Code
31904
Country
United States
Individual Site Status
Recruiting
Facility Name
Atlanta Heart Specialists
City
Tucker
State/Province
Georgia
ZIP/Postal Code
30084
Country
United States
Individual Site Status
Recruiting
Facility Name
Evanston Premier Healthcare Research LLC
City
Evanston
State/Province
Illinois
ZIP/Postal Code
60201
Country
United States
Individual Site Status
Recruiting
Facility Name
Clinical Investigation Specialists, Inc
City
Gurnee
State/Province
Illinois
ZIP/Postal Code
60031
Country
United States
Individual Site Status
Recruiting
Facility Name
Affinity Health
City
Park Ridge
State/Province
Illinois
ZIP/Postal Code
60068
Country
United States
Individual Site Status
Recruiting
Facility Name
Cardiovascular Research of Northwest Indiana, LLC
City
Munster
State/Province
Indiana
ZIP/Postal Code
46321
Country
United States
Individual Site Status
Recruiting
Facility Name
Reid Hospital and Health Care Services
City
Richmond
State/Province
Indiana
ZIP/Postal Code
47374
Country
United States
Individual Site Status
Recruiting
Facility Name
West Broadway Clinic
City
Council Bluffs
State/Province
Iowa
ZIP/Postal Code
51501
Country
United States
Individual Site Status
Recruiting
Facility Name
Mercy One Iowa Heart Center
City
West Des Moines
State/Province
Iowa
ZIP/Postal Code
50266
Country
United States
Individual Site Status
Recruiting
Facility Name
University of Kansas Medical Center (KUMC)
City
Kansas City
State/Province
Kansas
ZIP/Postal Code
66160
Country
United States
Individual Site Status
Recruiting
Facility Name
Norton Cardiovascular Associates
City
Louisville
State/Province
Kentucky
ZIP/Postal Code
40205
Country
United States
Individual Site Status
Recruiting
Facility Name
Louisville Metabolic and Atherosclerosis Research Center
City
Louisville
State/Province
Kentucky
ZIP/Postal Code
40213
Country
United States
Individual Site Status
Recruiting
Facility Name
Maryland Cardiovascular Specialists
City
Baltimore
State/Province
Maryland
ZIP/Postal Code
21229
Country
United States
Individual Site Status
Recruiting
Facility Name
Aa Mrc, Llc
City
Flint
State/Province
Michigan
ZIP/Postal Code
48504
Country
United States
Individual Site Status
Recruiting
Facility Name
Palm Research Center, Inc.
City
Las Vegas
State/Province
Nevada
ZIP/Postal Code
49148
Country
United States
Individual Site Status
Recruiting
Facility Name
Clinical Research of South Nevada
City
Las Vegas
State/Province
Nevada
ZIP/Postal Code
89104
Country
United States
Individual Site Status
Recruiting
Facility Name
Palm Research Center, Inc.
City
Las Vegas
State/Province
Nevada
ZIP/Postal Code
89148
Country
United States
Individual Site Status
Recruiting
Facility Name
Medical University of South Carolina (MUSC)
City
Charleston
State/Province
North Carolina
ZIP/Postal Code
29425
Country
United States
Individual Site Status
Recruiting
Facility Name
Moses H. Cone Memorial Hospital
City
Greensboro
State/Province
North Carolina
ZIP/Postal Code
27401
Country
United States
Individual Site Status
Recruiting
Facility Name
Aultman Hospital Cardiology Clinical Trials
City
Canton
State/Province
Ohio
ZIP/Postal Code
44710
Country
United States
Individual Site Status
Recruiting
Facility Name
McConnell Heart Health Center
City
Columbus
State/Province
Ohio
ZIP/Postal Code
43214
Country
United States
Individual Site Status
Recruiting
Facility Name
Summit Research Group, LLC
City
Stow
State/Province
Ohio
ZIP/Postal Code
44224
Country
United States
Individual Site Status
Recruiting
Facility Name
Central Oklahoma Early Detection Center
City
Edmond
State/Province
Oklahoma
ZIP/Postal Code
73034
Country
United States
Individual Site Status
Recruiting
Facility Name
Green and Seidner Family Practice Associates
City
Lansdale
State/Province
Pennsylvania
ZIP/Postal Code
19446
Country
United States
Individual Site Status
Recruiting
Facility Name
Main Street Physicians Care Waterway
City
Little River
State/Province
South Carolina
ZIP/Postal Code
29566
Country
United States
Individual Site Status
Recruiting
Facility Name
OnSite Clinical Solutions, LLC
City
Rock Hill
State/Province
South Carolina
ZIP/Postal Code
29732
Country
United States
Individual Site Status
Recruiting
Facility Name
Monument Health Clinical Research
City
Rapid City
State/Province
South Dakota
ZIP/Postal Code
57701
Country
United States
Individual Site Status
Recruiting
Facility Name
Health Concepts
City
Rapid City
State/Province
South Dakota
ZIP/Postal Code
57702
Country
United States
Individual Site Status
Recruiting
Facility Name
The Jackson Clinic
City
Jackson
State/Province
Tennessee
ZIP/Postal Code
38301
Country
United States
Individual Site Status
Recruiting
Facility Name
Affinity Health Corp.
City
Nashville
State/Province
Tennessee
ZIP/Postal Code
37203
Country
United States
Individual Site Status
Recruiting
Facility Name
Tennessee Center for Clinical Trials
City
Tullahoma
State/Province
Tennessee
ZIP/Postal Code
37388
Country
United States
Individual Site Status
Recruiting
Facility Name
Baylor College of Medicine
City
Houston
State/Province
Texas
ZIP/Postal Code
77030
Country
United States
Individual Site Status
Recruiting
Facility Name
Juno Research, LLC
City
Houston
State/Province
Texas
ZIP/Postal Code
77040
Country
United States
Individual Site Status
Recruiting
Facility Name
Texas Institute of Cardiology
City
McKinney
State/Province
Texas
ZIP/Postal Code
75071
Country
United States
Individual Site Status
Recruiting
Facility Name
Southern Endocrinology Associates
City
Mesquite
State/Province
Texas
ZIP/Postal Code
75149
Country
United States
Individual Site Status
Recruiting
Facility Name
FMC Science
City
Round Rock
State/Province
Texas
ZIP/Postal Code
78681
Country
United States
Individual Site Status
Recruiting
Facility Name
Carient Heart & Vascular
City
Manassas
State/Province
Virginia
ZIP/Postal Code
20109
Country
United States
Individual Site Status
Recruiting
Facility Name
Manassas Clinical Research Center
City
Manassas
State/Province
Virginia
ZIP/Postal Code
20110
Country
United States
Individual Site Status
Recruiting
Facility Name
Charleston Area Medical Center (CAMC) Clinical Trials Center
City
Charleston
State/Province
West Virginia
ZIP/Postal Code
25304
Country
United States
Individual Site Status
Recruiting
Facility Name
University Multiprofile Hospital for Active Treatment Pulmed OOD
City
Plovdiv
ZIP/Postal Code
4000
Country
Bulgaria
Individual Site Status
Recruiting
Facility Name
SHATC Medica Cor EAD
City
Ruse
ZIP/Postal Code
7013
Country
Bulgaria
Individual Site Status
Recruiting
Facility Name
Medical Center for Specialized Medical Help in Cardiovascular Diseases OOD
City
Sofia
ZIP/Postal Code
1000
Country
Bulgaria
Individual Site Status
Recruiting
Facility Name
MBAL National Cardiology Hospital
City
Sofia
ZIP/Postal Code
1309
Country
Bulgaria
Individual Site Status
Recruiting
Facility Name
University Multiprofile Hospital for Active Treatment
City
Sofia
ZIP/Postal Code
1431
Country
Bulgaria
Individual Site Status
Recruiting
Facility Name
Medico Dental Center ISUL Tsaritsa Yoanna EOOD
City
Sofia
ZIP/Postal Code
1527
Country
Bulgaria
Individual Site Status
Recruiting
Facility Name
UMHAT Prof. Dr. Stoyan Kirkovich
City
Stara Zagora
ZIP/Postal Code
6003
Country
Bulgaria
Individual Site Status
Recruiting
Facility Name
Diagnostic Consultative Center Equita (DCC Equita)
City
Varna
ZIP/Postal Code
9000
Country
Bulgaria
Individual Site Status
Recruiting
Facility Name
Specialized Hospital for Active Treatment of Cardiology
City
Varna
ZIP/Postal Code
9020
Country
Bulgaria
Individual Site Status
Recruiting
Facility Name
ARC Biosystems
City
Vancouver
State/Province
British Columbia
ZIP/Postal Code
V6Z 2C7
Country
Canada
Individual Site Status
Recruiting
Facility Name
Centricity Research - Vaughan Endocrinology
City
Concord
State/Province
Ontario
ZIP/Postal Code
L4K 4M2
Country
Canada
Individual Site Status
Recruiting
Facility Name
Centricity Research - Etobicoke Endocrinology
City
Etobicoke
State/Province
Ontario
ZIP/Postal Code
M9R 4E1
Country
Canada
Individual Site Status
Recruiting
Facility Name
Centricity Research - Oshawa Multispecialty
City
Oshawa
State/Province
Ontario
ZIP/Postal Code
L1J 2K9
Country
Canada
Individual Site Status
Recruiting
Facility Name
Bluewater Clinical Research Group Inc
City
Sarnia
State/Province
Ontario
ZIP/Postal Code
N7t 4X3
Country
Canada
Individual Site Status
Recruiting
Facility Name
Centricity Research - Toronto LMC Multispecialty
City
Toronto
State/Province
Ontario
ZIP/Postal Code
M4G 3E8
Country
Canada
Individual Site Status
Recruiting
Facility Name
Ecogene-21
City
Chicoutimi
State/Province
Quebec
ZIP/Postal Code
G7H 7K9
Country
Canada
Individual Site Status
Recruiting
Facility Name
Institute de Recherches Cliniques de Montreal
City
Montréal
State/Province
Quebec
ZIP/Postal Code
H2W 1R7
Country
Canada
Individual Site Status
Recruiting
Facility Name
Clinique des Maladies Lipidiques de Quebec Inc.
City
Québec
State/Province
Quebec
ZIP/Postal Code
G1V 4W2
Country
Canada
Individual Site Status
Recruiting
Facility Name
Centricity Research - Barrie Endocrinology
City
Barrie
ZIP/Postal Code
L4N 7L3
Country
Canada
Individual Site Status
Recruiting
Facility Name
Centricity Research - Brampton Endocrinology
City
Brampton
ZIP/Postal Code
L6S 6J6
Country
Canada
Individual Site Status
Recruiting
Facility Name
Centre de Recherche Saint-Louis
City
Québec
ZIP/Postal Code
G1W 4R4
Country
Canada
Individual Site Status
Recruiting
Facility Name
UNIVMED s.r.o. - Kardiologicka Ambulance
City
Brno
ZIP/Postal Code
60300
Country
Czechia
Individual Site Status
Recruiting
Facility Name
Edumed s.r.o., Kardiologicka, endokrinologicka, diabetologicka a interni ambulance Nachod
City
Jaroměř
ZIP/Postal Code
551 01
Country
Czechia
Individual Site Status
Recruiting
Facility Name
Endokrinologie Cerny Most s.r.o.
City
Prague
ZIP/Postal Code
19800
Country
Czechia
Individual Site Status
Recruiting
Facility Name
Affidea Praha s.r.o.
City
Praha
ZIP/Postal Code
148 00
Country
Czechia
Individual Site Status
Recruiting
Facility Name
Diabetologicka a endokrinologicka ambulance Milan Kvapil s.r.o
City
Praha
ZIP/Postal Code
149 00
Country
Czechia
Individual Site Status
Recruiting
Facility Name
AeskuLab k.s
City
Teplice
ZIP/Postal Code
415 01
Country
Czechia
Individual Site Status
Recruiting
Facility Name
MUDr. Nina Zemkova s.r.o. Interni Ambulance
City
Uherske Hradiste
ZIP/Postal Code
686 68
Country
Czechia
Individual Site Status
Recruiting
Facility Name
Aarhus University Hospital
City
Aarhus
ZIP/Postal Code
8000
Country
Denmark
Individual Site Status
Recruiting
Facility Name
Sydvestjysk Hospital
City
Esbjerg
ZIP/Postal Code
6700
Country
Denmark
Individual Site Status
Recruiting
Facility Name
Gentofte Hospital
City
Hellerup
ZIP/Postal Code
2900
Country
Denmark
Individual Site Status
Recruiting
Facility Name
Godstrup Regional Hospital (Gødstrup)
City
Herning
ZIP/Postal Code
7400
Country
Denmark
Individual Site Status
Recruiting
Facility Name
OUH Svendborg Hospital
City
Svendborg
ZIP/Postal Code
5700
Country
Denmark
Individual Site Status
Recruiting
Facility Name
Viborg Regional Hospital
City
Viborg
ZIP/Postal Code
8800
Country
Denmark
Individual Site Status
Recruiting
Facility Name
HCL Hopital Louis Pradel
City
Bron
ZIP/Postal Code
69677
Country
France
Individual Site Status
Recruiting
Facility Name
CHU Dijon Bourgogne - Hopital Francois Mitterrand
City
Dijon
ZIP/Postal Code
21000
Country
France
Individual Site Status
Recruiting
Facility Name
AP-HP Hopital Pitie-Salpetriere
City
Paris
ZIP/Postal Code
75013
Country
France
Individual Site Status
Recruiting
Facility Name
Groupement de Cooperation Sanitaire (GCS) ELSAN - Polyclinique Vauban
City
Valenciennes
ZIP/Postal Code
59300
Country
France
Individual Site Status
Recruiting
Facility Name
GHM les Portes du Sud
City
Vénissieux
ZIP/Postal Code
69200
Country
France
Individual Site Status
Recruiting
Facility Name
Clinexpert Kft.
City
Budapest
ZIP/Postal Code
1033
Country
Hungary
Individual Site Status
Recruiting
Facility Name
Obudai Egeszsegugyi Centrum
City
Budapest
ZIP/Postal Code
H-1036
Country
Hungary
Individual Site Status
Recruiting
Facility Name
CRU Hungary Kft.
City
Encs
ZIP/Postal Code
H-3860
Country
Hungary
Individual Site Status
Recruiting
Facility Name
ASST NORD MILANO-Ospedale Edoardo Bassini
City
Cinisello Balsamo
ZIP/Postal Code
20092
Country
Italy
Individual Site Status
Recruiting
Facility Name
Azienda Ospedaliero-Universitaria di Ferrara-Arcispedale Sant'Anna
City
Cona
ZIP/Postal Code
44124
Country
Italy
Individual Site Status
Recruiting
Facility Name
Centro Cardiologico Monzino
City
Milano
ZIP/Postal Code
20138
Country
Italy
Individual Site Status
Recruiting
Facility Name
ASST Grande Ospedale Metropolitano Niguarda
City
Milano
ZIP/Postal Code
20162
Country
Italy
Individual Site Status
Recruiting
Facility Name
Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone
City
Palermo
ZIP/Postal Code
90127
Country
Italy
Individual Site Status
Recruiting
Facility Name
Fondazione Policlinico Universitario A. Gemelli IRCCS - Universita Cattolica del Sacro Cuore
City
Rome
ZIP/Postal Code
168
Country
Italy
Individual Site Status
Recruiting
Facility Name
Academic Medical Center - Department of Vascular Medicine
City
Amsterdam
ZIP/Postal Code
1105AZ
Country
Netherlands
Individual Site Status
Recruiting
Facility Name
Ziekenhuis Rijnstate
City
Arnhem
ZIP/Postal Code
6815 AD
Country
Netherlands
Individual Site Status
Recruiting
Facility Name
Reinier de Graaf Gasthuis
City
Delft
ZIP/Postal Code
2625 AD
Country
Netherlands
Individual Site Status
Recruiting
Facility Name
Deventer Ziekenhuis
City
Deventer
ZIP/Postal Code
7416 SE
Country
Netherlands
Individual Site Status
Recruiting
Facility Name
Het Van Weel-Bethesda Ziekenhuis
City
Dirksland
ZIP/Postal Code
3247 BW
Country
Netherlands
Individual Site Status
Recruiting
Facility Name
Groene Hart Ziekenhuis
City
Gouda
ZIP/Postal Code
2803 HH
Country
Netherlands
Individual Site Status
Recruiting
Facility Name
Spaarne Gasthuis
City
Haarlem
ZIP/Postal Code
2035 RC
Country
Netherlands
Individual Site Status
Recruiting
Facility Name
Zuyderland Medisch Centrum
City
Heerlen
ZIP/Postal Code
6419 PC
Country
Netherlands
Individual Site Status
Recruiting
Facility Name
Bethesda Diabetes Research Center
City
Hoogeveen
ZIP/Postal Code
7909 AA
Country
Netherlands
Individual Site Status
Recruiting
Facility Name
Canisius-Wilhelmina Ziekenhuis (CWZ)
City
Nijmegen
ZIP/Postal Code
6532 SZ
Country
Netherlands
Individual Site Status
Recruiting
Facility Name
D&A Research
City
Sneek
ZIP/Postal Code
8601 ZR
Country
Netherlands
Individual Site Status
Recruiting
Facility Name
Universitair Medisch Centrum Utrecht
City
Utrecht
ZIP/Postal Code
3584 CX
Country
Netherlands
Individual Site Status
Recruiting
Facility Name
Maxima Medisch Centrum
City
Veldhoven
ZIP/Postal Code
5504 DB
Country
Netherlands
Individual Site Status
Recruiting
Facility Name
Albert Schweitzer Ziekenhuis - Location Dordrecht
City
Zwijndrecht
ZIP/Postal Code
3331 LZ
Country
Netherlands
Individual Site Status
Recruiting
Facility Name
The Lipid Clinic (Oslo University Hospital)
City
Oslo
ZIP/Postal Code
424
Country
Norway
Individual Site Status
Recruiting
Facility Name
SALVIA Lekston i Madej s.j.
City
Katowice
ZIP/Postal Code
40-772
Country
Poland
Individual Site Status
Recruiting
Facility Name
Krakowskie Centrum Medyczne Sp. z o.o.
City
Krakow
ZIP/Postal Code
31-501
Country
Poland
Individual Site Status
Recruiting
Facility Name
Jagiellonskie Centrum Innowacji Sp. z o.o.
City
Kraków
ZIP/Postal Code
30-348
Country
Poland
Individual Site Status
Recruiting
Facility Name
Praktyka Lekarska Ewa Krzyzagorska
City
Poznań
ZIP/Postal Code
61-655
Country
Poland
Individual Site Status
Recruiting
Facility Name
Clinical Best Solutions Sp. z.o.o Spolka Komandytowa
City
Warsaw
ZIP/Postal Code
00-710
Country
Poland
Individual Site Status
Recruiting
Facility Name
Narodowy Instytut Kardiologii Stefana kardynala Wyszynskiego - Panstwowy Instytut Badawczy, Klinika Kardiologii i Angiologii Interwencyjnej
City
Warsaw
ZIP/Postal Code
04-628
Country
Poland
Individual Site Status
Recruiting
Facility Name
FutureMeds Warszawa Centrum
City
Warszawa
ZIP/Postal Code
00-215
Country
Poland
Individual Site Status
Recruiting
Facility Name
FutureMeds - Centrum Medyczne AMED Warszawa Targowek
City
Warszawa
ZIP/Postal Code
03-291
Country
Poland
Individual Site Status
Recruiting
Facility Name
FutureMeds Sp. z o.o
City
Wrocław
ZIP/Postal Code
50-088
Country
Poland
Individual Site Status
Recruiting
Facility Name
Slaski Park Technologii Medycznych Kardio-Med Silesia Sp. z o. o
City
Zabrze
ZIP/Postal Code
48-100
Country
Poland
Individual Site Status
Recruiting
Facility Name
FutureMeds
City
Łódź
ZIP/Postal Code
91-363
Country
Poland
Individual Site Status
Recruiting
Facility Name
INSTYTUT CENTRUM ZDROWIA MATKI POLKI - Klinika Kardiologii i Wad Wrodzonych Doroslych
City
Łódź
ZIP/Postal Code
93-338
Country
Poland
Individual Site Status
Recruiting
Facility Name
Centro Hospitalar de Lisboa Ocidental. E.P.E, - Hospital Santa Cruz
City
Carnaxide
ZIP/Postal Code
2790-134
Country
Portugal
Individual Site Status
Recruiting
Facility Name
Centro Hospitalar de Lisboa Ocidental, EPE - Hospital Egas Moniz
City
Lisboa
ZIP/Postal Code
1349-019
Country
Portugal
Individual Site Status
Recruiting
Facility Name
Centro Hospitalar Universitario de Lisboa Norte - Hospital de Santa Maria
City
Lisboa
ZIP/Postal Code
1649-036
Country
Portugal
Individual Site Status
Recruiting
Facility Name
Centro Hospitalar de Vila Nova de Gaia/Espinho EPE
City
Vila Nova de Gaia
ZIP/Postal Code
4434-502
Country
Portugal
Individual Site Status
Recruiting
Facility Name
Alian, s.r.o., Kardiologicka ambulancia
City
Bardejov
ZIP/Postal Code
085 01
Country
Slovakia
Individual Site Status
Recruiting
Facility Name
Cardio D&R, S.R.O. Kosice
City
Kosice
ZIP/Postal Code
040 22
Country
Slovakia
Individual Site Status
Recruiting
Facility Name
Diab sro
City
Roznava
ZIP/Postal Code
048 01
Country
Slovakia
Individual Site Status
Recruiting
Facility Name
Interna SK, s.r.o., Kardiologicka a interna ambulancia
City
Svidnik
ZIP/Postal Code
8901
Country
Slovakia
Individual Site Status
Recruiting
Facility Name
Hospital de la Santa Creu i Sant Pau
City
Barcelona
ZIP/Postal Code
8025
Country
Spain
Individual Site Status
Recruiting
Facility Name
Calle Villarroel 170
City
Barcelona
ZIP/Postal Code
8036
Country
Spain
Individual Site Status
Recruiting
Facility Name
Hospital Universitario Reina Sofia
City
Córdoba
ZIP/Postal Code
14004
Country
Spain
Individual Site Status
Recruiting
Facility Name
Hospital Clinico Universitario Virgen de la Arrixaca
City
El Palmar
ZIP/Postal Code
30120
Country
Spain
Individual Site Status
Recruiting
Facility Name
Hospital Abente y Lago
City
La Coruna
ZIP/Postal Code
15001
Country
Spain
Individual Site Status
Recruiting
Facility Name
Hospital Clinico San Carlos
City
Madrid
ZIP/Postal Code
28040
Country
Spain
Individual Site Status
Recruiting
Facility Name
Hospital Universitario Virgen de la Victoria
City
Málaga
ZIP/Postal Code
29010
Country
Spain
Individual Site Status
Recruiting
Facility Name
Hospital Universitario Virgen Macarena
City
Sevilla
ZIP/Postal Code
41009
Country
Spain
Individual Site Status
Recruiting

12. IPD Sharing Statement

Plan to Share IPD
No

Learn more about this trial

A Study of Olezarsen (ISIS 678354) in Participants With Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease, or With Severe Hypertriglyceridemia

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