A Study to Assess if Scratching the Lining of the Womb Prior to IVF Treatment Increases the Chances of Pregnancy
Infertility
About this trial
This is an interventional treatment trial for Infertility focused on measuring Infertility, Endometrium, Live birth
Eligibility Criteria
Inclusion Criteria:
- Women with history of primary or secondary infertility undergoing fresh IVF/ ICSI treatment or frozen embryo replacement cycle
- Age <49
Exclusion Criteria:
- Non- ovulatory cycles
- Absent uterus
- Uterine instrumentation within previous 3 menstrual cycles
- Women in the oocyte donation program
Sites / Locations
- Nurture Fertility
Arms of the Study
Arm 1
Arm 2
Experimental
No Intervention
Endometrial biopsy arm
Control group
Participants randomised to this arm arm will undergo an endometrial biopsy procedure using Pipelle endometrial sampler (Pipelle de Cornier, Laboratoire CCD, Paris, France) or Wallace/ Wallach endometrial sampler as an alternative device on cycle day LH+7 to LH+9 of the cycle directly preceding commencement of down-regulation prior to IVF or ICSI treatment. A transvaginal ultrasound scan will be performed prior to the biopsy.
Participants randomised to control group will undergo a transvaginal ultrasound scan on day LH+7 to LH+9 of the cycle directly preceding commencement of IVF/ICSI treatment.