A Study To Assess The Efficacy and Safety of HH-120 Nasal Spray for the Treatment of Mild COVID-19
COVID-19
About this trial
This is an interventional treatment trial for COVID-19
Eligibility Criteria
Inclusion Criteria: Participants who are ≥18 years of age . Participants who are diagnosed with mild COVID-19 and with Laboratory confirmed of SARS-CoV-2 infection as determined by PCR or antigen test. Participants who agree to use highly effective methods of contraception. Women of childbearing potential (WOCBP) must have a negative urine pregnancy test result. Participants who are willing and able to provide written informed consent, or with a legal representative who can provide informed consent. Exclusion Criteria: Have suspected or proven serious disease (cardiovascular, renal, liver systems, etc.), active bacterial, fungal, viral, or other infection (except COVID 19) that in the opinion of the Investigator could constitute a risk when taking the study intervention. Bronchial asthma or chronic obstructive pulmonary disease (COPD). Urgent or expected need for nasal high-flow oxygen therapy or positive pressure ventilation, invasive mechanical ventilation or Extracorporeal membrane oxygenation(ECMO). Have prior use (unless required as rescue medication) of any of the following treatments: COVID 19 investigational or Emergency Use Authorization (EUA) approved treatment, including but not limited to convalescent plasma, mAbs against SARS CoV 2, intravenous immune globulin (IVIG) (any indication), where prior use is defined as the past 30 days or less than 5 half lives of the investigational product (whichever is longer) from Screening. History of anaphylaxis or other significant allergy in the opinion of the PI or known allergy or hypersensitivity to any of the components of the study intervention.
Sites / Locations
- Beijing Ditan Hospital, Capital Medical UniversityRecruiting
- Beijing Friendship Hospital,Capital Medical UniversityRecruiting
- Peking University Third HospitalRecruiting
- Mengchao Hepatobiliary Hospital Of Fujian Medical UniversityRecruiting
- The People's Hospital of GaozhouRecruiting
- Nanfang Hospital,Southern Medical UniversityRecruiting
- Xiangtan Central HospitalRecruiting
- Lianyungang Oriental HospitalRecruiting
- Yixing People's HospitalRecruiting
- The First Hospital of Jilin UniversityRecruiting
- Panjin Liaoyou Gem flower HospitalRecruiting
- Linfen Central HospitalRecruiting
- Chengdu Second People's HospitalRecruiting
- Qujing First People's HospitalRecruiting
- Southern Central Hospital Of Yunnan Province(The First People's Hospital Of Honghe State)Recruiting
- Wenzhou Traditional Chinese Medicine HospitalRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Experimental
Experimental
Placebo Comparator
Placebo Comparator
Treatment Group 1
Treatment Group 2
Control Group 3
Control Group 4