A Study to Compare Two Anti-HIV Combination Therapies Each Containing Saquinavir in HIV-Positive Children
HIV Infections
About this trial
This is an interventional treatment trial for HIV Infections focused on measuring Saquinavir, Reverse Transcriptase Inhibitors, Anti-HIV Agents, Viral Load
Eligibility Criteria
Inclusion Criteria Your child may be eligible for this study if he or she: Is HIV-positive. Is 3 to 16 years of age (consent of parent or guardian is required). Has an HIV level greater than 10,000 copies/ml. Has never taken at least one of the following anti-HIV drugs: lamivudine, zidovudine, stavudine, or didanosine. Is able to swallow capsules and tablets. Exclusion Criteria Your child will not be eligible if he or she: Has cancer requiring chemotherapy. Has an acute opportunistic (AIDS-related) infection requiring therapy. Has had two or more episodes of moderate or severe diarrhea or vomiting in the 3 months prior to study entry. Has ever taken SQV or NFV. Is pregnant or breast-feeding. Is taking certain medications, including those that would interfere with the study drugs.
Sites / Locations
- Univ of Alabama at Birmingham / Childrens Hosp of AL
- Univ of Alabama at Birmingham - Pediatric
- Long Beach Memorial (Pediatric)
- Los Angeles County - USC Med Ctr
- Children's Hosp of Oakland
- UCSF / Moffitt Hosp - Pediatric
- Yale Univ Med School
- Howard Univ Hosp
- Univ of Miami (Pediatric)
- Palm Beach County Health Dept
- Emory Univ Hosp / Pediatrics
- Cook County Hosp
- Univ of Illinois College of Medicine / Pediatrics
- Chicago Children's Memorial Hosp
- Tulane Univ / Charity Hosp of New Orleans
- Univ of Maryland at Baltimore / Univ Med Ctr
- Children's Hosp of Boston
- Baystate Med Ctr of Springfield
- Univ of Mississippi Med Ctr
- Univ of Medicine & Dentistry of New Jersey / Univ Hosp
- Children's Hosp at Albany Med Ctr
- Bronx Lebanon Hosp Ctr
- Bronx Municipal Hosp Ctr/Jacobi Med Ctr
- North Shore Univ Hosp
- Cornell Univ Med College
- Columbia Presbyterian Med Ctr
- Incarnation Children's Ctr / Columbia Presbyterian Med Ctr
- Harlem Hosp Ctr
- State Univ of New York at Stony Brook
- Saint Christopher's Hosp for Children
- Med Univ of South Carolina
- Med College of Virginia
- Children's Hospital & Medical Center / Seattle ACTU
- Ramon Ruiz Arnau Univ Hosp / Pediatrics
- Univ of Puerto Rico / Univ Children's Hosp AIDS
- San Juan City Hosp