A Study to Evaluate ABP 938 and Aflibercept (Eylea®) in Participants With Chorioretinal Vascular Disease (CVD)

Inclusion Criteria Must sign an IRB approved informed consent form before any study-specific procedures are initiated. Men or women ≥18 years old. Treatment-naïve or previously treated neovascular age-related macular degeneration, diabetic macular edema, macular edema following retinal vein occlusion, or diabetic retinopathy in the study eye. Exclusion Criteria Active intraocular or periocular infection or active intraocular inflammation in either eye. Uncontrolled intraocular pressure greater than (>) 25 mmHg in the study eye. Deemed legally blind in one or both eyes. History of or any current indication of excessive bleeding or recurrent hemorrhages, including any prior excessive intraocular bleeding or hemorrhages after IVT injection or intraocular procedures in either eye. Current systemic infectious disease or on a therapy for active infectious disease. History of any medical, ocular or non-ocular conditions that, in the opinion of the investigator, may interfere with the injection procedure or pose a safety concern. History of stroke or transient ischemic attacks or myocardial infarction within the last 6 months. Treatment with anti-VEGF IVT injection in the study eye within 28 days. Any use of intraocular corticosteroids in the study eye within 3 months. Receipt of any systemic anti-VEGF within the last 6 months. Any invasive intraocular surgery, prior long-acting therapeutic agent, or ocular drug release device implantation in the study eye within the past 3 months. For women: pregnant or breast feeding, or planning to become pregnant while enrolled in the study and for 3 months after IP administration. Sexually active participants and their partners who are of childbearing potential who refuse to use adequate contraception while on-study and for 3 months after IP administration. Male participants must agree not to donate sperm during study and for 3 months following dose of IP. Allergy or hypersensitivity to the IP, to any of the excipients of ABP 938 or aflibercept, or to other study-related procedures/medications. Previously enrolled in this study. Participation in any interventional clinical study within 3 months prior to screening.