A Trial Evaluating the Clinical Applicability, Correlation, and Modeling of Cardiac CT Using 64 Detector Row VCT
Coronary Artery Disease
About this trial
This is an interventional diagnostic trial for Coronary Artery Disease
Eligibility Criteria
Inclusion Criteria: Patients scheduled for elective diagnostic catheterization OR Elective diagnostic catheterization has been performed within the past 2 weeks but no less than 24 hours prior to the coronary CTA procedure with no intervention performed or change of the patient clinical status. Age ≥18 years but ≤75 years. Exclusion Criteria: Prior coronary stent implantation Prior coronary artery bypass grafting or other heart surgery Prior pacemaker or internal defibrillator lead implantation Prior artificial heart valve Biochemical renal insufficiency (CrSerum > 1.6) or on dialysis Resting HR > 100 at the time of enrollment Contraindication to β-blockade or calcium channel blocker NYHA-IV High-grade atrioventricular (AV) block Systolic blood pressure <90 mm Hg Severe asthma or active bronchospasm and/or chronic obstructive pulmonary disease Atrial fibrillation Inability to provide informed consent Evidence of ongoing or active clinical instability Acute chest pain (sudden onset) Acute myocardial infarction Cardiac shock Acute pulmonary edema
Sites / Locations
- GE Healthcare
Arms of the Study
Arm 1
Experimental
64 Channel VCT
All subjects underwent Coronary Computed Tomographic Angiography (CCTA) after receiving an intravenous (IV) administration of Visipaque (320 mgI/mL), to be followed by catheter coronary angiography (CATH).