Back to resultsA Trial of Camrelizumab Combined With Famitinib Malate in Treatment Naïve Subjects With PD-L1-Positive Recurrent or Metastatic Non-Small Cell Lung Cancer
Primary Purpose
Non-small Cell Lung Cancer
Status
Recruiting
Phase
Phase 3
Locations
China
Study Type
Interventional
Intervention
camrelizumab + famitinib
pembrolizumab
camrelizumab
Sponsored by
About this trial
This is an interventional treatment trial for Non-small Cell Lung Cancer
Eligibility Criteria
Inclusion Criteria:
- Have a histologically or cytologically confirmed diagnosis of metastatic NSCLC (stage IV according to the TNM staging criteria [8th edition] published by the International Association for the Study of Lung Cancer [IASLC]), or NSCLC that recurs after curable surgery, radiotherapy, or radiochemotherapy.
- Have measurable disease based on RECIST v1.1.
- ECOG PS score: 0-1.
- Have a life expectancy of at least 3 months.
- Non-surgically sterilized female subjects or women of childbearing potential must be negative for a serum pregnancy test within 3 days prior to the first dose and must be non-lactating. Female subjects of childbearing potential and male subjects with partners of childbearing potential must agree to take highly effective contraceptive measures during the study period and within 6 months after the last dose of study drugs.
- Have voluntarily agreed to participate by giving written informed consent for the study, have good compliance, and cooperate with follow-up visits.
Exclusion Criteria:
- Accompanied with EGFR activating mutation, ALK fusion gene positive or ROS1 mutation.
- Have uncontrolled clinically symptomatic pleural effusion, pericardial effusion, or ascites.
- Have known history of prior malignancy in the past 3 years.
- Have had an allogeneic tissue/solid organ transplant.
- Have active pulmonary tuberculosis.
- Have clinical symptoms of the heart or heart diseases that are not well controlled.
- Have hypertension which cannot be well controlled by antihypertensives
- Urinalysis has indicated that the urine protein is ≥ ++ and quantitative test of urine protein has confirmed that the 24-h urine protein is > 1.0 g.
- Have a thrombosis tendency or are currently receiving thrombolysis/anticoagulation therapy.
- Have received major surgery within 4 weeks prior to randomization; or palliative radiotherapy within 2 weeks prior to randomization; or have not recovered from the toxicities and/or complications of previous interventions to NCI-CTCAE Grade ≤ 1.
- Have known history of arterial/venous thrombosis within 6 months prior to randomization, such as cerebrovascular accidents, deep vein thrombosis and pulmonary embolism.
- Have received prior therapy with anti-PD-1/PD-L1 monoclonal antibodies, anti-CTLA-4 monoclonal antibodies, or small molecule VEGFR inhibitors.
- Have known allergies to other monoclonal antibodies or any component of famitinib.
- Are currently participating and receiving study therapy or have participated in a study and received the last dose of study drug within 4 weeks (or 5 half-lives of the study drug) prior to randomization.
- Have other potential factors that may affect the study results or result in the premature discontinuation as determined by the investigator, such as alcoholism, drug abuse, substance abuse, other serious diseases (including mental illness) requiring concomitant treatment, serious laboratory abnormalities, or family or social factors that could affect the safety of medication.
Sites / Locations
- The First Affiliated Hospital of Bengbu Medical College
- Anhui Chest Hospital
- Anhui Provincial Cancer Hospital
- Anhui Provincial Hospital
- The First Affiliated Hospital Of Anhui Medical University
- Beijing Cancer Hospital
- Beijing Chest Hospital,Capital Medical University
- Peking University Third HospitalRecruiting
- ChongQing University Cancer HospitalRecruiting
- Fujian Medical University Union Hospital
- Fujian Provincial Cancer Hospital
- The First Affiliated Hospital of Xiamen University
- The Second Affiliated Hospital of Xiamen Medical CollegeRecruiting
- The People's Hospital of Gaozhou
- Affiliated Cancer Hospital and Institute of Guangzhou Medical University
- The First Affiliated Hospital of Guangzhou Medical University
- The First Affiliated Hospital of Guangzhou University of Chinese Medicine
- Meizhou People's Hospital (Huangtang Hospital)
- Shantou Central Hospital
- Affiliated Hospital of Guangdong Medical University
- Affiliated Hospital of Guilin Medical University
- Guangxi Medical University Affiliated Tumor Hospital
- The First Affiliated Hospital of Guangxi Medical University
- Affiliated Hospital of Zunyi Medical University
- Hainan General Hospital
- The Fourth Hospital of Hebei Medical University
- North China University Of Science And Technology Affiliated Hospital
- Xingtai People's Hospital
- Haerbin Medical University Cancer Hospital
- Anyang Cancer HospitalRecruiting
- The First Affiliated Hosptial of Henan University of Science & TechnologyRecruiting
- Henan Cancer Hospital
- The First Affiliated Hospital of Zhengzhou UniversityRecruiting
- Shiyan Taihe Hospital
- Union Hospital Tongji Medical College Huazhong University of Science and Technology
- Xiangyang Central HospitalRecruiting
- Army Medical Center of PLARecruiting
- Hunan Cancer Hospital-Thoracic Medicine Department IRecruiting
- Hunan Cancer Hospital-Thoracic Medicine Department ⅡRecruiting
- Xiangya Hospital Central South University
- Shaoyang Central HospitalRecruiting
- Zhuzhou Central Hospital
- Affiliated Drum Tower Hospital, Medical School of Nanjing University
- Zhongda Hospital Southeast UniversityRecruiting
- Nantong Tumor Hospital
- Affiliated Hospital of JiangNan UniversityRecruiting
- The Affiliated Hospital of Xuzhou Medical University
- Northern Jiangsu People's HospitalRecruiting
- First Affiliated Hospital of Gannan Medical University
- The First Affiliated Hospital of Nanchang UniversityRecruiting
- The Second Affiliated Hospital of Nanchang UniversityRecruiting
- Liaoning Cancer Hospital
- Shengjing Hospital Affiliated to China Medical University
- The First Hospital of China Medical University
- Chifeng City Hospital
- The Affiliated Hospital of Inner Mongolia Medical University
- Qilu Hospital of Shandong University
- Shandong Cancer Hospital&Institute
- The Affiliated of Qingdao University
- LinYi Cancer Hospital
- Fudan University Shanghai Cancer Center
- Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
- Shanghai Chest Hospital
- Shanghai Pulmonary HospitalRecruiting
- Baoji Central Hospital
- Changzhi People's Hospital
- General Hospital of TISCO
- Shanxi Bethune Hospital
- Shanxi Provincial Cancer HospitalRecruiting
- The Second Affiliated Hospital of Air Force Military University Tangdu HospitalRecruiting
- Sichuan Cancer Hospital
- The Affiliated Hospital of Southwest Medical University
- Mianyang Central Hospital
- Yibin Second People's Hospital
- Tianjin Medical University Cancer Institute & HospitalRecruiting
- Yunnan Cancer Hospital
- Hangzhou Cancer Hospital
- The First Affiliated Hospital, College of Medicine, Zhejiang University of Medicine
- The Second Affiliated Hospital of Zhejiang University School of Medicine
- ZheJiang Cancer Hospital
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm Type
Experimental
Experimental
Experimental
Arm Label
camrelizumab + famitinib
pembrolizumab
camrelizumab
Arm Description
Outcomes
Primary Outcome Measures
PFS assessed by BIRC
Progression-Free-Survival, defined as the time from randomization to the first occurrence of disease progression as determined by IRC with use of RECIST v1.1 or death from any cause, whichever occurs first.
Secondary Outcome Measures
PFS assessed by investigator
Progression-Free-Survival
ORR
Objective Response Rate, determined using RECIST v1.1 criteria, defined as best overall response (CR or PR) across all assessment time points
DCR
Disease Control Rate, determined using RECIST v1.1 criteria
DoR
Duration of Response, determined using RECIST v1.1 criteria
TTF
Time to Treatment Failure, defined as the time from randomization to treatment discontinuation.
AEs+SAEs
Adverse Events and Serious Adverse Events
OS
OS is the time interval from the date of randomization to death due to any reason or lost of follow-up
Full Information
NCT ID
NCT05042375
First Posted
September 1, 2021
Last Updated
November 16, 2022
Sponsor
Jiangsu HengRui Medicine Co., Ltd.
1. Study Identification
Unique Protocol Identification Number
NCT05042375
Brief Title
A Trial of Camrelizumab Combined With Famitinib Malate in Treatment Naïve Subjects With PD-L1-Positive Recurrent or Metastatic Non-Small Cell Lung Cancer
Official Title
A Randomized, Open-Label, Controlled, Multi-center Phase Ⅲ Study of Camrelizumab Combined With Famitinib Malate Versus Pembrolizumab in Treatment Naïve Subjects With PD-L1-Positive Recurrent or Metastatic Non-Small Cell Lung Cancer
Study Type
Interventional
2. Study Status
Record Verification Date
October 2022
Overall Recruitment Status
Recruiting
Study Start Date
September 8, 2022 (Actual)
Primary Completion Date
December 31, 2023 (Anticipated)
Study Completion Date
December 31, 2025 (Anticipated)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Sponsor
Name of the Sponsor
Jiangsu HengRui Medicine Co., Ltd.
4. Oversight
Studies a U.S. FDA-regulated Drug Product
No
Studies a U.S. FDA-regulated Device Product
No
5. Study Description
Brief Summary
The study is being conducted to evaluate the efficacy, and safety of camrelizumab combined with famitinib malate vs. pembrolizumab in treatment naïve subjects with programmed death-ligand 1(PD-L1)-positive recurrent or metastatic non-small cell lung cancer (NSCLC).
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Non-small Cell Lung Cancer
7. Study Design
Primary Purpose
Treatment
Study Phase
Phase 3
Interventional Study Model
Parallel Assignment
Model Description
Camrelizumab Combined with Famitinib Malate versus Pembrolizumab
Masking
None (Open Label)
Allocation
Randomized
Enrollment
450 (Anticipated)
8. Arms, Groups, and Interventions
Arm Title
camrelizumab + famitinib
Arm Type
Experimental
Arm Title
pembrolizumab
Arm Type
Experimental
Arm Title
camrelizumab
Arm Type
Experimental
Intervention Type
Drug
Intervention Name(s)
camrelizumab + famitinib
Intervention Description
Camrelizumab for injection, 200 mg; Famitinib malate capsules, 20 mg.
Intervention Type
Drug
Intervention Name(s)
pembrolizumab
Intervention Description
pembrolizumab 200 mg.
Intervention Type
Drug
Intervention Name(s)
camrelizumab
Intervention Description
Camrelizumab for injection, 200 mg.
Primary Outcome Measure Information:
Title
PFS assessed by BIRC
Description
Progression-Free-Survival, defined as the time from randomization to the first occurrence of disease progression as determined by IRC with use of RECIST v1.1 or death from any cause, whichever occurs first.
Time Frame
up to 3 years
Secondary Outcome Measure Information:
Title
PFS assessed by investigator
Description
Progression-Free-Survival
Time Frame
up to 3 years
Title
ORR
Description
Objective Response Rate, determined using RECIST v1.1 criteria, defined as best overall response (CR or PR) across all assessment time points
Time Frame
up to 3 years
Title
DCR
Description
Disease Control Rate, determined using RECIST v1.1 criteria
Time Frame
up to 3 years
Title
DoR
Description
Duration of Response, determined using RECIST v1.1 criteria
Time Frame
up to 3 years
Title
TTF
Description
Time to Treatment Failure, defined as the time from randomization to treatment discontinuation.
Time Frame
up to 3 years
Title
AEs+SAEs
Description
Adverse Events and Serious Adverse Events
Time Frame
from the first drug administration to within 90 days for the last SHR-1210 dose
Title
OS
Description
OS is the time interval from the date of randomization to death due to any reason or lost of follow-up
Time Frame
up to 4 years
10. Eligibility
Sex
All
Minimum Age & Unit of Time
18 Years
Maximum Age & Unit of Time
75 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria:
Have a histologically or cytologically confirmed diagnosis of metastatic NSCLC (stage IV according to the TNM staging criteria [8th edition] published by the International Association for the Study of Lung Cancer [IASLC]), or NSCLC that recurs after curable surgery, radiotherapy, or radiochemotherapy.
Have measurable disease based on RECIST v1.1.
ECOG PS score: 0-1.
Have a life expectancy of at least 3 months.
Non-surgically sterilized female subjects or women of childbearing potential must be negative for a serum pregnancy test within 3 days prior to the first dose and must be non-lactating. Female subjects of childbearing potential and male subjects with partners of childbearing potential must agree to take highly effective contraceptive measures during the study period and within 6 months after the last dose of study drugs.
Have voluntarily agreed to participate by giving written informed consent for the study, have good compliance, and cooperate with follow-up visits.
Exclusion Criteria:
Accompanied with EGFR activating mutation, ALK fusion gene positive or ROS1 mutation.
Have uncontrolled clinically symptomatic pleural effusion, pericardial effusion, or ascites.
Have known history of prior malignancy in the past 3 years.
Have had an allogeneic tissue/solid organ transplant.
Have active pulmonary tuberculosis.
Have clinical symptoms of the heart or heart diseases that are not well controlled.
Have hypertension which cannot be well controlled by antihypertensives
Urinalysis has indicated that the urine protein is ≥ ++ and quantitative test of urine protein has confirmed that the 24-h urine protein is > 1.0 g.
Have a thrombosis tendency or are currently receiving thrombolysis/anticoagulation therapy.
Have received major surgery within 4 weeks prior to randomization; or palliative radiotherapy within 2 weeks prior to randomization; or have not recovered from the toxicities and/or complications of previous interventions to NCI-CTCAE Grade ≤ 1.
Have known history of arterial/venous thrombosis within 6 months prior to randomization, such as cerebrovascular accidents, deep vein thrombosis and pulmonary embolism.
Have received prior therapy with anti-PD-1/PD-L1 monoclonal antibodies, anti-CTLA-4 monoclonal antibodies, or small molecule VEGFR inhibitors.
Have known allergies to other monoclonal antibodies or any component of famitinib.
Are currently participating and receiving study therapy or have participated in a study and received the last dose of study drug within 4 weeks (or 5 half-lives of the study drug) prior to randomization.
Have other potential factors that may affect the study results or result in the premature discontinuation as determined by the investigator, such as alcoholism, drug abuse, substance abuse, other serious diseases (including mental illness) requiring concomitant treatment, serious laboratory abnormalities, or family or social factors that could affect the safety of medication.
Central Contact Person:
First Name & Middle Initial & Last Name or Official Title & Degree
weixia Li, M.M
Phone
+86-15005136260
Email
Weixia.li@hengrui.com
Facility Information:
Facility Name
The First Affiliated Hospital of Bengbu Medical College
City
Bengbu
State/Province
Anhui
ZIP/Postal Code
233000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Chengling Zhao
Facility Name
Anhui Chest Hospital
City
Hefei
State/Province
Anhui
ZIP/Postal Code
230000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Haowei Fang
Facility Name
Anhui Provincial Cancer Hospital
City
Hefei
State/Province
Anhui
ZIP/Postal Code
230000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Zhihong Zhang
Facility Name
Anhui Provincial Hospital
City
Hefei
State/Province
Anhui
ZIP/Postal Code
230000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Xinghua Han
Facility Name
The First Affiliated Hospital Of Anhui Medical University
City
Hefei
State/Province
Anhui
ZIP/Postal Code
230000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yingying Du
Facility Name
Beijing Cancer Hospital
City
Beijing
State/Province
Beijing
ZIP/Postal Code
100000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jian Fang
Facility Name
Beijing Chest Hospital,Capital Medical University
City
Beijing
State/Province
Beijing
ZIP/Postal Code
100000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Tongmei Zhang
Facility Name
Peking University Third Hospital
City
Beijing
State/Province
Beijing
ZIP/Postal Code
100000
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Baoshan Cao
Facility Name
ChongQing University Cancer Hospital
City
Chongqing
State/Province
Chongqing
ZIP/Postal Code
400000
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Luchun LI
Facility Name
Fujian Medical University Union Hospital
City
Fuzhou
State/Province
Fujian
ZIP/Postal Code
350000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jinhuo Lai
Facility Name
Fujian Provincial Cancer Hospital
City
Fuzhou
State/Province
Fujian
ZIP/Postal Code
350000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Zhiyong He
Facility Name
The First Affiliated Hospital of Xiamen University
City
Xiamen
State/Province
Fujian
ZIP/Postal Code
361000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Qihong Zhuang
Facility Name
The Second Affiliated Hospital of Xiamen Medical College
City
Xiamen
State/Province
Fujian
ZIP/Postal Code
361000
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Hui Yang
Facility Name
The People's Hospital of Gaozhou
City
Gaozhou
State/Province
Guangdong
ZIP/Postal Code
525200
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Wanli Lin
Facility Name
Affiliated Cancer Hospital and Institute of Guangzhou Medical University
City
Guangzhou
State/Province
Guangdong
ZIP/Postal Code
510000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jian Wang
Facility Name
The First Affiliated Hospital of Guangzhou Medical University
City
Guangzhou
State/Province
Guangdong
ZIP/Postal Code
510000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Chengzhi Zhou
Facility Name
The First Affiliated Hospital of Guangzhou University of Chinese Medicine
City
Guangzhou
State/Province
Guangdong
ZIP/Postal Code
510000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Lizhu Lin
Facility Name
Meizhou People's Hospital (Huangtang Hospital)
City
Meizhou
State/Province
Guangdong
ZIP/Postal Code
514000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Guowu Wu
Facility Name
Shantou Central Hospital
City
Shantou
State/Province
Guangdong
ZIP/Postal Code
515000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Xunyan Liu
Facility Name
Affiliated Hospital of Guangdong Medical University
City
Zhanjiang
State/Province
Guangdong
ZIP/Postal Code
524000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Hualin Chen
Facility Name
Affiliated Hospital of Guilin Medical University
City
Guilin
State/Province
Guangxi
ZIP/Postal Code
541000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Mafei Kang
Facility Name
Guangxi Medical University Affiliated Tumor Hospital
City
Nanning
State/Province
Guangxi
ZIP/Postal Code
530000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Aiping Zeng
Facility Name
The First Affiliated Hospital of Guangxi Medical University
City
Nanning
State/Province
Guangxi
ZIP/Postal Code
530000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Zhiyi He
Facility Name
Affiliated Hospital of Zunyi Medical University
City
Zunyi
State/Province
Guizhou
ZIP/Postal Code
563000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Liang Zhou
Facility Name
Hainan General Hospital
City
Haikou
State/Province
Hainan
ZIP/Postal Code
570100
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yongxing Chen
Facility Name
The Fourth Hospital of Hebei Medical University
City
Shijiazhuang
State/Province
Hebei
ZIP/Postal Code
050000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jun Wang
Facility Name
North China University Of Science And Technology Affiliated Hospital
City
Tangshan
State/Province
Hebei
ZIP/Postal Code
063000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Guogui Sun
Facility Name
Xingtai People's Hospital
City
Xingtai
State/Province
Hebei
ZIP/Postal Code
054000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yonghui Di
Facility Name
Haerbin Medical University Cancer Hospital
City
Ha'erbin
State/Province
Heilongjiang
ZIP/Postal Code
150000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yan Wang
Facility Name
Anyang Cancer Hospital
City
Anyang
State/Province
Henan
ZIP/Postal Code
455000
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yonggui Hong
Facility Name
The First Affiliated Hosptial of Henan University of Science & Technology
City
Luoyang
State/Province
Henan
ZIP/Postal Code
471000
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jun Yao
Facility Name
Henan Cancer Hospital
City
Zhengzhou
State/Province
Henan
ZIP/Postal Code
450000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Qiming Wang
Facility Name
The First Affiliated Hospital of Zhengzhou University
City
Zhengzhou
State/Province
Henan
ZIP/Postal Code
450000
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Guojun Zhang
Facility Name
Shiyan Taihe Hospital
City
Shiyan
State/Province
Hubei
ZIP/Postal Code
442000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Meifang Wang
Facility Name
Union Hospital Tongji Medical College Huazhong University of Science and Technology
City
Wuhan
State/Province
Hubei
ZIP/Postal Code
430000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Xiaorong Dong
Facility Name
Xiangyang Central Hospital
City
Xiangyang
State/Province
Hubei
ZIP/Postal Code
441000
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Tienan Yi
Facility Name
Army Medical Center of PLA
City
Changsha
State/Province
Hunan
ZIP/Postal Code
410000
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Xuewen Liu
Facility Name
Hunan Cancer Hospital-Thoracic Medicine Department I
City
Changsha
State/Province
Hunan
ZIP/Postal Code
410000
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yongzhong Luo
Facility Name
Hunan Cancer Hospital-Thoracic Medicine Department Ⅱ
City
Changsha
State/Province
Hunan
ZIP/Postal Code
410000
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Lin Wu
Facility Name
Xiangya Hospital Central South University
City
Changsha
State/Province
Hunan
ZIP/Postal Code
410000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Huaping Yang
Facility Name
Shaoyang Central Hospital
City
Shaoyang
State/Province
Hunan
ZIP/Postal Code
422000
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Xinfu Liu
Facility Name
Zhuzhou Central Hospital
City
Zhuzhou
State/Province
Hunan
ZIP/Postal Code
412000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Bo Qiu
Facility Name
Affiliated Drum Tower Hospital, Medical School of Nanjing University
City
Nanjing
State/Province
Jiangsu
ZIP/Postal Code
210000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yongsheng Wang
Facility Name
Zhongda Hospital Southeast University
City
Nanjing
State/Province
Jiangsu
ZIP/Postal Code
210000
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Ruifeng Zhang
Facility Name
Nantong Tumor Hospital
City
Nantong
State/Province
Jiangsu
ZIP/Postal Code
226000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Junguo Lu
Facility Name
Affiliated Hospital of JiangNan University
City
Wuxi
State/Province
Jiangsu
ZIP/Postal Code
214000
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Xiaoping Chen
Facility Name
The Affiliated Hospital of Xuzhou Medical University
City
Xuzhou
State/Province
Jiangsu
ZIP/Postal Code
221000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Bi Chen
Facility Name
Northern Jiangsu People's Hospital
City
Yangzhou
State/Province
Jiangsu
ZIP/Postal Code
225000
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Xingxiang Xu
Facility Name
First Affiliated Hospital of Gannan Medical University
City
Ganzhou
State/Province
Jiangxi
ZIP/Postal Code
341000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Huaqiu Shi
Facility Name
The First Affiliated Hospital of Nanchang University
City
Nanchang
State/Province
Jiangxi
ZIP/Postal Code
330000
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Fei Xu
Facility Name
The Second Affiliated Hospital of Nanchang University
City
Nanchang
State/Province
Jiangxi
ZIP/Postal Code
330000
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Anwen Liu
Facility Name
Liaoning Cancer Hospital
City
Shenyang
State/Province
Liaoning
ZIP/Postal Code
110000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jinghui Bai
Facility Name
Shengjing Hospital Affiliated to China Medical University
City
Shenyang
State/Province
Liaoning
ZIP/Postal Code
110000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Wei Zheng
Facility Name
The First Hospital of China Medical University
City
Shenyang
State/Province
Liaoning
ZIP/Postal Code
110000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Bo Jin
Facility Name
Chifeng City Hospital
City
Chifeng
State/Province
Neimenggu
ZIP/Postal Code
024000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Minghui Zhang
Facility Name
The Affiliated Hospital of Inner Mongolia Medical University
City
Hohhot
State/Province
Neimenggu
ZIP/Postal Code
010000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Qun Hu
Facility Name
Qilu Hospital of Shandong University
City
Jinan
State/Province
Shandong
ZIP/Postal Code
250000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yufeng Cheng
Facility Name
Shandong Cancer Hospital&Institute
City
Jinan
State/Province
Shandong
ZIP/Postal Code
250000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Xiqin Zhang
Facility Name
The Affiliated of Qingdao University
City
Qingdao
State/Province
Shandong
ZIP/Postal Code
266000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jing Wang
Facility Name
LinYi Cancer Hospital
City
Linyi
State/Province
Shangdong
ZIP/Postal Code
276000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jianhua Shi
Facility Name
Fudan University Shanghai Cancer Center
City
Shanghai
State/Province
Shanghai
ZIP/Postal Code
200000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Si Sun
Facility Name
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
City
Shanghai
State/Province
Shanghai
ZIP/Postal Code
200000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Min Zhou
Facility Name
Shanghai Chest Hospital
City
Shanghai
State/Province
Shanghai
ZIP/Postal Code
200000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Hua Zhong
Facility Name
Shanghai Pulmonary Hospital
City
Shanghai
State/Province
Shanghai
ZIP/Postal Code
200000
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Caicun Zhou
Facility Name
Baoji Central Hospital
City
Baoji
State/Province
Shanxi
ZIP/Postal Code
721000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yaning Zhao
Facility Name
Changzhi People's Hospital
City
Changzhi
State/Province
Shanxi
ZIP/Postal Code
046000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jun Zhao
Facility Name
General Hospital of TISCO
City
Taiyuan
State/Province
Shanxi
ZIP/Postal Code
030000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Weihua Jia
Facility Name
Shanxi Bethune Hospital
City
Taiyuan
State/Province
Shanxi
ZIP/Postal Code
030000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Qi Mei
Facility Name
Shanxi Provincial Cancer Hospital
City
Taiyuan
State/Province
Shanxi
ZIP/Postal Code
030000
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Weihua Yang
Facility Name
The Second Affiliated Hospital of Air Force Military University Tangdu Hospital
City
Xi'an
State/Province
Shanxi
ZIP/Postal Code
710000
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Haichuan Su
Facility Name
Sichuan Cancer Hospital
City
Chengdu
State/Province
Sichuan
ZIP/Postal Code
610000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Wenxiu Yao
Facility Name
The Affiliated Hospital of Southwest Medical University
City
Luzhou
State/Province
Sichuan
ZIP/Postal Code
646000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Peirong Ren
Facility Name
Mianyang Central Hospital
City
Mianyang
State/Province
Sichuan
ZIP/Postal Code
621000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Weiguo Xu
Facility Name
Yibin Second People's Hospital
City
Yibin
State/Province
Sichuan
ZIP/Postal Code
644000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Shanbing Wang
Facility Name
Tianjin Medical University Cancer Institute & Hospital
City
Tianjin
State/Province
Tianjin
ZIP/Postal Code
300000
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Dingzhi Huang
Facility Name
Yunnan Cancer Hospital
City
Kunming
State/Province
Yunnan
ZIP/Postal Code
650000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yunchao Huang
Facility Name
Hangzhou Cancer Hospital
City
Hangzhou
State/Province
Zhejiang
ZIP/Postal Code
310000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Xueqin Chen
Facility Name
The First Affiliated Hospital, College of Medicine, Zhejiang University of Medicine
City
Hangzhou
State/Province
Zhejiang
ZIP/Postal Code
310000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jianya Zhou
Facility Name
The Second Affiliated Hospital of Zhejiang University School of Medicine
City
Hangzhou
State/Province
Zhejiang
ZIP/Postal Code
310000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Wen Li
Facility Name
ZheJiang Cancer Hospital
City
Hangzhou
State/Province
Zhejiang
ZIP/Postal Code
310000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yun Fan
12. IPD Sharing Statement
Plan to Share IPD
Undecided
Learn more about this trial
A Trial of Camrelizumab Combined With Famitinib Malate in Treatment Naïve Subjects With PD-L1-Positive Recurrent or Metastatic Non-Small Cell Lung Cancer
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