Accurate Screening Tools for Dysphagia in Amyotrophic Lateral Sclerosis (ALS)
Amyotrophic Lateral Sclerosis
About this trial
This is an interventional diagnostic trial for Amyotrophic Lateral Sclerosis
Eligibility Criteria
Inclusion Criteria:
- diagnosis of probable or definite ALS
Exclusion Criteria:
- allergies to barium or capsaicin
- tracheotomy or mechanical ventilation
- absence of diaphragmatic pacer
- respiratory disease (COPD).
Sites / Locations
- University of Florida
Arms of the Study
Arm 1
Experimental
Screening
Participants enrolled will have the following test: Micro Mouth Pressure Meter, reflexive cough testing (with capsaicin used in blocks), lingual strength and endurance trials using the Iowa Oral Performance Instrument, Electrical Impedance Myography of the tongue, Pulmonary Function Testing, and a Videofluoroscopic Swallowing Study. In addition, the patient will complete the following surveys: Swallowing Related Quality of Life Questionnaire (SWAL-QOL), Eating Assessment Tool-10 (EAT-10), Functional Oral Intake Scale (FOIS), Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised (ALSFRS-R), The Center for Neurologic Studies Bulbar Function Scale (CNS-BFS), and the Communicative Effectiveness Survey (CES).