Addition of FFRct in the Diagnostic Pathway of Patients With Stable Chest Pain (Fusion)
Chest Pain, Epicardial Plaques
About this trial
This is an interventional diagnostic trial for Chest Pain focused on measuring Stable chest pain, Coronary Angiography, major epicardial vessel stenosis
Eligibility Criteria
Inclusion Criteria:
- Age ≥ 18 years
- Stable chest pain and the patient underwent CCTA which demonstrated ≥50% but less than 90% stenosis in any major epicardial vessel with a diameter ≥ 2 mm.
Exclusion Criteria:
- Inability to provide informed consent
- Unstable angina according to ESC guidelines
- Unstable clinical status
- Expected inability to complete follow-up and comply with follow-up aspects of the protocol
- History of coronary revascularisation
- Non-invasive or invasive diagnostic testing for CAD within the past 12 months (with the exception of exercise ECG)
- Unsuitable for revascularisation if required (for example due to comorbidities or anatomical features)
- Poor CT quality with expected inability to perform FFRct analysis
Sites / Locations
- ErasmusmcRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
No Intervention
The intervention group (FFRct group)
Standard treatment not using result of FFRct analyses
The people in this group receive an FFRct analysis, which will be included in the treatment plan. If the FFRct analysis shows that there are there is no significant narrowing in your case, then in principle no invasive examination (heart catheterization) performed. If the analysis indicates a significant narrowing, then an invasive cardiac catheterization will usually be required are carried out. The final treatment plan will always be reviewed by your doctor tailored to your individual situation
The people in this group receive the regular treatment. This is usually an invasive cardiac catheterization. The additional FFRct analysis is also included in this group, but it is not included in the treatment plan.