Adductor Canal Versus Femoral Nerve Block for Analgesia Post Total Knee Arthroscopy
Primary Purpose
Knee Osteoarthritis
Status
Unknown status
Phase
Not Applicable
Locations
Singapore
Study Type
Interventional
Intervention
Ropivacaine
Sponsored by
About this trial
This is an interventional treatment trial for Knee Osteoarthritis focused on measuring Total knee arthroplasty, Total knee replacement, Femoral Nerve Block, Adductor Canal Block
Eligibility Criteria
Inclusion Criteria:
- ages 45-85
- American Society of Anaesthesiologists physical status 1-3
- BMI 18-35 kg/m2
Exclusion Criteria:
- inability to give consent, communicate, cooperate
- Patients with regular consumption of strong opioids (morphine, oxycodone) or steroids
- Patients with allergy to local anaesthetics or any drugs included in the study
- Patients with lower limb surgery in the preceding year
- Patients with pre-existing neurological deficits
- Patients who are unsuitable for general anaesthetics (eg difficult airway)
Sites / Locations
- Changi General HospitalRecruiting
Arms of the Study
Arm 1
Arm 2
Arm Type
Active Comparator
Active Comparator
Arm Label
Femoral Nerve Block
Adductor Canal block
Arm Description
Femoral Nerve block performed with 0.5% Ropivacaine 30mls (150mg)
Adductor Canal block performed with 0.5% Ropivacaine 30mls (150mg)
Outcomes
Primary Outcome Measures
Morphine consumption
Secondary Outcome Measures
Pain scores
Morphine consumption
Side effects of opioids- sedation, nausea and vomiting
Quadriceps strength, ability to mobilise
Full Information
NCT ID
NCT02033603
First Posted
January 9, 2014
Last Updated
December 31, 2014
Sponsor
Changi General Hospital
1. Study Identification
Unique Protocol Identification Number
NCT02033603
Brief Title
Adductor Canal Versus Femoral Nerve Block for Analgesia Post Total Knee Arthroscopy
Official Title
A Randomised Controlled Trial Comparing Single Shot Adductor Canal Block With Femoral Nerve Block for Analgesia Post Total Knee Arthroplasty
Study Type
Interventional
2. Study Status
Record Verification Date
January 2014
Overall Recruitment Status
Unknown status
Study Start Date
January 2014 (undefined)
Primary Completion Date
September 2014 (Actual)
Study Completion Date
December 2014 (Anticipated)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Sponsor
Name of the Sponsor
Changi General Hospital
4. Oversight
Data Monitoring Committee
No
5. Study Description
Brief Summary
Total knee arthroplasty or replacement (TKA) is a surgery performed for osteoarthritis of the knee which is increasingly performed as the population ages. It is a painful surgery and one of the methods to reduce post-operative pain is performing a regional anaesthesia technique. The current practice is to perform a femoral nerve block (FNB) which blocks the nerves supplying the knee joint and the thigh muscles (quadriceps). This provides effective analgesia. However, it also results in weakness of the quadriceps and may result in falls post-operatively.
Adductor canal block (ACB) is a new, alternative regional anaesthesia technique which is hypothesised to provide as effective analgesia, with less quadriceps weakness compared to FNB, hence potentially reducing the risk of falls post-operatively.
Investigators aim to study if the analgesia provided by ACB is as good as FNB while preserving quadriceps strength.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Knee Osteoarthritis
Keywords
Total knee arthroplasty, Total knee replacement, Femoral Nerve Block, Adductor Canal Block
7. Study Design
Primary Purpose
Treatment
Study Phase
Not Applicable
Interventional Study Model
Parallel Assignment
Masking
ParticipantOutcomes Assessor
Allocation
Randomized
Enrollment
30 (Anticipated)
8. Arms, Groups, and Interventions
Arm Title
Femoral Nerve Block
Arm Type
Active Comparator
Arm Description
Femoral Nerve block performed with 0.5% Ropivacaine 30mls (150mg)
Arm Title
Adductor Canal block
Arm Type
Active Comparator
Arm Description
Adductor Canal block performed with 0.5% Ropivacaine 30mls (150mg)
Intervention Type
Drug
Intervention Name(s)
Ropivacaine
Other Intervention Name(s)
naropin
Intervention Description
30mls of 0.5% ropivacaine
Primary Outcome Measure Information:
Title
Morphine consumption
Time Frame
first 24 hours
Secondary Outcome Measure Information:
Title
Pain scores
Time Frame
1, 6, 12, 24, 48
Title
Morphine consumption
Time Frame
48 hours
Title
Side effects of opioids- sedation, nausea and vomiting
Time Frame
48 hours
Title
Quadriceps strength, ability to mobilise
Time Frame
24, 48 hours
10. Eligibility
Sex
All
Minimum Age & Unit of Time
45 Years
Maximum Age & Unit of Time
85 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria:
ages 45-85
American Society of Anaesthesiologists physical status 1-3
BMI 18-35 kg/m2
Exclusion Criteria:
inability to give consent, communicate, cooperate
Patients with regular consumption of strong opioids (morphine, oxycodone) or steroids
Patients with allergy to local anaesthetics or any drugs included in the study
Patients with lower limb surgery in the preceding year
Patients with pre-existing neurological deficits
Patients who are unsuitable for general anaesthetics (eg difficult airway)
Central Contact Person:
First Name & Middle Initial & Last Name or Official Title & Degree
CTRU CGH
Phone
67888833
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Yean Chin Lim, MBBS, MMed
Organizational Affiliation
Changi General Hospital
Official's Role
Principal Investigator
Facility Information:
Facility Name
Changi General Hospital
City
Singapore
ZIP/Postal Code
529889
Country
Singapore
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
CTRU
Phone
67888833
12. IPD Sharing Statement
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Adductor Canal Versus Femoral Nerve Block for Analgesia Post Total Knee Arthroscopy
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