Aerobic Exercise Intervention for Knee Osteoarthritis
Osteoarthritis
About this trial
This is an interventional treatment trial for Osteoarthritis focused on measuring knee, aerobic exercise, walking, cycling, gait, MRI
Eligibility Criteria
Inclusion Criteria Current symptoms of chronic (6 months), stable pain and/or stiffness in one or both knees during weight-bearing activities Involved joint is primary factor limiting physical or functional activity Radiographic signs of mild or moderate arthritis Mild joint space narrowing (at least 2mm remaining) Exclusion Criteria Current participation in a regular exercise program Existing medical condition that would preclude increased physical activity Subjective complaint of instability (giving way) Ligamentous instability greater than Grade I Knee flexion contracture greater than 15 degrees Asymptomatic osteoarthritis of both knees, incapacitating arthritis, or inflammatory arthritis Major reconstructive surgery on a lower extremity joint Multiple major joint involvement Any condition which severely limits local ambulation, such as amputation or stroke Gait aids used majority of time for ambulation Cannot use step-over-step techniques in either ascending or descending stair conditions Not able to undergo MRI scan (e.g., cardiac pacemaker) Dementia or inability to give informed consent as determined by a Folstein Mini Mental score greater than 24
Sites / Locations
- Mayo Clinic
Arms of the Study
Arm 1
Arm 2
Arm 3
No Intervention
Experimental
Experimental
1
2
3
Participants will receive no intervention and will act as the control group.
Participants will partake in a walking exercise program.
Participants will partake in a cycling exercise program.