Alveolar Ridge Preservation With Putty Allograft vs. Putty Alloplast Graft
Alveolar Bone Resorption
About this trial
This is an interventional treatment trial for Alveolar Bone Resorption focused on measuring Alveolar ridge preservation, Socket preservation
Eligibility Criteria
Inclusion Criteria:
Have one non-molar tooth requiring extraction that will be replaced by a dental implant.
The site must be bordered by at least one tooth.
- Healthy male or female who is at least 18 years old.
- Patients must sign an informed consent approved by the University of Louisville Human Studies Committee.
Exclusion Criteria:
- Patients with debilitating systemic diseases, or diseases that have a clinically significant effect on the periodontium.
- Presence or history of osteonecrosis of jaws.
- Patients who are currently taking IV bisphosphonates or who had IV treatment with bisphosphonates irrespective of duration.
- Patients who have been treated with oral bisphosphonates for more than three years.
- Patients with an allergy to any material or medication used in the study.
- Patients who need prophylactic antibiotics
- Previous head and neck radiation therapy.
- Chemotherapy in the previous 12 months.
- Patients on long term NSAID or steroid therapy.
- Pregnant patients.
Sites / Locations
- University of LouisvilleRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
demineralized and mineralized combination putty bone allograft
calcium phosphosilicate putty alloplast graft
Fifteen test patients will receive an intrasocket demineralized and mineralized combination putty allograft (MinerOss Putty, BioHorizons) with a regenerative tissue matrix membrane (AlloDerm GBR, BioHorizons) following tooth extraction.
The positive control group of fifteen patients will receive an intrasocket synthetic resorbable calcium phosphosilicate putty alloplast graft (NovaBone, Osteogenics) covered with a regenerative tissue matrix membrane (AlloDerm GBR, BioHorizons) following tooth extraction.