An Efficacy and Safety Study of Galantamine for the Treatment of Patients With Alzheimer's Disease.
Alzheimer Disease
About this trial
This is an interventional treatment trial for Alzheimer Disease focused on measuring Alzheimer's disease, Cognitive dysfunction
Eligibility Criteria
Inclusion Criteria: Outpatients with a diagnosis of Alzheimer's disease according to the National Institute of Neurological and Communicative Disorders and the Alzheimer's Disease and Related Disorders Association (NINCDS-ADRDA) criteria having a Mini-Mental Status Examination (MMSE) score of 10 - 22 inclusive having an Alzheimer's Disease Assessment Scale - Japan cognitive subscale (ADAS-J cog) score of at least 18 exhibiting an onset and progression of cognitive dysfunction during at least 6 months prior to the screening period Exclusion Criteria: Patients with neurodegenerative diseases other than Alzheimer's disease, such as Lewy bodies disease, (dementia due to tiny round structures made of proteins that develop within nerve cells in the brain), Parkinsonism, etc Patients with cognitive dysfunction due to cerebral damage resulting from a lack of oxygen, a brain injury, etc Patients with multi-infarct dementia (brought on by a series of strokes) or active cerebrovascular disease Patients with clinically significant cardiovascular disease Patients currently taking drugs such as a cholinesterase inhibitors, which improve cerebral circulation/metabolism