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Anemia Treatment for Advanced Non-Small Cell Lung Cancer (NSCLC) Patients Receiving Chemotherapy

Primary Purpose

Non-Small Cell Lung Cancer, Anemia, Cancer

Status

Terminated

Phase

Phase 3

Locations

International

Study Type

Interventional

Intervention

Darbepoetin alfa

Placebo

About this trial

This is an interventional supportive care trial for Non-Small Cell Lung Cancer focused on measuring darbepoetin alfa, non-small cell lung cancer, Aranesp, chemotherapy, chemotherapy induce anemia, advanced lung cancer, malignant pleural effusion, metastatic lung cancer, NSCLC, anemia, lung cancer, pleural effusion, Stage IIIB lung cancer, Stage IV lung cancer

Eligibility Criteria

18 Years - undefined (Adult, Older Adult)All SexesDoes not accept healthy volunteers

Inclusion Criteria:

Subjects with stage IV NSCLC (not recurrent or re-staged).
Expected to receive at least 2 additional cycles (at least 6 total weeks) of first line myelosuppressive cyclic chemotherapy after randomization. Subjects should not be expected to receive only maintenance chemotherapy.
Eastern Cooperative Oncology Group performance status of 0 or 1 as assessed within 21 days prior to randomization.
18 years of age or older at screening.
Life expectancy greater than 6 months based on the judgment of the investigator and documented during screening.
Hemoglobin level less than or equal to 11.0 g/dL as assessed by the local laboratory; sample obtained within 7 days prior to randomization (retest in screening is acceptable).
Adequate serum folate (greater than or equal to 2 ng/mL) and vitamin B12 (greater than or equal to 200 pg/mL) levels assessed by central laboratory (supplementation and retest acceptable) during screening.
Subjects must have had a baseline scan (computed tomography [CT], magnetic resonance imaging [MRI], or positron emission tomography-computer tomography [PET/CT]) of the chest to assess disease burden before starting on first line chemotherapy for NSCLC and those images must have been reviewed by the investigator prior to randomization. If the scan was performed more than 28 days prior to randomization, an additional scan must be performed and reviewed by the investigator to confirm that the patient has not progressed before randomization.
Before any study-specific procedure, the appropriate written informed consent must be obtained from the subject or a legally accepted representative.

Exclusion Criteria:

Known primary benign or malignant hematologic disorder which can cause anemia.
History of, or current active cancer other than NSCLC, with the exception of curatively resected non-melanomatous skin cancer, curatively treated cervical carcinoma in situ, or other primary solid tumors curatively treated with no known active disease present and no curative treatment administered for the last 3 years.
Received any prior adjuvant or neoadjuvant therapy for NSCLC.
Subjects with a history of brain metastasis.
Uncontrolled hypertension (systolic blood pressure [BP] > 160 mmHg or diastolic BP > 100 mmHg), or as determined by the investigator during screening.
History of neutralizing antibody activity to recombinant human erythropoietin (rHuEPO) or darbepoetin alfa.
Uncontrolled angina, uncontrolled heart failure, or uncontrolled cardiac arrhythmia as determined by the investigator at screening. Subjects with known myocardial infarction within 6 months prior to randomization.
Subjects with a history of seizure disorder taking anti-seizure medication within 30 days prior to randomization.
Clinically significant systemic infection or uncontrolled chronic inflammatory disease (eg, rheumatoid arthritis, inflammatory bowel disease) as determined by the investigator during screening.
Known seropositivity for human immunodeficiency virus (HIV) or diagnosis of acquired immunodeficiency syndrome (AIDS), positive for hepatitis B surface antigen, or seropositive for hepatitis C virus
History of pure red cell aplasia
History of deep venous thrombosis or embolic event (eg, pulmonary embolism) within 6 months prior to randomization.
Transferrin saturation < 20% and ferritin < 50 ng/mL as assessed by the central laboratory during screening. Subjects must have both to be excluded (supplementation and retest acceptable).
Abnormal renal function (serum creatinine level > 2X upper limit of normal [ULN]) as assessed by the central laboratory during screening.
Abnormal liver function (total bilirubin > 2X ULN or liver enzymes alanine aminotransferase [ALT] or aspartate aminotransferase [AST] > 2.5X ULN for subjects without liver metastasis or ≥ 5X ULN for subjects with liver metastasis) as assessed by the central laboratory during screening. Subjects with documented Gilbert's Disease may be eligible.
Received any red blood cell (RBC) transfusion within 28 days prior to randomization.
Plan to receive any RBC transfusion between randomization and study day 1.
Known previous treatment failure to erythropoiesis stimulating agents (ESAs) (eg, rHuEPO, darbepoetin alfa).
ESA therapy within the 28 days prior to randomization.
Known hypersensitivity to recombinant ESAs or the excipients contained within the investigational product.
Less than 30 days since receipt of any investigational product or device. Investigational use/receipt of a medicinal product or device that has been approved by the country's local regulatory authority for any indication is permitted.
Subjects of reproductive potential who are pregnant, breast feeding or not willing to use effective contraceptive precautions during the study and for at least one month after the last dose of investigational product in the judgment of the investigator (including females of childbearing potential who are partners of male subjects).
Previously randomized to this study.
Investigator has concerns regarding the ability of the subject to give written informed consent and/or to comply with study procedures (including availability for follow up visits).

Arms of the Study

Arm 1

Arm 2

Arm Type

Placebo Comparator

Experimental

Arm Label

Placebo

Darbepoetin alfa

Arm Description

Participants received placebo once every 3 weeks (Q3W) administered subcutaneously until 3 weeks after the completion of chemotherapy or upon determination of disease progression, whichever occurred first.

Participants received darbepoetin alfa 500 µg once every 3 weeks (Q3W) administered subcutaneously until 3 weeks after the completion of chemotherapy or upon determination of disease progression, whichever occurred first.

Outcomes

Primary Outcome Measures

Overall Survival (OS)

Overall survival (OS) was defined as the time from randomization to the date of death due to any cause. Participants were censored on the date of last contact (ie, the date the participant was last known to be alive) if they were not known to have died.

Secondary Outcome Measures

Progression-free Survival (PFS)

Progression-free survival was defined as the time from randomization to the date of radiographic disease progression or death from any cause, whichever event occurred first. Participants without either event were censored on the date of their last disease assessment. Disease progression was based on the investigator's assessment of scans using the Response Evaluation Criteria in Solid Tumors (RECIST) version 1.0 or 1.1 depending on the timing of enrollment.

Percentage of Participants With a Red Blood Cell Transfusion or Hemoglobin ≤ 8.0 g/dL From Week 5 to End of the Efficacy Treatment Period

Any red blood cell (RBC) transfusion (packed RBCs or whole blood) given or a hemoglobin ≤ 8.0 g/dL on or after study day 29 until the EOETP, inclusive.

Number of Participants With Adverse Events of Special Interest

Adverse events of interest for darbepoetin alfa, based on clinical data in anemic patients with cancer to date, included the following categories: antibody-mediated pure red cell aplasia (PRCA), cardiac failure, central nervous system vascular disorders, convulsions, embolic and thrombotic events, hypersensitivity, hypertension, ischemic heart disease, malignancies, and severe cutaneous adverse reactions. Lack of efficacy and medication errors were also evaluated.

Percentage of Participants With an Objective Tumor Response

Objective response was defined as the incidence of a complete or partial response at any time during the study. Response was determined by the investigator's assessment of the scans using RECIST version 1.0 or 1.1 depending on the timing of enrollment.

Number of Participants Who Developed Neutralizing Antibodies to Darbepoetin Alfa

Developing antibody incidence was defined as neutralizing antibody positive postbaseline with a negative or no result at baseline.

Percentage of Participants With a Red Blood Cell Transfusion or Hemoglobin ≤ 8.0 g/dL From Week 1 to End of the Efficacy Treatment Period

Any red blood cell (RBC) transfusion (packed RBCs or whole blood) given or a hemoglobin ≤ 8.0 g/dL on or after study day 1 until the EOETP, inclusive.

Change From Baseline in Hemoglobin to End of Efficacy Treatment Period

Post-baseline hemoglobin values within 28 days after a RBC transfusion were not be used in the calculation of change.

Full Information

NCT ID

NCT00858364

First Posted

March 5, 2009

Last Updated

November 4, 2022

Sponsor

Amgen

1. Study Identification

Unique Protocol Identification Number

NCT00858364

Brief Title

Anemia Treatment for Advanced Non-Small Cell Lung Cancer (NSCLC) Patients Receiving Chemotherapy

Official Title

A Randomized, Double-blind, Placebo-controlled Study to Evaluate the Long-term Safety and Efficacy of Darbepoetin Alfa Administered at 500 µg Once-Every-3-Weeks in Anemic Subjects With Advanced Stage Non-small Cell Lung Cancer Receiving Multi-cycle Chemotherapy

Study Type

Interventional

2. Study Status

Record Verification Date

November 2022

Overall Recruitment Status

Terminated

Study Start Date

July 17, 2009 (Actual)

Primary Completion Date

June 7, 2017 (Actual)

Study Completion Date

June 7, 2017 (Actual)

3. Sponsor/Collaborators

Responsible Party, by Official Title

Sponsor

Name of the Sponsor

Amgen

4. Oversight

Data Monitoring Committee

Yes

5. Study Description

Brief Summary

This is a study in patients with chemotherapy induced anemia receiving multi-cycle chemotherapy for the treatment of stage IV non-small cell lung cancer (NSCLC). The primary objective of the study is to demonstrate that overall survival (OS) is not worse in participants on darbepoetin alfa treated to a hemoglobin ceiling of 12.0 g/dL compared to participants treated with placebo.

Detailed Description

Oversight Authorities continued: Colombia

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study

Non-Small Cell Lung Cancer, Anemia, Cancer, Lung Cancer

Keywords

darbepoetin alfa, non-small cell lung cancer, Aranesp, chemotherapy, chemotherapy induce anemia, advanced lung cancer, malignant pleural effusion, metastatic lung cancer, NSCLC, anemia, lung cancer, pleural effusion, Stage IIIB lung cancer, Stage IV lung cancer

7. Study Design

Primary Purpose

Supportive Care

Study Phase

Phase 3

Interventional Study Model

Parallel Assignment

Masking

ParticipantCare ProviderInvestigatorOutcomes Assessor

Allocation

Randomized

Enrollment

2549 (Actual)

8. Arms, Groups, and Interventions

Arm Title

Placebo

Arm Type

Placebo Comparator

Arm Description

Arm Title

Darbepoetin alfa

Arm Type

Experimental

Arm Description

Intervention Type

Drug

Intervention Name(s)

Darbepoetin alfa

Other Intervention Name(s)

Aranesp®

Intervention Description

Administered subcutaneously once every 3 weeks

Intervention Type

Drug

Intervention Name(s)

Placebo

Intervention Description

Administered subcutaneously once every 3 weeks

Primary Outcome Measure Information:

Title

Overall Survival (OS)

Description

Time Frame

From randomization until death or end of study; maximum time on follow-up was 93.6 months.

Secondary Outcome Measure Information:

Title

Progression-free Survival (PFS)

Description

Time Frame

From randomization until disease progression or death; maximum time on follow-up was 87.23 months.

Title

Percentage of Participants With a Red Blood Cell Transfusion or Hemoglobin ≤ 8.0 g/dL From Week 5 to End of the Efficacy Treatment Period

Description

Any red blood cell (RBC) transfusion (packed RBCs or whole blood) given or a hemoglobin ≤ 8.0 g/dL on or after study day 29 until the EOETP, inclusive.

Time Frame

Week 5 (day 29) to end of the efficacy treatment period (EOETP; defined as 21 days after either the last dose of study drug or the last dose of chemotherapy, whichever was later); median (range) duration of dosing was 10 (1 to 106) weeks in both groups.

Title

Number of Participants With Adverse Events of Special Interest

Description

Time Frame

From first dose of study drug until 30 days after last dose; the median (range) duration of treatment was 10 (1 to 106) weeks in both groups.

Title

Percentage of Participants With an Objective Tumor Response

Description

Time Frame

Day 1 to end of the efficacy treatment period (EOETP; defined as 21 days after either the last dose of study drug or the last dose of chemotherapy, whichever was later); median (range) duration of dosing was 10 (1 to 106) weeks in both groups.

Title

Number of Participants Who Developed Neutralizing Antibodies to Darbepoetin Alfa

Description

Developing antibody incidence was defined as neutralizing antibody positive postbaseline with a negative or no result at baseline.

Time Frame

Baseline and end of the efficacy treatment period (EOETP; defined as 21 days after either the last dose of study drug or the last dose of chemotherapy, whichever was later. the median (range) duration of treatment was 10 (1 to 106) weeks in both groups.

Title

Percentage of Participants With a Red Blood Cell Transfusion or Hemoglobin ≤ 8.0 g/dL From Week 1 to End of the Efficacy Treatment Period

Description

Any red blood cell (RBC) transfusion (packed RBCs or whole blood) given or a hemoglobin ≤ 8.0 g/dL on or after study day 1 until the EOETP, inclusive.

Time Frame

Week 1 to end of the efficacy treatment period (EOETP; defined as 21 days after either the last dose of study drug or the last dose of chemotherapy, whichever was later); the median (range) duration of treatment was 10 (1 to 106) weeks in both groups.

Title

Change From Baseline in Hemoglobin to End of Efficacy Treatment Period

Description

Post-baseline hemoglobin values within 28 days after a RBC transfusion were not be used in the calculation of change.

Time Frame

Baseline and end of the efficacy treatment period (EOETP; defined as 21 days after either the last dose of study drug or the last dose of chemotherapy, whichever was later); the median (range) duration of treatment was 10 (1 to 106) weeks in both groups.

10. Eligibility

Sex

All

Minimum Age & Unit of Time

18 Years

Accepts Healthy Volunteers

Eligibility Criteria

Inclusion Criteria: Subjects with stage IV NSCLC (not recurrent or re-staged). Expected to receive at least 2 additional cycles (at least 6 total weeks) of first line myelosuppressive cyclic chemotherapy after randomization. Subjects should not be expected to receive only maintenance chemotherapy. Eastern Cooperative Oncology Group performance status of 0 or 1 as assessed within 21 days prior to randomization. 18 years of age or older at screening. Life expectancy greater than 6 months based on the judgment of the investigator and documented during screening. Hemoglobin level less than or equal to 11.0 g/dL as assessed by the local laboratory; sample obtained within 7 days prior to randomization (retest in screening is acceptable). Adequate serum folate (greater than or equal to 2 ng/mL) and vitamin B12 (greater than or equal to 200 pg/mL) levels assessed by central laboratory (supplementation and retest acceptable) during screening. Subjects must have had a baseline scan (computed tomography [CT], magnetic resonance imaging [MRI], or positron emission tomography-computer tomography [PET/CT]) of the chest to assess disease burden before starting on first line chemotherapy for NSCLC and those images must have been reviewed by the investigator prior to randomization. If the scan was performed more than 28 days prior to randomization, an additional scan must be performed and reviewed by the investigator to confirm that the patient has not progressed before randomization. Before any study-specific procedure, the appropriate written informed consent must be obtained from the subject or a legally accepted representative. Exclusion Criteria: Known primary benign or malignant hematologic disorder which can cause anemia. History of, or current active cancer other than NSCLC, with the exception of curatively resected non-melanomatous skin cancer, curatively treated cervical carcinoma in situ, or other primary solid tumors curatively treated with no known active disease present and no curative treatment administered for the last 3 years. Received any prior adjuvant or neoadjuvant therapy for NSCLC. Subjects with a history of brain metastasis. Uncontrolled hypertension (systolic blood pressure [BP] > 160 mmHg or diastolic BP > 100 mmHg), or as determined by the investigator during screening. History of neutralizing antibody activity to recombinant human erythropoietin (rHuEPO) or darbepoetin alfa. Uncontrolled angina, uncontrolled heart failure, or uncontrolled cardiac arrhythmia as determined by the investigator at screening. Subjects with known myocardial infarction within 6 months prior to randomization. Subjects with a history of seizure disorder taking anti-seizure medication within 30 days prior to randomization. Clinically significant systemic infection or uncontrolled chronic inflammatory disease (eg, rheumatoid arthritis, inflammatory bowel disease) as determined by the investigator during screening. Known seropositivity for human immunodeficiency virus (HIV) or diagnosis of acquired immunodeficiency syndrome (AIDS), positive for hepatitis B surface antigen, or seropositive for hepatitis C virus History of pure red cell aplasia History of deep venous thrombosis or embolic event (eg, pulmonary embolism) within 6 months prior to randomization. Transferrin saturation < 20% and ferritin < 50 ng/mL as assessed by the central laboratory during screening. Subjects must have both to be excluded (supplementation and retest acceptable). Abnormal renal function (serum creatinine level > 2X upper limit of normal [ULN]) as assessed by the central laboratory during screening. Abnormal liver function (total bilirubin > 2X ULN or liver enzymes alanine aminotransferase [ALT] or aspartate aminotransferase [AST] > 2.5X ULN for subjects without liver metastasis or ≥ 5X ULN for subjects with liver metastasis) as assessed by the central laboratory during screening. Subjects with documented Gilbert's Disease may be eligible. Received any red blood cell (RBC) transfusion within 28 days prior to randomization. Plan to receive any RBC transfusion between randomization and study day 1. Known previous treatment failure to erythropoiesis stimulating agents (ESAs) (eg, rHuEPO, darbepoetin alfa). ESA therapy within the 28 days prior to randomization. Known hypersensitivity to recombinant ESAs or the excipients contained within the investigational product. Less than 30 days since receipt of any investigational product or device. Investigational use/receipt of a medicinal product or device that has been approved by the country's local regulatory authority for any indication is permitted. Subjects of reproductive potential who are pregnant, breast feeding or not willing to use effective contraceptive precautions during the study and for at least one month after the last dose of investigational product in the judgment of the investigator (including females of childbearing potential who are partners of male subjects). Previously randomized to this study. Investigator has concerns regarding the ability of the subject to give written informed consent and/or to comply with study procedures (including availability for follow up visits).

Overall Study Officials:

First Name & Middle Initial & Last Name & Degree

Organizational Affiliation

Amgen

Official's Role

Study Director

Facility Information:

Facility Name

Research Site

City

Anniston

State/Province

Alabama

ZIP/Postal Code

36207

Country

United States

Facility Name

Research Site

City

Birmingham

State/Province

Alabama

ZIP/Postal Code

35216

Country

United States

Facility Name

Research Site

City

Anchorage

State/Province

Alaska

ZIP/Postal Code

99508

Country

United States

Facility Name

Research Site

City

Tucson

State/Province

Arizona

ZIP/Postal Code

85704

Country

United States

Facility Name

Research Site

City

Fayetteville

State/Province

Arkansas

ZIP/Postal Code

72703

Country

United States

Facility Name

Research Site

City

Hot Springs

State/Province

Arkansas

ZIP/Postal Code

71913

Country

United States

Facility Name

Research Site

City

Jonesboro

State/Province

Arkansas

ZIP/Postal Code

72401

Country

United States

Facility Name

Research Site

City

Little Rock

State/Province

Arkansas

ZIP/Postal Code

72205

Country

United States

Facility Name

Research Site

City

Anaheim

State/Province

California

ZIP/Postal Code

92801

Country

United States

Facility Name

Research Site

City

Arcadia

State/Province

California

ZIP/Postal Code

91007

Country

United States

Facility Name

Research Site

City

Berkeley

State/Province

California

ZIP/Postal Code

94704

Country

United States

Facility Name

Research Site

City

Burbank

State/Province

California

ZIP/Postal Code

91505

Country

United States

Facility Name

Research Site

City

Downey

State/Province

California

ZIP/Postal Code

90241

Country

United States

Facility Name

Research Site

City

Fountain Valley

State/Province

California

ZIP/Postal Code

92708

Country

United States

Facility Name

Research Site

City

Fresno

State/Province

California

ZIP/Postal Code

93703

Country

United States

Facility Name

Research Site

City

Fresno

State/Province

California

ZIP/Postal Code

93720

Country

United States

Facility Name

Research Site

City

La Verne

State/Province

California

ZIP/Postal Code

91750

Country

United States

Facility Name

Research Site

City

Lancaster

State/Province

California

ZIP/Postal Code

93534

Country

United States

Facility Name

Research Site

City

Long Beach

State/Province

California

ZIP/Postal Code

90822

Country

United States

Facility Name

Research Site

City

Los Angeles

State/Province

California

ZIP/Postal Code

90024

Country

United States

Facility Name

Research Site

City

Los Angeles

State/Province

California

ZIP/Postal Code

90027

Country

United States

Facility Name

Research Site

City

Los Angeles

State/Province

California

ZIP/Postal Code

90048

Country

United States

Facility Name

Research Site

City

Merced

State/Province

California

ZIP/Postal Code

95348

Country

United States

Facility Name

Research Site

City

Mission Hills

State/Province

California

ZIP/Postal Code

91345

Country

United States

Facility Name

Research Site

City

Montebello

State/Province

California

ZIP/Postal Code

90640

Country

United States

Facility Name

Research Site

City

Oxnard

State/Province

California

ZIP/Postal Code

93030

Country

United States

Facility Name

Research Site

City

Palm Springs

State/Province

California

ZIP/Postal Code

92262

Country

United States

Facility Name

Research Site

City

Pismo Beach

State/Province

California

ZIP/Postal Code

93449

Country

United States

Facility Name

Research Site

City

Pomona

State/Province

California

ZIP/Postal Code

91767

Country

United States

Facility Name

Research Site

City

Redlands

State/Province

California

ZIP/Postal Code

92374

Country

United States

Facility Name

Research Site

City

Saint Helena

State/Province

California

ZIP/Postal Code

94574

Country

United States

Facility Name

Research Site

City

Salinas

State/Province

California

ZIP/Postal Code

93901

Country

United States

Facility Name

Research Site

City

San Diego

State/Province

California

ZIP/Postal Code

92161

Country

United States

Facility Name

Research Site

City

Santa Rosa

State/Province

California

ZIP/Postal Code

95403

Country

United States

Facility Name

Research Site

City

Simi Valley

State/Province

California

ZIP/Postal Code

93065

Country

United States

Facility Name

Research Site

City

Soquel

State/Province

California

ZIP/Postal Code

95073

Country

United States

Facility Name

Research Site

City

Torrance

State/Province

California

ZIP/Postal Code

90501

Country

United States

Facility Name

Research Site

City

Vallejo

State/Province

California

ZIP/Postal Code

94589

Country

United States

Facility Name

Research Site

City

West Covina

State/Province

California

ZIP/Postal Code

91790

Country

United States

Facility Name

Research Site

City

Denver

State/Province

Colorado

ZIP/Postal Code

80210

Country

United States

Facility Name

Research Site

City

Denver

State/Province

Colorado

ZIP/Postal Code

80218

Country

United States

Facility Name

Research Site

City

Englewood

State/Province

Colorado

ZIP/Postal Code

80113

Country

United States

Facility Name

Research Site

City

Bridgeport

State/Province

Connecticut

ZIP/Postal Code

06610

Country

United States

Facility Name

Research Site

City

Southington

State/Province

Connecticut

ZIP/Postal Code

06489

Country

United States

Facility Name

Research Site

City

Washington

State/Province

District of Columbia

ZIP/Postal Code

20037

Country

United States

Facility Name

Research Site

City

Washington

State/Province

District of Columbia

ZIP/Postal Code

20060

Country

United States

Facility Name

Research Site

City

Boynton Beach

State/Province

Florida

ZIP/Postal Code

33426

Country

United States

Facility Name

Research Site

City

Boynton Beach

State/Province

Florida

ZIP/Postal Code

33435

Country

United States

Facility Name

Research Site

City

Coral Springs

State/Province

Florida

ZIP/Postal Code

33065

Country

United States

Facility Name

Research Site

City

Daytona Beach

State/Province

Florida

ZIP/Postal Code

32114

Country

United States

Facility Name

Research Site

City

Fort Lauderdale

State/Province

Florida

ZIP/Postal Code

33316

Country

United States

Facility Name

Research Site

City

Holiday

State/Province

Florida

ZIP/Postal Code

34691

Country

United States

Facility Name

Research Site

City

Hollywood

State/Province

Florida

ZIP/Postal Code

33021

Country

United States

Facility Name

Research Site

City

Jacksonville

State/Province

Florida

ZIP/Postal Code

32256

Country

United States

Facility Name

Research Site

City

Kissimmee

State/Province

Florida

ZIP/Postal Code

34741

Country

United States

Facility Name

Research Site

City

Lake Worth

State/Province

Florida

ZIP/Postal Code

33461

Country

United States

Facility Name

Research Site

City

Lakeland

State/Province

Florida

ZIP/Postal Code

33805

Country

United States

Facility Name

Research Site

City

Lecanto

State/Province

Florida

ZIP/Postal Code

34461

Country

United States

Facility Name

Research Site

City

Miami

State/Province

Florida

ZIP/Postal Code

33133

Country

United States

Facility Name

Research Site

City

New Port Richey

State/Province

Florida

ZIP/Postal Code

34652

Country

United States

Facility Name

Research Site

City

New Port Richey

State/Province

Florida

ZIP/Postal Code

34655

Country

United States

Facility Name

Research Site

City

Orange City

State/Province

Florida

ZIP/Postal Code

32763

Country

United States

Facility Name

Research Site

City

Orlando

State/Province

Florida

ZIP/Postal Code

32806

Country

United States

Facility Name

Research Site

City

Pembroke Pines

State/Province

Florida

ZIP/Postal Code

33029

Country

United States

Facility Name

Research Site

City

Rockledge

State/Province

Florida

ZIP/Postal Code

32955

Country

United States

Facility Name

Research Site

City

Tamarac

State/Province

Florida

ZIP/Postal Code

33321

Country

United States

Facility Name

Research Site

City

The Villages

State/Province

Florida

ZIP/Postal Code

32159

Country

United States

Facility Name

Research Site

City

Titusville

State/Province

Florida

ZIP/Postal Code

32796

Country

United States

Facility Name

Research Site

City

Weston

State/Province

Florida

ZIP/Postal Code

33331

Country

United States

Facility Name

Research Site

City

Albany

State/Province

Georgia

ZIP/Postal Code

31701

Country

United States

Facility Name

Research Site

City

Augusta

State/Province

Georgia

ZIP/Postal Code

30901

Country

United States

Facility Name

Research Site

City

Stockbridge

State/Province

Georgia

ZIP/Postal Code

30281

Country

United States

Facility Name

Research Site

City

Thomasville

State/Province

Georgia

ZIP/Postal Code

31792

Country

United States

Facility Name

Research Site

City

Chicago

State/Province

Illinois

ZIP/Postal Code

60616

Country

United States

Facility Name

Research Site

City

Chicago

State/Province

Illinois

ZIP/Postal Code

60640

Country

United States

Facility Name

Research Site

City

Galesburg

State/Province

Illinois

ZIP/Postal Code

61401

Country

United States

Facility Name

Research Site

City

Gurnee

State/Province

Illinois

ZIP/Postal Code

60031

Country

United States

Facility Name

Research Site

City

Mount Vernon

State/Province

Illinois

ZIP/Postal Code

62864

Country

United States

Facility Name

Research Site

City

Skokie

State/Province

Illinois

ZIP/Postal Code

60077

Country

United States

Facility Name

Research Site

City

Indianapolis

State/Province

Indiana

ZIP/Postal Code

46219

Country

United States

Facility Name

Research Site

City

Michigan City

State/Province

Indiana

ZIP/Postal Code

46360

Country

United States

Facility Name

Research Site

City

Muncie

State/Province

Indiana

ZIP/Postal Code

47303

Country

United States

Facility Name

Research Site

City

Council Bluffs

State/Province

Iowa

ZIP/Postal Code

51503

Country

United States

Facility Name

Research Site

City

Dubuque

State/Province

Iowa

ZIP/Postal Code

52001

Country

United States

Facility Name

Research Site

City

Iowa City

State/Province

Iowa

ZIP/Postal Code

52242

Country

United States

Facility Name

Research Site

City

Sioux City

State/Province

Iowa

ZIP/Postal Code

51101

Country

United States

Facility Name

Research Site

City

Waterloo

State/Province

Iowa

ZIP/Postal Code

50702

Country

United States

Facility Name

Research Site

City

Hutchinson

State/Province

Kansas

ZIP/Postal Code

67502

Country

United States

Facility Name

Research Site

City

Wichita

State/Province

Kansas

ZIP/Postal Code

67214

Country

United States

Facility Name

Research Site

City

Ashland

State/Province

Kentucky

ZIP/Postal Code

41101

Country

United States

Facility Name

Research Site

City

Hazard

State/Province

Kentucky

ZIP/Postal Code

41701

Country

United States

Facility Name

Research Site

City

Louisville

State/Province

Kentucky

ZIP/Postal Code

40202

Country

United States

Facility Name

Research Site

City

Louisville

State/Province

Kentucky

ZIP/Postal Code

40207

Country

United States

Facility Name

Research Site

City

Morehead

State/Province

Kentucky

ZIP/Postal Code

40351

Country

United States

Facility Name

Research Site

City

Mount Sterling

State/Province

Kentucky

ZIP/Postal Code

40353

Country

United States

Facility Name

Research Site

City

Paducah

State/Province

Kentucky

ZIP/Postal Code

42001

Country

United States

Facility Name

Research Site

City

Paducah

State/Province

Kentucky

ZIP/Postal Code

42003

Country

United States

Facility Name

Research Site

City

Alexandria

State/Province

Louisiana

ZIP/Postal Code

71301

Country

United States

Facility Name

Research Site

City

Lafayette

State/Province

Louisiana

ZIP/Postal Code

70503

Country

United States

Facility Name

Research Site

City

Marrero

State/Province

Louisiana

ZIP/Postal Code

70072

Country

United States

Facility Name

Research Site

City

New Orleans

State/Province

Louisiana

ZIP/Postal Code

70112

Country

United States

Facility Name

Research Site

City

Ruston

State/Province

Louisiana

ZIP/Postal Code

71270

Country

United States

Facility Name

Research Site

City

Shreveport

State/Province

Louisiana

ZIP/Postal Code

71103

Country

United States

Facility Name

Research Site

City

Lewiston

State/Province

Maine

ZIP/Postal Code

04240

Country

United States

Facility Name

Research Site

City

Rockport

State/Province

Maine

ZIP/Postal Code

04856

Country

United States

Facility Name

Research Site

City

Baltimore

State/Province

Maryland

ZIP/Postal Code

21215

Country

United States

Facility Name

Research Site

City

Baltimore

State/Province

Maryland

ZIP/Postal Code

21218

Country

United States

Facility Name

Research Site

City

Baltimore

State/Province

Maryland

ZIP/Postal Code

21237

Country

United States

Facility Name

Research Site

City

Bethesda

State/Province

Maryland

ZIP/Postal Code

20817

Country

United States

Facility Name

Research Site

City

Chevy Chase

State/Province

Maryland

ZIP/Postal Code

20815

Country

United States

Facility Name

Research Site

City

Cumberland

State/Province

Maryland

ZIP/Postal Code

21502

Country

United States

Facility Name

Research Site

City

Frederick

State/Province

Maryland

ZIP/Postal Code

21701

Country

United States

Facility Name

Research Site

City

Hagerstown

State/Province

Maryland

ZIP/Postal Code

21742

Country

United States

Facility Name

Research Site

City

Towson

State/Province

Maryland

ZIP/Postal Code

21204

Country

United States

Facility Name

Research Site

City

Westminster

State/Province

Maryland

ZIP/Postal Code

21157

Country

United States

Facility Name

Research Site

City

Attleboro

State/Province

Massachusetts

ZIP/Postal Code

02703

Country

United States

Facility Name

Research Site

City

Boston

State/Province

Massachusetts

ZIP/Postal Code

02130

Country

United States

Facility Name

Research Site

City

Boston

State/Province

Massachusetts

ZIP/Postal Code

02135

Country

United States

Facility Name

Research Site

City

Brockton

State/Province

Massachusetts

ZIP/Postal Code

02302

Country

United States

Facility Name

Research Site

City

Cambridge

State/Province

Massachusetts

ZIP/Postal Code

02138

Country

United States

Facility Name

Research Site

City

Worcester

State/Province

Massachusetts

ZIP/Postal Code

01608

Country

United States

Facility Name

Research Site

City

Clarkston

State/Province

Michigan

ZIP/Postal Code

48346

Country

United States

Facility Name

Research Site

City

Grand Rapids

State/Province

Michigan

ZIP/Postal Code

49503

Country

United States

Facility Name

Research Site

City

Kalamazoo

State/Province

Michigan

ZIP/Postal Code

49048

Country

United States

Facility Name

Research Site

City

Southfield

State/Province

Michigan

ZIP/Postal Code

48075

Country

United States

Facility Name

Research Site

City

Southgate

State/Province

Michigan

ZIP/Postal Code

48195

Country

United States

Facility Name

Research Site

City

Willmar

State/Province

Minnesota

ZIP/Postal Code

56201

Country

United States

Facility Name

Research Site

City

Biloxi

State/Province

Mississippi

ZIP/Postal Code

39531

Country

United States

Facility Name

Research Site

City

Hattiesburg

State/Province

Mississippi

ZIP/Postal Code

39401

Country

United States

Facility Name

Research Site

City

Jackson

State/Province

Mississippi

ZIP/Postal Code

39216

Country

United States

Facility Name

Research Site

City

Tupelo

State/Province

Mississippi

ZIP/Postal Code

38801

Country

United States

Facility Name

Research Site

City

Columbia

State/Province

Missouri

ZIP/Postal Code

65201

Country

United States

Facility Name

Research Site

City

Jefferson City

State/Province

Missouri

ZIP/Postal Code

65101

Country

United States

Facility Name

Research Site

City

Kansas City

State/Province

Missouri

ZIP/Postal Code

64111

Country

United States

Facility Name

Research Site

City

Kansas City

State/Province

Missouri

ZIP/Postal Code

64132

Country

United States

Facility Name

Research Site

City

Saint Louis

State/Province

Missouri

ZIP/Postal Code

63110

Country

United States

Facility Name

Research Site

City

Saint Louis

State/Province

Missouri

ZIP/Postal Code

63136

Country

United States

Facility Name

Research Site

City

Springfield

State/Province

Missouri

ZIP/Postal Code

65807

Country

United States

Facility Name

Research Site

City

Great Falls

State/Province

Montana

ZIP/Postal Code

59405

Country

United States

Facility Name

Research Site

City

Kalispell

State/Province

Montana

ZIP/Postal Code

59901

Country

United States

Facility Name

Research Site

City

Grand Island

State/Province

Nebraska

ZIP/Postal Code

68803

Country

United States

Facility Name

Research Site

City

Omaha

State/Province

Nebraska

ZIP/Postal Code

68105

Country

United States

Facility Name

Research Site

City

Omaha

State/Province

Nebraska

ZIP/Postal Code

68106

Country

United States

Facility Name

Research Site

City

Henderson

State/Province

Nevada

ZIP/Postal Code

89052

Country

United States

Facility Name

Research Site

City

North Las Vegas

State/Province

Nevada

ZIP/Postal Code

89086

Country

United States

Facility Name

Research Site

City

Manchester

State/Province

New Hampshire

ZIP/Postal Code

03102

Country

United States

Facility Name

Research Site

City

Sparta

State/Province

New Jersey

ZIP/Postal Code

07871

Country

United States

Facility Name

Research Site

City

Teaneck

State/Province

New Jersey

ZIP/Postal Code

07666

Country

United States

Facility Name

Research Site

City

Vineland

State/Province

New Jersey

ZIP/Postal Code

08360

Country

United States

Facility Name

Research Site

City

Albuquerque

State/Province

New Mexico

ZIP/Postal Code

87109-4397

Country

United States

Facility Name

Research Site

City

Santa Fe

State/Province

New Mexico

ZIP/Postal Code

87505

Country

United States

Facility Name

Research Site

City

Albany

State/Province

New York

ZIP/Postal Code

12208

Country

United States

Facility Name

Research Site

City

Brooklyn

State/Province

New York

ZIP/Postal Code

11212

Country

United States

Facility Name

Research Site

City

Buffalo

State/Province

New York

ZIP/Postal Code

14215

Country

United States

Facility Name

Research Site

City

Glens Falls

State/Province

New York

ZIP/Postal Code

12801

Country

United States

Facility Name

Research Site

City

Goshen

State/Province

New York

ZIP/Postal Code

10924

Country

United States

Facility Name

Research Site

City

Lake Success

State/Province

New York

ZIP/Postal Code

11042

Country

United States

Facility Name

Research Site

City

Latham

State/Province

New York

ZIP/Postal Code

12110-0610

Country

United States

Facility Name

Research Site

City

Nyack

State/Province

New York

ZIP/Postal Code

10960

Country

United States

Facility Name

Research Site

City

Poughkeepsie

State/Province

New York

ZIP/Postal Code

12601

Country

United States

Facility Name

Research Site

City

Staten Island

State/Province

New York

ZIP/Postal Code

10301

Country

United States

Facility Name

Research Site

City

Staten Island

State/Province

New York

ZIP/Postal Code

10310

Country

United States

Facility Name

Research Site

City

Syracuse

State/Province

New York

ZIP/Postal Code

13210

Country

United States

Facility Name

Research Site

City

Valhalla

State/Province

New York

ZIP/Postal Code

10595

Country

United States

Facility Name

Research Site

City

Asheboro

State/Province

North Carolina

ZIP/Postal Code

27203

Country

United States

Facility Name

Research Site

City

Asheville

State/Province

North Carolina

ZIP/Postal Code

28801

Country

United States

Facility Name

Research Site

City

Burlington

State/Province

North Carolina

ZIP/Postal Code

27215

Country

United States

Facility Name

Research Site

City

Concord

State/Province

North Carolina

ZIP/Postal Code

28025

Country

United States

Facility Name

Research Site

City

Durham

State/Province

North Carolina

ZIP/Postal Code

27704

Country

United States

Facility Name

Research Site

City

Goldsboro

State/Province

North Carolina

ZIP/Postal Code

27534

Country

United States

Facility Name

Research Site

City

Greenville

State/Province

North Carolina

ZIP/Postal Code

27834

Country

United States

Facility Name

Research Site

City

Hendersonville

State/Province

North Carolina

ZIP/Postal Code

28791

Country

United States

Facility Name

Research Site

City

Hickory

State/Province

North Carolina

ZIP/Postal Code

28602

Country

United States

Facility Name

Research Site

City

High Point

State/Province

North Carolina

ZIP/Postal Code

27262

Country

United States

Facility Name

Research Site

City

Huntersville

State/Province

North Carolina

ZIP/Postal Code

28078

Country

United States

Facility Name

Research Site

City

Kinston

State/Province

North Carolina

ZIP/Postal Code

28501

Country

United States

Facility Name

Research Site

City

Pinehurst

State/Province

North Carolina

ZIP/Postal Code

28374

Country

United States

Facility Name

Research Site

City

Raleigh

State/Province

North Carolina

ZIP/Postal Code

27607

Country

United States

Facility Name

Research Site

City

Washington

State/Province

North Carolina

ZIP/Postal Code

27889

Country

United States

Facility Name

Research Site

City

Bismarck

State/Province

North Dakota

ZIP/Postal Code

58501

Country

United States

Facility Name

Research Site

City

Akron

State/Province

Ohio

ZIP/Postal Code

44304

Country

United States

Facility Name

Research Site

City

Columbus

State/Province

Ohio

ZIP/Postal Code

43235

Country

United States

Facility Name

Research Site

City

Dayton

State/Province

Ohio

ZIP/Postal Code

45428

Country

United States

Facility Name

Research Site

City

Massillon

State/Province

Ohio

ZIP/Postal Code

44646

Country

United States

Facility Name

Research Site

City

Middletown

State/Province

Ohio

ZIP/Postal Code

45042

Country

United States

Facility Name

Research Site

City

Port Clinton

State/Province

Ohio

ZIP/Postal Code

43452

Country

United States

Facility Name

Research Site

City

Sylvania

State/Province

Ohio

ZIP/Postal Code

43560

Country

United States

Facility Name

Research Site

City

Wooster

State/Province

Ohio

ZIP/Postal Code

44691

Country

United States

Facility Name

Research Site

City

Oklahoma City

State/Province

Oklahoma

ZIP/Postal Code

73102

Country

United States

Facility Name

Research Site

City

Tulsa

State/Province

Oklahoma

ZIP/Postal Code

74104

Country

United States

Facility Name

Research Site

City

Bethlehem

State/Province

Pennsylvania

ZIP/Postal Code

18015

Country

United States

Facility Name

Research Site

City

Gettysburg

State/Province

Pennsylvania

ZIP/Postal Code

17325

Country

United States

Facility Name

Research Site

City

Langhorne

State/Province

Pennsylvania

ZIP/Postal Code

19047

Country

United States

Facility Name

Research Site

City

Philadelphia

State/Province

Pennsylvania

ZIP/Postal Code

19102

Country

United States

Facility Name

Research Site

City

Philadelphia

State/Province

Pennsylvania

ZIP/Postal Code

19106

Country

United States

Facility Name

Research Site

City

Philadelphia

State/Province

Pennsylvania

ZIP/Postal Code

19107

Country

United States

Facility Name

Research Site

City

Philadelphia

State/Province

Pennsylvania

ZIP/Postal Code

19140

Country

United States

Facility Name

Research Site

City

Philadelphia

State/Province

Pennsylvania

ZIP/Postal Code

19141

Country

United States

Facility Name

Research Site

City

Pittsburgh

State/Province

Pennsylvania

ZIP/Postal Code

15240

Country

United States

Facility Name

Research Site

City

Upland

State/Province

Pennsylvania

ZIP/Postal Code

19013

Country

United States

Facility Name

Research Site

City

Willow Grove

State/Province

Pennsylvania

ZIP/Postal Code

19090

Country

United States

Facility Name

Research Site

City

Wynnewood

State/Province

Pennsylvania

ZIP/Postal Code

19096

Country

United States

Facility Name

Research Site

City

Pawtucket

State/Province

Rhode Island

ZIP/Postal Code

02860

Country

United States

Facility Name

Research Site

City

Providence

State/Province

Rhode Island

ZIP/Postal Code

02908

Country

United States

Facility Name

Research Site

City

Woonsocket

State/Province

Rhode Island

ZIP/Postal Code

02895

Country

United States

Facility Name

Research Site

City

Aiken

State/Province

South Carolina

ZIP/Postal Code

29801

Country

United States

Facility Name

Research Site

City

Charleston

State/Province

South Carolina

ZIP/Postal Code

29406

Country

United States

Facility Name

Research Site

City

Charleston

State/Province

South Carolina

ZIP/Postal Code

29414

Country

United States

Facility Name

Research Site

City

Columbia

State/Province

South Carolina

ZIP/Postal Code

29210

Country

United States

Facility Name

Research Site

City

Hilton Head Island

State/Province

South Carolina

ZIP/Postal Code

29926

Country

United States

Facility Name

Research Site

City

Myrtle Beach

State/Province

South Carolina

ZIP/Postal Code

29572

Country

United States

Facility Name

Research Site

City

Sumter

State/Province

South Carolina

ZIP/Postal Code

29150

Country

United States

Facility Name

Research Site

City

Aberdeen

State/Province

South Dakota

ZIP/Postal Code

57401

Country

United States

Facility Name

Research Site

City

Sioux Falls

State/Province

South Dakota

ZIP/Postal Code

57105

Country

United States

Facility Name

Research Site

City

Watertown

State/Province

South Dakota

ZIP/Postal Code

57201

Country

United States

Facility Name

Research Site

City

Johnson City

State/Province

Tennessee

ZIP/Postal Code

37604

Country

United States

Facility Name

Research Site

City

Knoxville

State/Province

Tennessee

ZIP/Postal Code

37920

Country

United States

Facility Name

Research Site

City

Memphis

State/Province

Tennessee

ZIP/Postal Code

38104

Country

United States

Facility Name

Research Site

City

Memphis

State/Province

Tennessee

ZIP/Postal Code

38120

Country

United States

Facility Name

Research Site

City

Nashville

State/Province

Tennessee

ZIP/Postal Code

37203

Country

United States

Facility Name

Research Site

City

Abilene

State/Province

Texas

ZIP/Postal Code

79606-5208

Country

United States

Facility Name

Research Site

City

Amarillo

State/Province

Texas

ZIP/Postal Code

79106

Country

United States

Facility Name

Research Site

City

Austin

State/Province

Texas

ZIP/Postal Code

78731

Country

United States

Facility Name

Research Site

City

Beaumont

State/Province

Texas

ZIP/Postal Code

77702

Country

United States

Facility Name

Research Site

City

Bedford

State/Province

Texas

ZIP/Postal Code

76022

Country

United States

Facility Name

Research Site

City

Bryan

State/Province

Texas

ZIP/Postal Code

77802

Country

United States

Facility Name

Research Site

City

Corpus Christi

State/Province

Texas

ZIP/Postal Code

78405

Country

United States

Facility Name

Research Site

City

Corpus Christi

State/Province

Texas

ZIP/Postal Code

78412

Country

United States

Facility Name

Research Site

City

Dallas

State/Province

Texas

ZIP/Postal Code

75230-2510

Country

United States

Facility Name

Research Site

City

Dallas

State/Province

Texas

ZIP/Postal Code

75231

Country

United States

Facility Name

Research Site

City

Dallas

State/Province

Texas

ZIP/Postal Code

75237

Country

United States

Facility Name

Research Site

City

El Paso

State/Province

Texas

ZIP/Postal Code

79905

Country

United States

Facility Name

Research Site

City

El Paso

State/Province

Texas

ZIP/Postal Code

79915

Country

United States

Facility Name

Research Site

City

Fort Worth

State/Province

Texas

ZIP/Postal Code

76104

Country

United States

Facility Name

Research Site

City

Garland

State/Province

Texas

ZIP/Postal Code

75042

Country

United States

Facility Name

Research Site

City

Harlingen

State/Province

Texas

ZIP/Postal Code

78550

Country

United States

Facility Name

Research Site

City

Houston

State/Province

Texas

ZIP/Postal Code

77055

Country

United States

Facility Name

Research Site

City

Irving

State/Province

Texas

ZIP/Postal Code

75063

Country

United States

Facility Name

Research Site

City

Longview

State/Province

Texas

ZIP/Postal Code

75601

Country

United States

Facility Name

Research Site

City

McAllen

State/Province

Texas

ZIP/Postal Code

78503-1298

Country

United States

Facility Name

Research Site

City

Mesquite

State/Province

Texas

ZIP/Postal Code

75150

Country

United States

Facility Name

Research Site

City

Midland

State/Province

Texas

ZIP/Postal Code

79701-5946

Country

United States

Facility Name

Research Site

City

Paris

State/Province

Texas

ZIP/Postal Code

75460-5004

Country

United States

Facility Name

Research Site

City

Richardson

State/Province

Texas

ZIP/Postal Code

75082

Country

United States

Facility Name

Research Site

City

Round Rock

State/Province

Texas

ZIP/Postal Code

78665

Country

United States

Facility Name

Research Site

City

San Antonio

State/Province

Texas

ZIP/Postal Code

78217

Country

United States

Facility Name

Research Site

City

San Antonio

State/Province

Texas

ZIP/Postal Code

78229

Country

United States

Facility Name

Research Site

City

Sherman

State/Province

Texas

ZIP/Postal Code

75090

Country

United States

Facility Name

Research Site

City

Southlake

State/Province

Texas

ZIP/Postal Code

76092

Country

United States

Facility Name

Research Site

City

Sugar Land

State/Province

Texas

ZIP/Postal Code

77479

Country

United States

Facility Name

Research Site

City

Temple

State/Province

Texas

ZIP/Postal Code

76508

Country

United States

Facility Name

Research Site

City

The Woodlands

State/Province

Texas

ZIP/Postal Code

77380

Country

United States

Facility Name

Research Site

City

Tyler

State/Province

Texas

ZIP/Postal Code

75701

Country

United States

Facility Name

Research Site

City

Tyler

State/Province

Texas

ZIP/Postal Code

75702

Country

United States

Facility Name

Research Site

City

Waco

State/Province

Texas

ZIP/Postal Code

76712

Country

United States

Facility Name

Research Site

City

Webster

State/Province

Texas

ZIP/Postal Code

77598

Country

United States

Facility Name

Research Site

City

Wichita Falls

State/Province

Texas

ZIP/Postal Code

76310

Country

United States

Facility Name

Research Site

City

Ogden

State/Province

Utah

ZIP/Postal Code

84403

Country

United States

Facility Name

Research Site

City

White River Junction

State/Province

Vermont

ZIP/Postal Code

05009

Country

United States

Facility Name

Research Site

City

Christiansburg

State/Province

Virginia

ZIP/Postal Code

24073

Country

United States

Facility Name

Research Site

City

Fairfax

State/Province

Virginia

ZIP/Postal Code

22031

Country

United States

Facility Name

Research Site

City

Lynchburg

State/Province

Virginia

ZIP/Postal Code

24501

Country

United States

Facility Name

Research Site

City

Newport News

State/Province

Virginia

ZIP/Postal Code

23601

Country

United States

Facility Name

Research Site

City

Portsmouth

State/Province

Virginia

ZIP/Postal Code

23704

Country

United States

Facility Name

Research Site

City

Bremerton

State/Province

Washington

ZIP/Postal Code

98310

Country

United States

Facility Name

Research Site

City

Burien

State/Province

Washington

ZIP/Postal Code

98166

Country

United States

Facility Name

Research Site

City

Edmonds

State/Province

Washington

ZIP/Postal Code

98026

Country

United States

Facility Name

Research Site

City

Seattle

State/Province

Washington

ZIP/Postal Code

98133

Country

United States

Facility Name

Research Site

City

Spokane

State/Province

Washington

ZIP/Postal Code

99202

Country

United States

Facility Name

Research Site

City

Spokane

State/Province

Washington

ZIP/Postal Code

99208

Country

United States

Facility Name

Research Site

City

Spokane

State/Province

Washington

ZIP/Postal Code

99218

Country

United States

Facility Name

Research Site

City

Tacoma

State/Province

Washington

ZIP/Postal Code

98405

Country

United States

Facility Name

Research Site

City

Vancouver

State/Province

Washington

ZIP/Postal Code

98684

Country

United States

Facility Name

Research Site

City

Yakima

State/Province

Washington

ZIP/Postal Code

98902

Country

United States

Facility Name

Research Site

City

Green Bay

State/Province

Wisconsin

ZIP/Postal Code

54311

Country

United States

Facility Name

Research Site

City

Janesville

State/Province

Wisconsin

ZIP/Postal Code

53548

Country

United States

Facility Name

Research Site

City

Milwaukee

State/Province

Wisconsin

ZIP/Postal Code

53211

Country

United States

Facility Name

Research Site

City

Quilmes

State/Province

Buenos Aires

ZIP/Postal Code

B1878DVB

Country

Argentina

Facility Name

Research Site

City

Quilmes

State/Province

Buenos Aires

ZIP/Postal Code

B1878GEG

Country

Argentina

Facility Name

Research Site

City

Cordoba

State/Province

Córdoba

ZIP/Postal Code

X5006HBF

Country

Argentina

Facility Name

Research Site

City

Ciudad Autónoma de Buenos Aires

State/Province

Distrito Federal

ZIP/Postal Code

C1019ABS

Country

Argentina

Facility Name

Research Site

City

Ciudad Autónoma de Buenos Aires

State/Province

Distrito Federal

ZIP/Postal Code

C1185AAT

Country

Argentina

Facility Name

Research Site

City

San Salvador de Jujuy

State/Province

Jujuy

ZIP/Postal Code

4600

Country

Argentina

Facility Name

Research Site

City

Rosario

State/Province

Santa Fe

ZIP/Postal Code

S2000CVD

Country

Argentina

Facility Name

Research Site

City

Rosario

State/Province

Santa Fe

ZIP/Postal Code

S2002KDS

Country

Argentina

Facility Name

Research Site

City

San Miguel de Tucuman

State/Province

Tucuman

ZIP/Postal Code

T4000GTB

Country

Argentina

Facility Name

Research Site

City

Buenos Aires

ZIP/Postal Code

C1180AAX

Country

Argentina

Facility Name

Research Site

City

La Rioja

ZIP/Postal Code

F5300COE

Country

Argentina

Facility Name

Research Site

City

Santa Fe

ZIP/Postal Code

S3000FFU

Country

Argentina

Facility Name

Research Site

City

Steyr

ZIP/Postal Code

4400

Country

Austria

Facility Name

Research Site

City

Wien

ZIP/Postal Code

1090

Country

Austria

Facility Name

Research Site

City

Ieper

ZIP/Postal Code

8900

Country

Belgium

Facility Name

Research Site

City

Libramont

ZIP/Postal Code

6800

Country

Belgium

Facility Name

Research Site

City

Liège

ZIP/Postal Code

4000

Country

Belgium

Facility Name

Research Site

City

Namur

ZIP/Postal Code

5000

Country

Belgium

Facility Name

Research Site

City

Ottignies

ZIP/Postal Code

1340

Country

Belgium

Facility Name

Research Site

City

Salvador

State/Province

Bahia

ZIP/Postal Code

40170-110

Country

Brazil

Facility Name

Research Site

City

Fortaleza

State/Province

Ceará

ZIP/Postal Code

60336-045

Country

Brazil

Facility Name

Research Site

City

Fortaleza

State/Province

Ceará

ZIP/Postal Code

60430-230

Country

Brazil

Facility Name

Research Site

City

Brasilia

State/Province

Distrito Federal

ZIP/Postal Code

72110-150

Country

Brazil

Facility Name

Research Site

City

Cachoeiro de Itapemirim

State/Province

Espírito Santo

ZIP/Postal Code

29308-020

Country

Brazil

Facility Name

Research Site

City

Campo Grande

State/Province

Mato Grosso Do Sul

ZIP/Postal Code

79010-050

Country

Brazil

Facility Name

Research Site

City

Belo Horizonte

State/Province

Minas Gerais

ZIP/Postal Code

30110-090

Country

Brazil

Facility Name

Research Site

City

Belo Horizonte

State/Province

Minas Gerais

ZIP/Postal Code

30150-281

Country

Brazil

Facility Name

Research Site

City

Belo Horizonte

State/Province

Minas Gerais

ZIP/Postal Code

30150-321

Country

Brazil

Facility Name

Research Site

City

Belo Horizonte

State/Province

Minas Gerais

ZIP/Postal Code

30285-000

Country

Brazil

Facility Name

Research Site

City

Curitba

State/Province

Paraná

ZIP/Postal Code

81520-060

Country

Brazil

Facility Name

Research Site

City

Curitiba

State/Province

Paraná

ZIP/Postal Code

80010-030

Country

Brazil

Facility Name

Research Site

City

Curitiba

State/Province

Paraná

ZIP/Postal Code

80530-010

Country

Brazil

Facility Name

Research Site

City

Londrina

State/Province

Paraná

ZIP/Postal Code

86050-190

Country

Brazil

Facility Name

Research Site

City

Belem

State/Province

Pará

ZIP/Postal Code

66053-000

Country

Brazil

Facility Name

Research Site

City

Ijui

State/Province

Rio Grande Do Sul

ZIP/Postal Code

98700-000

Country

Brazil

Facility Name

Research Site

City

Passo Fundo

State/Province

Rio Grande Do Sul

ZIP/Postal Code

99010-260

Country

Brazil

Facility Name

Research Site

City

Pelotas

State/Province

Rio Grande Do Sul

ZIP/Postal Code

96015-280

Country

Brazil

Facility Name

Research Site

City

Porto Alegre

State/Province

Rio Grande Do Sul

ZIP/Postal Code

90035-001

Country

Brazil

Facility Name

Research Site

City

Porto Alegre

State/Province

Rio Grande Do Sul

ZIP/Postal Code

90610-000

Country

Brazil

Facility Name

Research Site

City

Porto Alegre

State/Province

Rio Grande Do Sul

ZIP/Postal Code

90840-440

Country

Brazil

Facility Name

Research Site

City

Itajaí

State/Province

Santa Catarina

ZIP/Postal Code

88301-220

Country

Brazil

Facility Name

Research Site

City

Ribeirao Preto

State/Province

São Paulo

ZIP/Postal Code

14015-130

Country

Brazil

Facility Name

Research Site

City

Santo Andre

State/Province

São Paulo

ZIP/Postal Code

09060-650

Country

Brazil

Facility Name

Research Site

City

Santo Andre

State/Province

São Paulo

ZIP/Postal Code

09090-780

Country

Brazil

Facility Name

Research Site

City

Sao Jose dos Campos

State/Province

São Paulo

ZIP/Postal Code

12245-750

Country

Brazil

Facility Name

Research Site

City

Sao Paulo

State/Province

São Paulo

ZIP/Postal Code

01221-020

Country

Brazil

Facility Name

Research Site

City

Sao Paulo

State/Province

São Paulo

ZIP/Postal Code

08270-070

Country

Brazil

Facility Name

Research Site

City

Rio de Janeiro

ZIP/Postal Code

22260-020

Country

Brazil

Facility Name

Research Site

City

Rio de Janeiro

ZIP/Postal Code

22640-000

Country

Brazil

Facility Name

Research Site

City

Rio de Janeiro

ZIP/Postal Code

22793-080

Country

Brazil

Facility Name

Research Site

City

São Paulo

ZIP/Postal Code

01246-000

Country

Brazil

Facility Name

Research Site

City

Ruse

ZIP/Postal Code

7002

Country

Bulgaria

Facility Name

Research Site

City

Sofia

ZIP/Postal Code

1233

Country

Bulgaria

Facility Name

Research Site

City

Sofia

ZIP/Postal Code

1784

Country

Bulgaria

Facility Name

Research Site

City

Varna

ZIP/Postal Code

9000

Country

Bulgaria

Facility Name

Research Site

City

Moncton

State/Province

New Brunswick

ZIP/Postal Code

E1C 6Z8

Country

Canada

Facility Name

Research Site

City

Oshawa

State/Province

Ontario

ZIP/Postal Code

L1G 2B9

Country

Canada

Facility Name

Research Site

City

Toronto

State/Province

Ontario

ZIP/Postal Code

M9N 1N8

Country

Canada

Facility Name

Research Site

City

Montreal

State/Province

Quebec

ZIP/Postal Code

H2W 1S6

Country

Canada

Facility Name

Research Site

City

Saint-Jerome

State/Province

Quebec

ZIP/Postal Code

J7Z 5T3

Country

Canada

Facility Name

Research Site

City

Temuco

State/Province

Cautín

ZIP/Postal Code

4810469

Country

Chile

Facility Name

Research Site

City

Renaca

State/Province

Valparaíso

Country

Chile

Facility Name

Research Site

City

Santiago

ZIP/Postal Code

7500006

Country

Chile

Facility Name

Research Site

City

Santiago

ZIP/Postal Code

7571831

Country

Chile

Facility Name

Research Site

City

Santiago

ZIP/Postal Code

8380455

Country

Chile

Facility Name

Research Site

City

Beijing

State/Province

Beijing

ZIP/Postal Code

100191

Country

China

Facility Name

Research Site

City

Chongqing

State/Province

Chongqing

ZIP/Postal Code

400038

Country

China

Facility Name

Research Site

City

Fuzhou

State/Province

Fujian

ZIP/Postal Code

350001

Country

China

Facility Name

Research Site

City

Fuzhou

State/Province

Fujian

ZIP/Postal Code

350025

Country

China

Facility Name

Research Site

City

Lanzhou

State/Province

Gansu

ZIP/Postal Code

730050

Country

China

Facility Name

Research Site

City

Guangzhou

State/Province

Guangdong

ZIP/Postal Code

510010

Country

China

Facility Name

Research Site

City

Guangzhou

State/Province

Guangdong

ZIP/Postal Code

510060

Country

China

Facility Name

Research Site

City

Guangzhou

State/Province

Guangdong

ZIP/Postal Code

510120

Country

China

Facility Name

Research Site

City

Zhongshan

State/Province

Guangdong

ZIP/Postal Code

528403

Country

China

Facility Name

Research Site

City

Haikou

State/Province

Hainan

ZIP/Postal Code

570102

Country

China

Facility Name

Research Site

City

Haikou

State/Province

Hainan

ZIP/Postal Code

570311

Country

China

Facility Name

Research Site

City

Shijiazhuang

State/Province

Hebei

ZIP/Postal Code

050011

Country

China

Facility Name

Research Site

City

Harbin

State/Province

Heilongjiang

ZIP/Postal Code

150081

Country

China

Facility Name

Research Site

City

Wuhan

State/Province

Hubei

ZIP/Postal Code

430030

Country

China

Facility Name

Research Site

City

Wuhan

State/Province

Hubei

ZIP/Postal Code

430070

Country

China

Facility Name

Research Site

City

Changsha

State/Province

Hunan

ZIP/Postal Code

410013

Country

China

Facility Name

Research Site

City

Nanjing

State/Province

Jiangsu

ZIP/Postal Code

210002

Country

China

Facility Name

Research Site

City

Nanjing

State/Province

Jiangsu

ZIP/Postal Code

210009

Country

China

Facility Name

Research Site

City

Suzhou

State/Province

Jiangsu

ZIP/Postal Code

215004

Country

China

Facility Name

Research Site

City

Nanchang

State/Province

Jiangxi

ZIP/Postal Code

330006

Country

China

Facility Name

Research Site

City

Changchun

State/Province

Jilin

ZIP/Postal Code

130012

Country

China

Facility Name

Research Site

City

Changchun

State/Province

Jilin

ZIP/Postal Code

130021

Country

China

Facility Name

Research Site

City

Dalian

State/Province

Liaoning

ZIP/Postal Code

116027

Country

China

Facility Name

Research Site

City

Shenyang

State/Province

Liaoning

ZIP/Postal Code

110016

Country

China

Facility Name

Research Site

City

Shenyang

State/Province

Liaoning

ZIP/Postal Code

110042

Country

China

Facility Name

Research Site

City

XI An

State/Province

Shaanxi

ZIP/Postal Code

710038

Country

China

Facility Name

Research Site

City

Jinan

State/Province

Shandong

ZIP/Postal Code

250013

Country

China

Facility Name

Research Site

City

Chengdu

State/Province

Sichuan

ZIP/Postal Code

610041

Country

China

Facility Name

Research Site

City

Chengdu

State/Province

Sichuan

ZIP/Postal Code

610072

Country

China

Facility Name

Research Site

City

Urumqi

State/Province

Xinjiang

ZIP/Postal Code

830000

Country

China

Facility Name

Research Site

City

Kunming

State/Province

Yunnan

ZIP/Postal Code

650032

Country

China

Facility Name

Research Site

City

Kunming

State/Province

Yunnan

ZIP/Postal Code

650118

Country

China

Facility Name

Research Site

City

Hangzhou

State/Province

Zhejiang

ZIP/Postal Code

310009

Country

China

Facility Name

Research Site

City

Hangzhou

State/Province

Zhejiang

ZIP/Postal Code

310016

Country

China

Facility Name

Research Site

City

Hangzhou

State/Province

Zhejiang

ZIP/Postal Code

310022

Country

China

Facility Name

Research Site

City

Beijing

ZIP/Postal Code

100020

Country

China

Facility Name

Research Site

City

Beijing

ZIP/Postal Code

100021

Country

China

Facility Name

Research Site

City

Beijing

ZIP/Postal Code

100029

Country

China

Facility Name

Research Site

City

Beijing

ZIP/Postal Code

100142

Country

China

Facility Name

Research Site

City

Beijing

ZIP/Postal Code

101149

Country

China

Facility Name

Research Site

City

Chongqing

ZIP/Postal Code

400030

Country

China

Facility Name

Research Site

City

Chongqing

ZIP/Postal Code

400037

Country

China

Facility Name

Research Site

City

Shanghai

ZIP/Postal Code

200003

Country

China

Facility Name

Research Site

City

Shanghai

ZIP/Postal Code

200025

Country

China

Facility Name

Research Site

City

Shanghai

ZIP/Postal Code

200032

Country

China

Facility Name

Research Site

City

Shanghai

ZIP/Postal Code

200092

Country

China

Facility Name

Research Site

City

Shanghai

ZIP/Postal Code

200127

Country

China

Facility Name

Research Site

City

Rijeka

ZIP/Postal Code

51000

Country

Croatia

Facility Name

Research Site

City

Zagreb

ZIP/Postal Code

10000

Country

Croatia

Facility Name

Research Site

City

Benesov U Prahy

ZIP/Postal Code

256 30

Country

Czechia

Facility Name

Research Site

City

Horovice

ZIP/Postal Code

268 31

Country

Czechia

Facility Name

Research Site

City

Kutna Hora

ZIP/Postal Code

284 01

Country

Czechia

Facility Name

Research Site

City

Kyjov

ZIP/Postal Code

697 33

Country

Czechia

Facility Name

Research Site

City

Nova Ves pod Plesi

ZIP/Postal Code

262 04

Country

Czechia

Facility Name

Research Site

City

Ostrava-Poruba

ZIP/Postal Code

708 52

Country

Czechia

Facility Name

Research Site

City

Praha 4

ZIP/Postal Code

140 59

Country

Czechia

Facility Name

Research Site

City

Praha 8

ZIP/Postal Code

180 81

Country

Czechia

Facility Name

Research Site

City

Pribram

ZIP/Postal Code

261 01

Country

Czechia

Facility Name

Research Site

City

Bad Berka

ZIP/Postal Code

99437

Country

Germany

Facility Name

Research Site

City

Köln-Merheim

ZIP/Postal Code

51109

Country

Germany

Facility Name

Research Site

City

Moers

ZIP/Postal Code

47441

Country

Germany

Facility Name

Research Site

City

München

ZIP/Postal Code

80336

Country

Germany

Facility Name

Research Site

City

Münster

ZIP/Postal Code

48149

Country

Germany

Facility Name

Research Site

City

Athens

ZIP/Postal Code

11527

Country

Greece

Facility Name

Research Site

City

Athens

ZIP/Postal Code

12462

Country

Greece

Facility Name

Research Site

City

Athens

ZIP/Postal Code

14564

Country

Greece

Facility Name

Research Site

City

Chania

ZIP/Postal Code

73300

Country

Greece

Facility Name

Research Site

City

Larissa

ZIP/Postal Code

41110

Country

Greece

Facility Name

Research Site

City

Nea Kifissia, Athens

ZIP/Postal Code

14564

Country

Greece

Facility Name

Research Site

City

Piraeus

ZIP/Postal Code

18537

Country

Greece

Facility Name

Research Site

City

Thessaloniki

ZIP/Postal Code

57010

Country

Greece

Facility Name

Research Site

City

Hong Kong

Country

Hong Kong

Facility Name

Research Site

City

Kowloon

Country

Hong Kong

Facility Name

Research Site

City

New Territories

Country

Hong Kong

Facility Name

Research Site

City

New Delhi

State/Province

Delhi

ZIP/Postal Code

110 030

Country

India

Facility Name

Research Site

City

Panaji

State/Province

Goa

ZIP/Postal Code

403 001

Country

India

Facility Name

Research Site

City

Ahmedabad

State/Province

Gujarat

ZIP/Postal Code

380 009

Country

India

Facility Name

Research Site

City

Bangalore

State/Province

Karnataka

ZIP/Postal Code

560 054

Country

India

Facility Name

Research Site

City

Mangalore

State/Province

Karnataka

ZIP/Postal Code

575 001

Country

India

Facility Name

Research Site

City

Kochi

State/Province

Kerala

ZIP/Postal Code

682 304

Country

India

Facility Name

Research Site

City

Bhopal

State/Province

Madhya Pradesh

ZIP/Postal Code

462 001

Country

India

Facility Name

Research Site

City

Ahmednagar

State/Province

Maharashtra

ZIP/Postal Code

413 736

Country

India

Facility Name

Research Site

City

Aurangabad

State/Province

Maharashtra

ZIP/Postal Code

431 001

Country

India

Facility Name

Research Site

City

Thane

State/Province

Maharashtra

ZIP/Postal Code

400 607

Country

India

Facility Name

Research Site

City

Jaipur

State/Province

Rajasthan

ZIP/Postal Code

302 004

Country

India

Facility Name

Research Site

City

Jaipur

State/Province

Rajasthan

ZIP/Postal Code

302 013

Country

India

Facility Name

Research Site

City

Chennai

State/Province

Tamil Nadu

ZIP/Postal Code

600 018

Country

India

Facility Name

Research Site

City

Madurai

State/Province

Tamil Nadu

ZIP/Postal Code

625 107

Country

India

Facility Name

Research Site

City

Kolkata

State/Province

West Bengal

ZIP/Postal Code

700 026

Country

India

Facility Name

Research Site

City

Bangalore

ZIP/Postal Code

560 029

Country

India

Facility Name

Research Site

City

Dublin

ZIP/Postal Code

Country

Ireland

Facility Name

Research Site

City

Dublin

ZIP/Postal Code

Country

Ireland

Facility Name

Research Site

City

Jerusalem

ZIP/Postal Code

91120

Country

Israel

Facility Name

Research Site

City

Kefar Saba

ZIP/Postal Code

44281

Country

Israel

Facility Name

Research Site

City

Poria Eylit

ZIP/Postal Code

15208

Country

Israel

Facility Name

Research Site

City

Rehovot

ZIP/Postal Code

76100

Country

Israel

Facility Name

Research Site

City

Tel Aviv

ZIP/Postal Code

64239

Country

Israel

Facility Name

Research Site

City

Catania

ZIP/Postal Code

95122

Country

Italy

Facility Name

Research Site

City

Faenza RA

ZIP/Postal Code

48018

Country

Italy

Facility Name

Research Site

City

Grosseto

ZIP/Postal Code

58100

Country

Italy

Facility Name

Research Site

City

Lecce

ZIP/Postal Code

73100

Country

Italy

Facility Name

Research Site

City

Legnago VR

ZIP/Postal Code

37045

Country

Italy

Facility Name

Research Site

City

Lugo RA

ZIP/Postal Code

48022

Country

Italy

Facility Name

Research Site

City

Meldola FC

ZIP/Postal Code

47014

Country

Italy

Facility Name

Research Site

City

Messina

ZIP/Postal Code

98125

Country

Italy

Facility Name

Research Site

City

Milano

ZIP/Postal Code

20142

Country

Italy

Facility Name

Research Site

City

Napoli

ZIP/Postal Code

80131

Country

Italy

Facility Name

Research Site

City

Ravenna

ZIP/Postal Code

48100

Country

Italy

Facility Name

Research Site

City

Reggio Calabria

ZIP/Postal Code

89124

Country

Italy

Facility Name

Research Site

City

San Giovanni Rotondo FG

ZIP/Postal Code

71013

Country

Italy

Facility Name

Research Site

City

Nagoya-shi

State/Province

Aichi

ZIP/Postal Code

460-0001

Country

Japan

Facility Name

Research Site

City

Fukui-Shi

State/Province

Fukui

ZIP/Postal Code

910-8526

Country

Japan

Facility Name

Research Site

City

Chikushino-shi

State/Province

Fukuoka

ZIP/Postal Code

818-8516

Country

Japan

Facility Name

Research Site

City

Kurume-shi

State/Province

Fukuoka

ZIP/Postal Code

830-0011

Country

Japan

Facility Name

Research Site

City

Amagasaki-shi

State/Province

Hyogo

ZIP/Postal Code

660-8550

Country

Japan

Facility Name

Research Site

City

Kobe-shi

State/Province

Hyogo

ZIP/Postal Code

650-0017

Country

Japan

Facility Name

Research Site

City

Kobe

State/Province

Hyogo

ZIP/Postal Code

650-0047

Country

Japan

Facility Name

Research Site

City

Nishinomiya-shi

State/Province

Hyogo

ZIP/Postal Code

663-8501

Country

Japan

Facility Name

Research Site

City

Kanazawa

State/Province

Ishikawa

ZIP/Postal Code

920-8641

Country

Japan

Facility Name

Research Site

City

Sagamihara-shi

State/Province

Kanagawa

ZIP/Postal Code

252-0375

Country

Japan

Facility Name

Research Site

City

Okayama-shi

State/Province

Okayama

ZIP/Postal Code

700-8607

Country

Japan

Facility Name

Research Site

City

Osaka-shi

State/Province

Osaka

ZIP/Postal Code

541-8567

Country

Japan

Facility Name

Research Site

City

Osaka-shi

State/Province

Osaka

ZIP/Postal Code

545-8586

Country

Japan

Facility Name

Research Site

City

Bunkyo-ku

State/Province

Tokyo

ZIP/Postal Code

113-8603

Country

Japan

Facility Name

Research Site

City

Shinjuku-ku

State/Province

Tokyo

ZIP/Postal Code

160-0023

Country

Japan

Facility Name

Research Site

City

Yonago-shi

State/Province

Tottori

ZIP/Postal Code

683-8504

Country

Japan

Facility Name

Research Site

City

Kyoto

ZIP/Postal Code

615-8256

Country

Japan

Facility Name

Research Site

City

Gwangju

ZIP/Postal Code

519-763

Country

Korea, Republic of

Facility Name

Research Site

City

Seongnam-si, Gyeonggido

ZIP/Postal Code

463-707

Country

Korea, Republic of

Facility Name

Research Site

City

Seoul

ZIP/Postal Code

136-705

Country

Korea, Republic of

Facility Name

Research Site

City

Esch-Sur-Alzette

ZIP/Postal Code

4005

Country

Luxembourg

Facility Name

Research Site

City

Luxembourg

ZIP/Postal Code

1210

Country

Luxembourg

Facility Name

Research Site

City

Kota Bharu

State/Province

Kelantan

ZIP/Postal Code

16150

Country

Malaysia

Facility Name

Research Site

City

Kuantan

State/Province

Pahang

ZIP/Postal Code

25100

Country

Malaysia

Facility Name

Research Site

City

Georgetown

State/Province

Pinang

ZIP/Postal Code

10050

Country

Malaysia

Facility Name

Research Site

City

Kota Kinabalu

State/Province

Sabah

ZIP/Postal Code

88996

Country

Malaysia

Facility Name

Research Site

City

Kuala Lumpur

State/Province

Wilayah Persekutuan

ZIP/Postal Code

56000

Country

Malaysia

Facility Name

Research Site

City

Kuala Lumpur

State/Province

Wilayah Persekutuan

ZIP/Postal Code

59100

Country

Malaysia

Facility Name

Research Site

City

Saltillo

State/Province

Coahuila

ZIP/Postal Code

25000

Country

Mexico

Facility Name

Research Site

City

Mexico City

State/Province

Distrito Federal

ZIP/Postal Code

06720

Country

Mexico

Facility Name

Research Site

City

Mexico City

State/Province

Distrito Federal

ZIP/Postal Code

14080

Country

Mexico

Facility Name

Research Site

City

Mexico City

State/Province

Distrito Federal

ZIP/Postal Code

14140

Country

Mexico

Facility Name

Research Site

City

Mexico

State/Province

Distrito Federal

ZIP/Postal Code

06100

Country

Mexico

Facility Name

Research Site

City

Mexico

State/Province

Distrito Federal

ZIP/Postal Code

06720

Country

Mexico

Facility Name

Research Site

City

Mexico

State/Province

Distrito Federal

ZIP/Postal Code

07300

Country

Mexico

Facility Name

Research Site

City

Leon

State/Province

Guanajuato

ZIP/Postal Code

37000

Country

Mexico

Facility Name

Research Site

City

Guadalajara

State/Province

Jalisco

ZIP/Postal Code

44340

Country

Mexico

Facility Name

Research Site

City

Zapopan

State/Province

Jalisco

ZIP/Postal Code

45200

Country

Mexico

Facility Name

Research Site

City

Monterrey

State/Province

Nuevo León

ZIP/Postal Code

64710

Country

Mexico

Facility Name

Research Site

City

Queretaro

State/Province

Querétaro

ZIP/Postal Code

76090

Country

Mexico

Facility Name

Research Site

City

San Luis Potosi

State/Province

San Luis Potosí

ZIP/Postal Code

78216

Country

Mexico

Facility Name

Research Site

City

Merida

State/Province

Yucatán

ZIP/Postal Code

97000

Country

Mexico

Facility Name

Research Site

City

Chihuahua

ZIP/Postal Code

31217

Country

Mexico

Facility Name

Research Site

City

Colima

ZIP/Postal Code

28030

Country

Mexico

Facility Name

Research Site

City

Oaxaca

ZIP/Postal Code

68000

Country

Mexico

Facility Name

Research Site

City

Puebla

ZIP/Postal Code

72270

Country

Mexico

Facility Name

Research Site

City

Breda

ZIP/Postal Code

4818 CK

Country

Netherlands

Facility Name

Research Site

City

Eindhoven

ZIP/Postal Code

5623 EJ

Country

Netherlands

Facility Name

Research Site

City

Rotterdam

ZIP/Postal Code

3015 CE

Country

Netherlands

Facility Name

Research Site

City

Tilburg

ZIP/Postal Code

5022 GC

Country

Netherlands

Facility Name

Research Site

City

Davao City

State/Province

Davao

ZIP/Postal Code

8000

Country

Philippines

Facility Name

Research Site

City

Krakow

ZIP/Postal Code

31-501

Country

Poland

Facility Name

Research Site

City

Olsztyn

ZIP/Postal Code

10-228

Country

Poland

Facility Name

Research Site

City

Olsztyn

ZIP/Postal Code

10-357

Country

Poland

Facility Name

Research Site

City

Rzeszow

ZIP/Postal Code

35-055

Country

Poland

Facility Name

Research Site

City

San Juan

ZIP/Postal Code

00910

Country

Puerto Rico

Facility Name

Research Site

City

San Juan

ZIP/Postal Code

00927

Country

Puerto Rico

Facility Name

Research Site

City

Sibiu

ZIP/Postal Code

550245

Country

Romania

Facility Name

Research Site

City

Arkhangelsk

ZIP/Postal Code

163045

Country

Russian Federation

Facility Name

Research Site

City

Barnaul

ZIP/Postal Code

656049

Country

Russian Federation

Facility Name

Research Site

City

Belgorod

ZIP/Postal Code

308010

Country

Russian Federation

Facility Name

Research Site

City

Ivanovo

ZIP/Postal Code

153013

Country

Russian Federation

Facility Name

Research Site

City

Kirov

ZIP/Postal Code

610021

Country

Russian Federation

Facility Name

Research Site

City

Krasnodar

ZIP/Postal Code

350000

Country

Russian Federation

Facility Name

Research Site

City

Kursk

ZIP/Postal Code

305035

Country

Russian Federation

Facility Name

Research Site

City

Lipetsk

ZIP/Postal Code

398005

Country

Russian Federation

Facility Name

Research Site

City

Moscow

ZIP/Postal Code

115478

Country

Russian Federation

Facility Name

Research Site

City

Nizhniy Novgorod

ZIP/Postal Code

603081

Country

Russian Federation

Facility Name

Research Site

City

Novosibirsk

ZIP/Postal Code

630047

Country

Russian Federation

Facility Name

Research Site

City

Obninsk

ZIP/Postal Code

249036

Country

Russian Federation

Facility Name

Research Site

City

Omsk

ZIP/Postal Code

644013

Country

Russian Federation

Facility Name

Research Site

City

Orenburg

ZIP/Postal Code

460021

Country

Russian Federation

Facility Name

Research Site

City

Penza

ZIP/Postal Code

440071

Country

Russian Federation

Facility Name

Research Site

City

Pyatigorsk

ZIP/Postal Code

357502

Country

Russian Federation

Facility Name

Research Site

City

Saint-Petersburg

ZIP/Postal Code

197101

Country

Russian Federation

Facility Name

Research Site

City

Samara

ZIP/Postal Code

443031

Country

Russian Federation

Facility Name

Research Site

City

Saratov

ZIP/Postal Code

410004

Country

Russian Federation

Facility Name

Research Site

City

Stavropol

ZIP/Postal Code

355047

Country

Russian Federation

Facility Name

Research Site

City

Tula

ZIP/Postal Code

300040

Country

Russian Federation

Facility Name

Research Site

City

Tver

ZIP/Postal Code

170008

Country

Russian Federation

Facility Name

Research Site

City

Ufa

ZIP/Postal Code

450054

Country

Russian Federation

Facility Name

Research Site

City

Ulyanovsk

ZIP/Postal Code

432063

Country

Russian Federation

Facility Name

Research Site

City

Voronezh

ZIP/Postal Code

394000

Country

Russian Federation

Facility Name

Research Site

City

Yaroslavl

ZIP/Postal Code

150040

Country

Russian Federation

Facility Name

Research Site

City

Belgrade

ZIP/Postal Code

11129

Country

Serbia

Facility Name

Research Site

City

Gornji Matejevac

ZIP/Postal Code

18204

Country

Serbia

Facility Name

Research Site

City

Kragujevac

ZIP/Postal Code

34000

Country

Serbia

Facility Name

Research Site

City

Sremska Kamenica

ZIP/Postal Code

21204

Country

Serbia

Facility Name

Research Site

City

Golnik

ZIP/Postal Code

4204

Country

Slovenia

Facility Name

Research Site

City

Pohorje

ZIP/Postal Code

2208

Country

Slovenia

Facility Name

Research Site

City

Umhlanga

State/Province

KwaZulu-Natal

ZIP/Postal Code

4320

Country

South Africa

Facility Name

Research Site

City

Bloemfontein

ZIP/Postal Code

9301

Country

South Africa

Facility Name

Research Site

City

Johannesburg

ZIP/Postal Code

1501

Country

South Africa

Facility Name

Research Site

City

Overport

ZIP/Postal Code

4091

Country

South Africa

Facility Name

Research Site

City

Polokwane

ZIP/Postal Code

0699

Country

South Africa

Facility Name

Research Site

City

Granada

State/Province

Andalucía

ZIP/Postal Code

18014

Country

Spain

Facility Name

Research Site

City

Las Palmas de Gran Canaria

State/Province

Canarias

ZIP/Postal Code

35016

Country

Spain

Facility Name

Research Site

City

Barcelona

State/Province

Cataluña

ZIP/Postal Code

08036

Country

Spain

Facility Name

Research Site

City

Alicante

State/Province

Comunidad Valenciana

ZIP/Postal Code

03010

Country

Spain

Facility Name

Research Site

City

Benidorm

State/Province

Comunidad Valenciana

ZIP/Postal Code

03501

Country

Spain

Facility Name

Research Site

City

Valencia

State/Province

Comunidad Valenciana

ZIP/Postal Code

46017

Country

Spain

Facility Name

Research Site

City

Pontevedra

State/Province

Galicia

ZIP/Postal Code

36001

Country

Spain

Facility Name

Research Site

City

Aarau

ZIP/Postal Code

5000

Country

Switzerland

Facility Name

Research Site

City

Aarau

ZIP/Postal Code

5001

Country

Switzerland

Facility Name

Research Site

City

Chur

ZIP/Postal Code

7000

Country

Switzerland

Facility Name

Research Site

City

Sursee

ZIP/Postal Code

6210

Country

Switzerland

Facility Name

Research Site

City

Zurich

ZIP/Postal Code

8063

Country

Switzerland

Facility Name

Research Site

City

Kaohsiung

ZIP/Postal Code

81362

Country

Taiwan

Facility Name

Research Site

City

Taichung

ZIP/Postal Code

40705

Country

Taiwan

Facility Name

Research Site

City

Kirovograd

ZIP/Postal Code

25011

Country

Ukraine

Facility Name

Research Site

City

Bebington

ZIP/Postal Code

CH63 4JY

Country

United Kingdom

Facility Name

Research Site

City

Dorechester

ZIP/Postal Code

DT1 2JY

Country

United Kingdom

Facility Name

Research Site

City

Dorset

ZIP/Postal Code

BH15 2JB

Country

United Kingdom

Facility Name

Research Site

City

Liverpool

ZIP/Postal Code

L14 3PE

Country

United Kingdom

Facility Name

Research Site

City

Manchester

ZIP/Postal Code

M20 4BX

Country

United Kingdom

12. IPD Sharing Statement

Citations:

PubMed Identifier

31629060

Citation

Gascon P, Nagarkar R, Smakal M, Syrigos KN, Barrios CH, Sanchez JC, Zhang L, Henry DH, Gordon D, Hirsh V, Kubota K, Orlov S, Thomas G, Steinmetz T, Kang JH, Tomita DK, Fleishman AN, Park JK, De Oliveira Brandao C. A Randomized, Double-Blind, Placebo-Controlled, Phase III Noninferiority Study of the Long-Term Safety and Efficacy of Darbepoetin Alfa for Chemotherapy-Induced Anemia in Patients With Advanced NSCLC. J Thorac Oncol. 2020 Feb;15(2):190-202. doi: 10.1016/j.jtho.2019.10.005. Epub 2019 Oct 16.

Results Reference

background

Links:

URL

http://www.amgentrials.com

Description

AmgenTrials clinical trials website

Learn more about this trial

Anemia Treatment for Advanced Non-Small Cell Lung Cancer (NSCLC) Patients Receiving Chemotherapy

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Anemia Treatment for Advanced Non-Small Cell Lung Cancer (NSCLC) Patients Receiving Chemotherapy

Non-Small Cell Lung Cancer, Anemia, Cancer

About this trial

Eligibility Criteria

Sites / Locations

Arms of the Study

Arm 1

Arm 2

Outcomes

Primary Outcome Measures

Secondary Outcome Measures

Full Information

1. Study Identification

2. Study Status

3. Sponsor/Collaborators

4. Oversight

5. Study Description

6. Conditions and Keywords

7. Study Design

8. Arms, Groups, and Interventions

10. Eligibility

12. IPD Sharing Statement

Learn more about this trial