ART Readiness in HIV-infected Pregnant Women
Human Immunodeficiency Virus
About this trial
This is an interventional health services research trial for Human Immunodeficiency Virus
Eligibility Criteria
The criteria vary by study phase as follows:
Phase 1
Inclusion Criteria:
- HIV-infected pregnant women not yet on ART OR
- HIV-infected pregnant or postnatal women on ART OR
- Partners of women who were recently or are currently pregnant
Exclusion Criteria:
- Less than 18 years old
- Known history of mental illness
Phase 2
Inclusion Criteria:
- HIV-infected pregnant or postnatal women on ART who piloted tested the readiness assessment tool OR
- Health care workers involved in provision of PMTCT and/or ART services at health facility who have pilot tested the readiness assessment tool
Phase 3
Inclusion Criteria:
- Pregnant
- HIV-infected
- Never previously initiated or was on ART for her own health
- Able to provide informed consent
- Willing to undergo all study tests and procedures and be followed until 6 months post-partum
Exclusion criteria:
- Less than 18 years old
- Known intrauterine fetal demise
- Known history of mental illness
- Does not intend to receive antenatal care, labour and delivery care, and postnatal care at the government health facilities of Lusaka District
Sites / Locations
- Centre for Infectious Disease Research in Zambia
Arms of the Study
Arm 1
Arm 2
Other
Experimental
Standard of Care
Enhanced adherence package
The MOH-recommended approach is opt out HIV testing in pregnancy followed by immediate initiation of ART for HIV-infected pregnant women. ART initiation is accompanied with counseling geared to educate and prepare women to take up and be retained on ART lifelong. Women who do not return for clinical or drug refill visits are traced by phone or in person.
The enhanced adherence package will be designed on the basis of the results of formative research. The intervention will support women who are eligible for ART under Option B+.