Artificial Intelligence for Leaving in Situ Colorectal Polyps.
Colonic Neoplasms
About this trial
This is an interventional prevention trial for Colonic Neoplasms
Eligibility Criteria
Inclusion criteria:
- All >18 years-old patients undergoing elective colonoscopy
Exclusion criteria:
- patients with personal history of colorectal cancer (CRC), or Inflammatory Bowel Disease (IBD).
- Patients affected with Lynch syndrome or Familiar Adenomatous Polyposis.
- patients with inadequate bowel preparation (defined as Boston Bowel Preparation Scale <2 in any colonic segment).
- patients with previous colonic resection.
- patients on antithrombotic therapy, precluding polyp resection.
- patients who were not able or refused to give informed written consent.
Sites / Locations
- Ospedale Dei CastelliRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Leave-In-Situ Arm
Standard arm
standard, high-definition colonoscopy with the use of Medtronic GI Genius module including both CADe and CADx. Polyps will be left in situ if diminutive (≤5 mm) in size, located in the rectum or sigma and optically diagnosed by the endoscopist using the system to be hyperplastic with high confidence, otherwise resected and sent to pathology.
standard, high-definition colonoscopy with the use of Medtronic GI Genius module including both CADe and CADx. All detected polyps regardless of size and optical diagnosis will be resected and sent to pathology.