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ASPIrin in Reducing Events in Dialysis ( ASPIRED )

Primary Purpose

CKD (Chronic Kidney Disease) Stage 5D

Status
Recruiting
Phase
Phase 4
Locations
China
Study Type
Interventional
Intervention
Aspirin 100 mg Oral Tablet
Sponsored by
Guangdong Provincial People's Hospital
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional treatment trial for CKD (Chronic Kidney Disease) Stage 5D focused on measuring Aspirin, Dialysis, End Stage Kidney Disease

Eligibility Criteria

18 Years - undefined (Adult, Older Adult)All SexesDoes not accept healthy volunteers

Inclusion Criteria:

  • Adult patients who are entered into the Chinese PD and HD dialysis registry
  • Expected requirement for ongoing maintenance dialysis
  • Willing and able to provide informed consent

Exclusion Criteria:

  • Requirement of antiplatelet agent or oral anticoagulation, in the view of the treating physician
  • Contraindication to aspirin
  • Dialysis requirement due to acute kidney injure I with the expectation of kidney function recovery
  • History of haemorrhagic stroke or intracranial bleed within the past 12 months
  • Coagulopathy from any cause

Sites / Locations

  • The First Affiliated Hospital of Fujian Medical University
  • The First Hospital of Lanzhou UniversityRecruiting
  • Chaozhou Center Hospital
  • Dongguan Donghua Hospital
  • Dongguan People's Hospital
  • The Second People Hospital of Foshan Nanhai
  • Foshan Nanhai District People's HospitalRecruiting
  • Foshan No.1 people's hospitalRecruiting
  • Foshan Sanshui District People's Hospital
  • Foshan Second People's HospitalRecruiting
  • Shunde People's Hospital
  • The Third Affiliated Hospital of Southern Medical University
  • The first Affiliated Hospital of Guangzhou Medical University
  • Sun Yat-sen Memorial Hospital
  • Guangzhou Redcross Hospital
  • The first Affiliated Hospital of Jinan University
  • Guangdong Agricultural Reclamation Central HospitalRecruiting
  • Guangdong Provincial Peoples HospitalRecruiting
  • Guangzhou First People's HospitalRecruiting
  • Hua Du District People's Hospital of GuangzhouRecruiting
  • Panyu District people's hospital of GuangzhouRecruiting
  • The Sixth Affiliated Hospital of Sun yat-sen UniversityRecruiting
  • The Third Affiliated Hospital of Sun Yat-sen UniversityRecruiting
  • The First Affiliated Hospital of Sun Yat-sen UniversityRecruiting
  • Heyuan People's HospitalRecruiting
  • Huizhou First People Hospital
  • Jiangmen Center hospitalRecruiting
  • Kaiping Center HospitalRecruiting
  • Lianjiang People's HospitalRecruiting
  • Maoming People's Hospital
  • Meizhou People's HospitalRecruiting
  • The Third Affiliated Hospital of Sun Yat-sen University Yuedong Hospital
  • Nanxiong People Hospital
  • Qingyuan People's Hospital
  • Fogang People Hospital
  • The first Affiliated Hospital of Shantou Medical University
  • Shantou Chaonan Minsheng Hospital
  • Shanwei People's Hospital
  • Wengyuan People Hospital
  • The First People's Hospital of ShaoguanRecruiting
  • The Seventh Affiliated Hospital of Sun Yat-sen
  • Shenzhen Baoan People's HospitalRecruiting
  • Shenzhen No.2 people's hospitalRecruiting
  • Yangjiang People's Hospital
  • Yunfu People's Hospital
  • The Affiliated Hospital of Guangdong Medical University
  • Central People's Hospital of Zhanjiang
  • Zhaoqing first people's hospitalRecruiting
  • Zhongshan City People's HospitalRecruiting
  • Zhongshan Traditional Chinese Hospital
  • The fifth affiliated hospital of sun yat-sen universityRecruiting
  • The Affiliated Hospital of Youjiang Ethnic Medicine CollegeRecruiting
  • The first affiliated hospital of Guangxi Medical UniversityRecruiting
  • Anshun People Hospital
  • Guizhou Province Peple's Hospital
  • Guizhou Provincial People's Hospital
  • Hainan Provincial People's HospitalRecruiting
  • Xinyang Central HospitalRecruiting
  • The Central Hospital of WuhanRecruiting
  • The Union Hospital Affiliated to Tongji Medical College of Huazhong University of Science and TechnologyRecruiting
  • Tongji Hospital, Tongji Medical College of Huazhong Science and Technology UniversityRecruiting
  • Wuhan First HospitalRecruiting
  • Wuhan No.1 People's HospitalRecruiting
  • Yichang central people's hospital
  • Zhongnan Hospital of Wuhan University
  • Hunan Provincial People's HospitalRecruiting
  • The third Xiangya Hospital of Central South UniversityRecruiting
  • Xiangya Hospital Central South UniversityRecruiting
  • The Affiliated Hospital of Inner Mongolia Medical University
  • Ganzhou Municiple HospitalRecruiting
  • Ganzhou People's HospitalRecruiting
  • Jiujiang No.1people's Hospital
  • Jiangxi Province Peple's HospitalRecruiting
  • The First Affiliated Hospital of Nanchang UniversityRecruiting
  • General Hospital of Ningxia Medical UniversityRecruiting
  • The Affiliated Hospital of Qingdao University
  • The First Affiliated Hospital of Air Force Military Medical University
  • Sichuan Province People's HospitalRecruiting
  • The First People's Hospital of Kashi PrefectureRecruiting
  • The First Affiliated Hospital of Shihezi University Medical CollegeRecruiting
  • The First Affiliated Hospital of Xinjiang Medical University
  • The People's hospital of Xinjiang Uygur Autonomous Region
  • Fengqing People's Hospital of Yunnan ProvinceRecruiting
  • The First Affiliated Hospital, Zhejiang University

Arms of the Study

Arm 1

Arm 2

Arm Type

Active Comparator

Placebo Comparator

Arm Label

Aspirin

Matching Placebo

Arm Description

Aspirin tablet 100mg daily

Placebo tablet 1 pill daily

Outcomes

Primary Outcome Measures

Number of Participants with composite of major cardiovascular events (3-point MACE)
A composite of cardiovascular death, myocardial infarction, or ischemic stroke.

Secondary Outcome Measures

Number of Participants with composite of the primary outcome plus all-cause death
A composite of cardiovascular death, myocardial infarction, ischemic stroke or death.
Number of Participants with composite of major cardiovascular events, hospitalised unstable angina (UA) and hospitalised transient ischaemic attack (TIA)
Number of Participants with cardiovascular death
Myocardial infarction
Number of Participants with stroke
Number of Participants with all-cause death
Death for any reason.
Number of Participants with coronary revascularization
Number of Participants with fistula or graft thrombosis
Number of Participants with haemorrhagic stroke
Number of Participants with ischemic events
Defined as a composite of myocardial infarction (MI), coronary death, ischemic stroke, or any revascularization procedure (i.e, exclusion of noncoronary cardiac deaths and strokes confirmed to be haemorrhagic).

Full Information

First Posted
April 23, 2020
Last Updated
June 8, 2023
Sponsor
Guangdong Provincial People's Hospital
Collaborators
George Clinical Pty Ltd
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1. Study Identification

Unique Protocol Identification Number
NCT04381143
Brief Title
ASPIrin in Reducing Events in Dialysis ( ASPIRED )
Official Title
ASPIrin in Reducing Events in Dialysis
Study Type
Interventional

2. Study Status

Record Verification Date
June 2023
Overall Recruitment Status
Recruiting
Study Start Date
July 30, 2020 (Actual)
Primary Completion Date
July 2025 (Anticipated)
Study Completion Date
July 2026 (Anticipated)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Sponsor
Name of the Sponsor
Guangdong Provincial People's Hospital
Collaborators
George Clinical Pty Ltd

4. Oversight

Studies a U.S. FDA-regulated Drug Product
No
Studies a U.S. FDA-regulated Device Product
No
Data Monitoring Committee
Yes

5. Study Description

Brief Summary
People with kidney failure requiring dialysis have a much higher risk of developing cardiovascular (CV) disease compared with the general population. A cardiac cause accounts for 58% of all deaths in patients with end stage kidney disease (ESKD). At the same time, this population has increased risks of clotting as well as bleeding episodes. While aspirin is known to reduce cardiovascular complications in the general population, evidence to support the use of aspirin in people with ESKD receiving dialysis therapy is currently lacking. The ASPIrin to Reduce Event in Dialysis (ASPIRED) trial will test whether aspirin use in dialysis patients safely improves outcomes compared with no aspirin use.
Detailed Description
ASPIRED is an investigator-initiated, multi-center, double-blind, parallel group, event-driven, pragmatic, registry-based randomized controlled trial that will define the value of low dose aspirin (100 mg daily) on cardiovascular events in people with ESKD receiving dialysis. The study will be conducted using the existing platform of the Chinese peritoneal dialysis (PD) and hemodialysis (HD) Dialysis Registry to screen, recruit and to collect study data as part of patient's routine clinical care during dialysis to improve efficiency and to minimize cost of a clinical trial. ASPIRED is an event driven trial with an anticipated duration of approximately 5 years. Randomization will be performed using a web-based system via a pass word protected encrypted website interface. The study procedure utilizes routine six-monthly clinic visits for study follow-up to increase efficiency and minimize the burden on participants. The analysis will be based on intention-to-treat principles. An independent Data Safety and Monitoring Board (DSMB) will established to monitor the study for safety and efficacy.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
CKD (Chronic Kidney Disease) Stage 5D
Keywords
Aspirin, Dialysis, End Stage Kidney Disease

7. Study Design

Primary Purpose
Treatment
Study Phase
Phase 4
Interventional Study Model
Parallel Assignment
Model Description
Pragmatic designs
Masking
ParticipantCare ProviderInvestigatorOutcomes Assessor
Allocation
Randomized
Enrollment
9000 (Anticipated)

8. Arms, Groups, and Interventions

Arm Title
Aspirin
Arm Type
Active Comparator
Arm Description
Aspirin tablet 100mg daily
Arm Title
Matching Placebo
Arm Type
Placebo Comparator
Arm Description
Placebo tablet 1 pill daily
Intervention Type
Drug
Intervention Name(s)
Aspirin 100 mg Oral Tablet
Intervention Description
Aspirin 100 mg tablets daily
Primary Outcome Measure Information:
Title
Number of Participants with composite of major cardiovascular events (3-point MACE)
Description
A composite of cardiovascular death, myocardial infarction, or ischemic stroke.
Time Frame
From trial initiation to any event first occurrence, up to 5 years.
Secondary Outcome Measure Information:
Title
Number of Participants with composite of the primary outcome plus all-cause death
Description
A composite of cardiovascular death, myocardial infarction, ischemic stroke or death.
Time Frame
From trial initiation to any event first occurrence, up to 5 years.
Title
Number of Participants with composite of major cardiovascular events, hospitalised unstable angina (UA) and hospitalised transient ischaemic attack (TIA)
Time Frame
From trial initiation to any event first occurrence, up to 5 years.
Title
Number of Participants with cardiovascular death
Time Frame
From trial initiation to any event first occurrence, up to 5 years.
Title
Myocardial infarction
Time Frame
From trial initiation to any event first occurrence, up to 5 years.
Title
Number of Participants with stroke
Time Frame
From trial initiation to any event first occurrence, up to 5 years.
Title
Number of Participants with all-cause death
Description
Death for any reason.
Time Frame
From trial initiation to any event first occurrence, up to 5 years.
Title
Number of Participants with coronary revascularization
Time Frame
From trial initiation to any event occurrence, up to 5 years.
Title
Number of Participants with fistula or graft thrombosis
Time Frame
From trial initiation to any event occurrence, up to 5 years.
Title
Number of Participants with haemorrhagic stroke
Time Frame
From trial initiation to any event occurrence, up to 5 years.
Title
Number of Participants with ischemic events
Description
Defined as a composite of myocardial infarction (MI), coronary death, ischemic stroke, or any revascularization procedure (i.e, exclusion of noncoronary cardiac deaths and strokes confirmed to be haemorrhagic).
Time Frame
From trial initiation to any event occurrence, up to 5 years.
Other Pre-specified Outcome Measures:
Title
Major bleeding
Description
Major bleeding is defined based on modified International Society on Thrombosis and Haemostasis (ISTH) definition, including fatal bleeding, and/or symptomatic bleeding in a critical area or organ, such as intracranial, intra-spinal, intra-ocular, retro-peritoneal, intra-articular or pericardial, or intramuscular with compartment syndrome, or bleeding into a surgical site requiring re-operation, and/or bleeding leading to hospitalization.
Time Frame
From trial initiation to any event first occurrence, up to 5 years.

10. Eligibility

Sex
All
Minimum Age & Unit of Time
18 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria: Adult patients who are entered into the Chinese PD and HD dialysis registry Expected requirement for ongoing maintenance dialysis Willing and able to provide informed consent Exclusion Criteria: Requirement of antiplatelet agent or oral anticoagulation, in the view of the treating physician Contraindication to aspirin Dialysis requirement due to acute kidney injure I with the expectation of kidney function recovery History of haemorrhagic stroke or intracranial bleed within the past 12 months Coagulopathy from any cause
Central Contact Person:
First Name & Middle Initial & Last Name or Official Title & Degree
Xueqing Yu
Phone
+86-20-83827812
Email
yuxueqing@gdph.org.cn
First Name & Middle Initial & Last Name or Official Title & Degree
Li Fan
Phone
+86-20-87755766-8174
Email
fanli5@mail.sysu.edu.cn
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Xueqing Yu
Organizational Affiliation
Guangdong Provincial People's Hospital
Official's Role
Study Chair
First Name & Middle Initial & Last Name & Degree
Vlado Perkovic
Organizational Affiliation
The George Institute
Official's Role
Study Chair
First Name & Middle Initial & Last Name & Degree
Muh Geot Wong
Organizational Affiliation
The George Institute
Official's Role
Study Director
First Name & Middle Initial & Last Name & Degree
Wei Chen
Organizational Affiliation
First Affiliated Hospital, Sun Yat-Sen University
Official's Role
Study Director
First Name & Middle Initial & Last Name & Degree
Li Fan
Organizational Affiliation
First Affiliated Hospital, Sun Yat-Sen University
Official's Role
Study Director
First Name & Middle Initial & Last Name & Degree
Zhiming Ye
Organizational Affiliation
Guangdong Provincial People's Hospital
Official's Role
Study Director
Facility Information:
Facility Name
The First Affiliated Hospital of Fujian Medical University
City
Fuzhou
State/Province
Fujian
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jianxin Wan
Facility Name
The First Hospital of Lanzhou University
City
Lanzhou
State/Province
Gansu
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Tianxi Liu
Facility Name
Chaozhou Center Hospital
City
Chaozhou
State/Province
Guangdong
Country
China
Individual Site Status
Withdrawn
Facility Name
Dongguan Donghua Hospital
City
Dongguan
State/Province
Guangdong
ZIP/Postal Code
523413
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Xiaoyan Su
First Name & Middle Initial & Last Name & Degree
Xiaoyan Su
Facility Name
Dongguan People's Hospital
City
Dongguan
State/Province
Guangdong
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Guohui Liu
First Name & Middle Initial & Last Name & Degree
Yi Li
Facility Name
The Second People Hospital of Foshan Nanhai
City
Foshan
State/Province
Guangdong
ZIP/Postal Code
528251
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Xia Jiang
First Name & Middle Initial & Last Name & Degree
Xia Jiang
Facility Name
Foshan Nanhai District People's Hospital
City
Foshan
State/Province
Guangdong
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Fuzhang Luo
Facility Name
Foshan No.1 people's hospital
City
Foshan
State/Province
Guangdong
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yaozhong Kong
Facility Name
Foshan Sanshui District People's Hospital
City
Foshan
State/Province
Guangdong
Country
China
Individual Site Status
Withdrawn
Facility Name
Foshan Second People's Hospital
City
Foshan
State/Province
Guangdong
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Bo Zhang
Facility Name
Shunde People's Hospital
City
Foshan
State/Province
Guangdong
Country
China
Individual Site Status
Withdrawn
Facility Name
The Third Affiliated Hospital of Southern Medical University
City
Guangzhou
State/Province
Guangdong
ZIP/Postal Code
225200
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Ying Tang
First Name & Middle Initial & Last Name & Degree
Ying Tang
Facility Name
The first Affiliated Hospital of Guangzhou Medical University
City
Guangzhou
State/Province
Guangdong
ZIP/Postal Code
510120
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Huafeng Liu
First Name & Middle Initial & Last Name & Degree
Huafeng Liu
Facility Name
Sun Yat-sen Memorial Hospital
City
Guangzhou
State/Province
Guangdong
ZIP/Postal Code
510235
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Qiongqiong Yang
First Name & Middle Initial & Last Name & Degree
Qiongqiong Yang
Facility Name
Guangzhou Redcross Hospital
City
Guangzhou
State/Province
Guangdong
ZIP/Postal Code
510240
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yan Liu
First Name & Middle Initial & Last Name & Degree
Yan Liu
Facility Name
The first Affiliated Hospital of Jinan University
City
Guangzhou
State/Province
Guangdong
ZIP/Postal Code
510630
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Panna Liu
First Name & Middle Initial & Last Name & Degree
Panna Liu
Facility Name
Guangdong Agricultural Reclamation Central Hospital
City
Guangzhou
State/Province
Guangdong
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jiping Wang
Facility Name
Guangdong Provincial Peoples Hospital
City
Guangzhou
State/Province
Guangdong
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Xueqing Yu
First Name & Middle Initial & Last Name & Degree
Xueqing Yu
Facility Name
Guangzhou First People's Hospital
City
Guangzhou
State/Province
Guangdong
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Shuguang Qin
Facility Name
Hua Du District People's Hospital of Guangzhou
City
Guangzhou
State/Province
Guangdong
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yunfang Zhang
Facility Name
Panyu District people's hospital of Guangzhou
City
Guangzhou
State/Province
Guangdong
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Minyan Xie
Facility Name
The Sixth Affiliated Hospital of Sun yat-sen University
City
Guangzhou
State/Province
Guangdong
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Zongpei Jiang
Facility Name
The Third Affiliated Hospital of Sun Yat-sen University
City
Guangzhou
State/Province
Guangdong
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Hui Peng
Facility Name
The First Affiliated Hospital of Sun Yat-sen University
City
Guanzhou
State/Province
Guangdong
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Wei Chen
Facility Name
Heyuan People's Hospital
City
Heyuan
State/Province
Guangdong
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jianteng Xie
Facility Name
Huizhou First People Hospital
City
Huizhou
State/Province
Guangdong
ZIP/Postal Code
516001
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yanbo Teng
First Name & Middle Initial & Last Name & Degree
Yanbo Teng
Facility Name
Jiangmen Center hospital
City
Jiangmen
State/Province
Guangdong
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Qingdong Xu
Facility Name
Kaiping Center Hospital
City
Kaiping
State/Province
Guangdong
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Xiaojun Tan
Facility Name
Lianjiang People's Hospital
City
Lianjiang
State/Province
Guangdong
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Wei Chen
Facility Name
Maoming People's Hospital
City
Maoming
State/Province
Guangdong
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yeming Lu
Facility Name
Meizhou People's Hospital
City
Meizhou
State/Province
Guangdong
ZIP/Postal Code
514011
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Xinghua Zhu
First Name & Middle Initial & Last Name & Degree
Xinghua Zhu
Facility Name
The Third Affiliated Hospital of Sun Yat-sen University Yuedong Hospital
City
Meizhou
State/Province
Guangdong
ZIP/Postal Code
514799
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Zhibo Liao
First Name & Middle Initial & Last Name & Degree
Zhibo Liao
Facility Name
Nanxiong People Hospital
City
Nanxiong
State/Province
Guangdong
ZIP/Postal Code
512499
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Lingjun Zeng
First Name & Middle Initial & Last Name & Degree
Lingjun Zeng
Facility Name
Qingyuan People's Hospital
City
Qingyuan
State/Province
Guangdong
ZIP/Postal Code
511518
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Zhiqiang Xue
First Name & Middle Initial & Last Name & Degree
Zhiqiang Xue
Facility Name
Fogang People Hospital
City
Qingyuan
State/Province
Guangdong
ZIP/Postal Code
511600
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Youhe Li
First Name & Middle Initial & Last Name & Degree
Youhe Li
Facility Name
The first Affiliated Hospital of Shantou Medical University
City
Shantou
State/Province
Guangdong
ZIP/Postal Code
515041
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yanqiang Peng
First Name & Middle Initial & Last Name & Degree
Yanqiang Peng
Facility Name
Shantou Chaonan Minsheng Hospital
City
Shantou
State/Province
Guangdong
ZIP/Postal Code
515144
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yubin Xia
First Name & Middle Initial & Last Name & Degree
Yubin Xia
Facility Name
Shanwei People's Hospital
City
Shanwei
State/Province
Guangdong
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jinxiong Xu
Facility Name
Wengyuan People Hospital
City
Shaoguan
State/Province
Guangdong
ZIP/Postal Code
512600
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yaoli Huang
First Name & Middle Initial & Last Name & Degree
Yaoli Huang
Facility Name
The First People's Hospital of Shaoguan
City
Shaoguan
State/Province
Guangdong
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Bing Zhou
Facility Name
The Seventh Affiliated Hospital of Sun Yat-sen
City
Shenzhen
State/Province
Guangdong
ZIP/Postal Code
510275
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Zhihua Zheng
First Name & Middle Initial & Last Name & Degree
Zhihua Zheng
Facility Name
Shenzhen Baoan People's Hospital
City
Shenzhen
State/Province
Guangdong
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jihong Chen
Facility Name
Shenzhen No.2 people's hospital
City
Shenzhen
State/Province
Guangdong
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Qijun Wan
Facility Name
Yangjiang People's Hospital
City
Yangjiang
State/Province
Guangdong
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yong Su
Facility Name
Yunfu People's Hospital
City
Yunfu
State/Province
Guangdong
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Xinyuan Liao
Facility Name
The Affiliated Hospital of Guangdong Medical University
City
Zhanjiang
State/Province
Guangdong
ZIP/Postal Code
524000
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jie Xiao
First Name & Middle Initial & Last Name & Degree
Jie Xiao
Facility Name
Central People's Hospital of Zhanjiang
City
Zhanjiang
State/Province
Guangdong
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Lei Zeng
Facility Name
Zhaoqing first people's hospital
City
Zhaoqing
State/Province
Guangdong
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jinquan Wu
First Name & Middle Initial & Last Name & Degree
Jinquan Wu
Facility Name
Zhongshan City People's Hospital
City
Zhongshan
State/Province
Guangdong
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Qing Ye
First Name & Middle Initial & Last Name & Degree
Qing Ye
Facility Name
Zhongshan Traditional Chinese Hospital
City
Zhongshan
State/Province
Guangdong
Country
China
Individual Site Status
Withdrawn
Facility Name
The fifth affiliated hospital of sun yat-sen university
City
Zhuhai
State/Province
Guangdong
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Cheng Wang
Facility Name
The Affiliated Hospital of Youjiang Ethnic Medicine College
City
Baise
State/Province
Guangxi
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jie Wang
Facility Name
The first affiliated hospital of Guangxi Medical University
City
Nanning
State/Province
Guangxi
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Zhenhua Yang
Facility Name
Anshun People Hospital
City
Anshun
State/Province
Guizhou
ZIP/Postal Code
561099
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Xianfeng Cheng
First Name & Middle Initial & Last Name & Degree
Xianfeng Cheng
Facility Name
Guizhou Province Peple's Hospital
City
Guiyang
State/Province
Guizhou
Country
China
Individual Site Status
Withdrawn
Facility Name
Guizhou Provincial People's Hospital
City
Guiyang
State/Province
Guizhou
Country
China
Individual Site Status
Withdrawn
Facility Name
Hainan Provincial People's Hospital
City
Haikou
State/Province
Hainan
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jiali Wei
Facility Name
Xinyang Central Hospital
City
Xinyang
State/Province
Henan
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Bo Zhang
Facility Name
The Central Hospital of Wuhan
City
Wuhan
State/Province
Hubei
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Wenli Chen
Facility Name
The Union Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology
City
Wuhan
State/Province
Hubei
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Chun Zhang
Facility Name
Tongji Hospital, Tongji Medical College of Huazhong Science and Technology University
City
Wuhan
State/Province
Hubei
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Gang Xu
Facility Name
Wuhan First Hospital
City
Wuhan
State/Province
Hubei
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Fei Xiong
First Name & Middle Initial & Last Name & Degree
Yanmin Zhang
Facility Name
Wuhan No.1 People's Hospital
City
Wuhan
State/Province
Hubei
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Fei Xiong
Facility Name
Yichang central people's hospital
City
Wuhan
State/Province
Hubei
Country
China
Individual Site Status
Withdrawn
Facility Name
Zhongnan Hospital of Wuhan University
City
Wuhan
State/Province
Hubei
Country
China
Individual Site Status
Withdrawn
Facility Name
Hunan Provincial People's Hospital
City
Changsha
State/Province
Hunan
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yumei Liang
Facility Name
The third Xiangya Hospital of Central South University
City
Changsha
State/Province
Hunan
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Hao Zhang
Facility Name
Xiangya Hospital Central South University
City
Changsha
State/Province
Hunan
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Xiangcheng Xiao
Facility Name
The Affiliated Hospital of Inner Mongolia Medical University
City
Hohhot
State/Province
Inner Mongolia
Country
China
Individual Site Status
Withdrawn
Facility Name
Ganzhou Municiple Hospital
City
Ganzhou
State/Province
Jiangxi
ZIP/Postal Code
341000
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Zhuo Li
First Name & Middle Initial & Last Name & Degree
Zhuo Li
Facility Name
Ganzhou People's Hospital
City
Ganzhou
State/Province
Jiangxi
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Hongxia Peng
Facility Name
Jiujiang No.1people's Hospital
City
Jiujiang
State/Province
Jiangxi
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Xiaoran Feng
Facility Name
Jiangxi Province Peple's Hospital
City
Nanchang
State/Province
Jiangxi
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Aimin Zhong
Facility Name
The First Affiliated Hospital of Nanchang University
City
Nanchang
State/Province
Jiangxi
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Qinkai Chen
Facility Name
General Hospital of Ningxia Medical University
City
Yinchuan
State/Province
Ningxia
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Menghua Chen
Facility Name
The Affiliated Hospital of Qingdao University
City
Qingdao
State/Province
Shandong
Country
China
Individual Site Status
Withdrawn
Facility Name
The First Affiliated Hospital of Air Force Military Medical University
City
Xi'an
State/Province
Shanxi
Country
China
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Shiren Sun
Facility Name
Sichuan Province People's Hospital
City
Chengdu
State/Province
Sichuan
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Li Wang
Facility Name
The First People's Hospital of Kashi Prefecture
City
Kashi
State/Province
Xinjiang
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jie Guo
Facility Name
The First Affiliated Hospital of Shihezi University Medical College
City
Shihezi
State/Province
Xinjiang
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Xiaoping Yang
Facility Name
The First Affiliated Hospital of Xinjiang Medical University
City
Ürümqi
State/Province
Xinjiang
Country
China
Individual Site Status
Withdrawn
Facility Name
The People's hospital of Xinjiang Uygur Autonomous Region
City
Ürümqi
State/Province
Xinjiang
Country
China
Individual Site Status
Withdrawn
Facility Name
Fengqing People's Hospital of Yunnan Province
City
Lincang
State/Province
Yunnan
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jinfeng Guo
Facility Name
The First Affiliated Hospital, Zhejiang University
City
Hangzhou
State/Province
Zhejiang
Country
China
Individual Site Status
Active, not recruiting

12. IPD Sharing Statement

Plan to Share IPD
Yes
IPD Sharing Plan Description
Deidentified study data that supports the results will be shared following publication. Any sub-study analysis and publication will have to be reviewed and approved by the Trial Steering Committee, local Ethics and Regulatory requirements.

Learn more about this trial

ASPIrin in Reducing Events in Dialysis ( ASPIRED )

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