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Assessment of Potential Interactions Between Methamphetamine and Bupropion - 1

Primary Purpose

Amphetamine-Related Disorders

Status
Unknown status
Phase
Phase 1
Locations
United States
Study Type
Interventional
Intervention
Bupropion
Sponsored by
National Institute on Drug Abuse (NIDA)
About
Eligibility
Locations
Outcomes
Full info

About this trial

This is an interventional diagnostic trial for Amphetamine-Related Disorders

Eligibility Criteria

18 Years - 45 Years (Adult)All SexesDoes not accept healthy volunteers

Inclusion Criteria: Please contact site director for more details. Exclusion Criteria: Please contact site director for more details.

Sites / Locations

  • UCLA Integrated Substance Abuse Program
  • University of Texas Health Science Center

Outcomes

Primary Outcome Measures

Psychological effects
BP, HR

Secondary Outcome Measures

Full Information

First Posted
June 18, 2002
Last Updated
January 10, 2017
Sponsor
National Institute on Drug Abuse (NIDA)
Collaborators
University of California, Los Angeles
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1. Study Identification

Unique Protocol Identification Number
NCT00040040
Brief Title
Assessment of Potential Interactions Between Methamphetamine and Bupropion - 1
Official Title
Double-Blind, Placebo-Controlled Assessment of Potential Interactions Between IV Methamphetamine and Oral Bupropion
Study Type
Interventional

2. Study Status

Record Verification Date
August 2003
Overall Recruitment Status
Unknown status
Study Start Date
June 2002 (undefined)
Primary Completion Date
undefined (undefined)
Study Completion Date
September 2003 (undefined)

3. Sponsor/Collaborators

Name of the Sponsor
National Institute on Drug Abuse (NIDA)
Collaborators
University of California, Los Angeles

4. Oversight

5. Study Description

Brief Summary
The purpose of this study is to assess potential interactions between intravenous (IV) methamphetamine and oral bupropion.
Detailed Description
This is a human laboratory clinical pharmacology study to assess potential interactions between IV methamphetamine challenge and treatment with oral sustained-release bupropion.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Amphetamine-Related Disorders

7. Study Design

Primary Purpose
Diagnostic
Study Phase
Phase 1
Masking
Double
Allocation
Randomized
Enrollment
20 (false)

8. Arms, Groups, and Interventions

Intervention Type
Drug
Intervention Name(s)
Bupropion
Primary Outcome Measure Information:
Title
Psychological effects
Title
BP, HR

10. Eligibility

Sex
All
Minimum Age & Unit of Time
18 Years
Maximum Age & Unit of Time
45 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria: Please contact site director for more details. Exclusion Criteria: Please contact site director for more details.
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Thomas Newton, M.D.
Organizational Affiliation
National Institute on Drug Abuse (NIDA)
Official's Role
Principal Investigator
Facility Information:
Facility Name
UCLA Integrated Substance Abuse Program
City
Los Angeles
State/Province
California
ZIP/Postal Code
90024
Country
United States
Facility Name
University of Texas Health Science Center
City
Houston
State/Province
Texas
ZIP/Postal Code
77225
Country
United States

12. IPD Sharing Statement

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Assessment of Potential Interactions Between Methamphetamine and Bupropion - 1

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