Barley Protein and CVD
Hypercholesterolemia, Cardiovascular Disease, Diet Therapy
About this trial
This is an interventional treatment trial for Hypercholesterolemia
Eligibility Criteria
Inclusion Criteria: men and postmenopausal women with mild- to-moderate hypercholesterolemia Body mass index >18 kg/m2 and < 36 kg/m2. treated by diet Alcohol intake < 14 drinks per week. Fasting plasma triglyceride (TG) concentration > 0.5 mmol/l and < 4.5 mmol/l. Fasting plasma LDL cholesterol concentration > 3.5 mmol/l at diagnosis. Exclusion Criteria: Child-bearing women Taking cholesterol lowering medications at the start of the study, unless their LDL-cholesterol levels are >3.5 mmol/L.However, with their physician's approval those who wish to join but are already taking cholesterol lowering medications with low LDL-cholesterol levels (e.g. <2.5 mmol/L) may join the study providing the medications are stopped for one month. Change the type or dose of their drug treatment during the study Patients judged as having a likelihood of being non-compliant with instructions for whatever reason Food allergies Evidence or history of diabetes, renal liver disease or gastrointestinal disease Recent (within 6 months)) major cardiovascular event (stroke or myocardial infarction) Secondary causes of hypercholesterolemia (or untreated hypothyroidism) Uncontrolled blood pressure Major disability or disorder such as liver disease, renal failure or cancer or with major surgery < 6 months prior to randomization
Sites / Locations
- St. Michael's Hospital