Benefits of an Intervention Combining Hypnosis and Self-care for Prostate Cancer Patients
Primary Purpose
Prostate Cancer
Status
Completed
Phase
Not Applicable
Locations
Study Type
Interventional
Intervention
Self-hypnosis + Self-care
Sponsored by

About this trial
This is an interventional supportive care trial for Prostate Cancer
Eligibility Criteria
Inclusion Criteria:
- 18-years-old,
- ability to read, write and speak French
- prostate cancer diagnosis
- treatment with surgery and/or radiotherapy.
Exclusion Criteria:
- metastases
- cancer recurrence at the moment of inclusion
- major cognitive or psychiatric disorder.
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Arm Type
Experimental
No Intervention
Arm Label
Intervention group : hypnosis + self-care
Control group : no intervention
Arm Description
Groupal intervention combining self-care techniques and self-hypnosis exercises
Control group receiving usual care but not the intervention
Outcomes
Primary Outcome Measures
Change in Fatigue
A sense of tiredness or exhaustion linked with cancer and its treatments, that is not alleviated by sleep. Measured by the European Organization for Research and Treatment of Cancer - Quality of Life Core Questionnaire-30 (EORTC-QLCQ30). One symptom-related scale (fatigue, score based on 3 items, varies from 0 to 100, 100 being the worst fatigue endured) and the global health status (2 items, score varies from 0 to 100, 100 being the best quality of life) are used in this study.
Change in emotional distress
Anxiety + Depression, measured with the Hospital Anxiety and Depression Scale (HADS). Scores range (total): 0-42 (0-14: absence of anxio-depressive disorder ; 15-42: presence of anxio-depressive disorder). Two scales: anxiety and depression. For each, scores range 0-21 (0-7: absence of anxious or depressive disorder; 8-10: possibility of an anxious or depressive disorder; 11-21: presence of anxious or depressive disorder).
Change in sleep difficulties
Sleep difficulties (difficulties to stay asleep, to fall asleep...) and their severity. Measured by the Insomnia Severity Index. One score is calculated and ranges from 0 to 22 (0-7: absence of insomnia; 8-14: subclinical insomnia; 15-21: moderate insomnia; 22-28: severe insomnia).
Secondary Outcome Measures
Full Information
NCT ID
NCT03423927
First Posted
January 30, 2018
Last Updated
February 5, 2018
Sponsor
University of Liege
Collaborators
Free University of Brussels
1. Study Identification
Unique Protocol Identification Number
NCT03423927
Brief Title
Benefits of an Intervention Combining Hypnosis and Self-care for Prostate Cancer Patients
Official Title
Benefits of an Intervention Combining Hypnosis and Self-care for Prostate Cancer Patients
Study Type
Interventional
2. Study Status
Record Verification Date
February 2018
Overall Recruitment Status
Completed
Study Start Date
October 14, 2013 (Actual)
Primary Completion Date
June 15, 2016 (Actual)
Study Completion Date
June 15, 2016 (Actual)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Principal Investigator
Name of the Sponsor
University of Liege
Collaborators
Free University of Brussels
4. Oversight
Studies a U.S. FDA-regulated Drug Product
No
Studies a U.S. FDA-regulated Device Product
No
Data Monitoring Committee
No
5. Study Description
Brief Summary
This study aims to assess the impact of a group intervention combining self-hypnosis and self-care techniques on prostate patients' well-being. More specifically, the investigators want to investigate the effects of that intervention on sleep, fatigue and emotional distress of the patients.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Prostate Cancer
7. Study Design
Primary Purpose
Supportive Care
Study Phase
Not Applicable
Interventional Study Model
Parallel Assignment
Model Description
Participants who agree to participate in the intervention are assigned in the experimental group, whereas participants who do not agree to participate in the intervention, but agree to answer the questionnaires, are assigned in the control group
Masking
None (Open Label)
Allocation
Non-Randomized
Enrollment
46 (Actual)
8. Arms, Groups, and Interventions
Arm Title
Intervention group : hypnosis + self-care
Arm Type
Experimental
Arm Description
Groupal intervention combining self-care techniques and self-hypnosis exercises
Arm Title
Control group : no intervention
Arm Type
No Intervention
Arm Description
Control group receiving usual care but not the intervention
Intervention Type
Behavioral
Intervention Name(s)
Self-hypnosis + Self-care
Intervention Description
Our groupal intervention is divided into 6 monthly 2-hour sessions in which one self-hypnosis exercise is proposed to participants. Self-care techniques are also discussed (knowing our own needs, selfrespect, assertiveness, coping with ruminations...) and homework assignments are proposed to participants, in order to foster positive change.
Primary Outcome Measure Information:
Title
Change in Fatigue
Description
A sense of tiredness or exhaustion linked with cancer and its treatments, that is not alleviated by sleep. Measured by the European Organization for Research and Treatment of Cancer - Quality of Life Core Questionnaire-30 (EORTC-QLCQ30). One symptom-related scale (fatigue, score based on 3 items, varies from 0 to 100, 100 being the worst fatigue endured) and the global health status (2 items, score varies from 0 to 100, 100 being the best quality of life) are used in this study.
Time Frame
T0 (before the intervention) and T1 (after the intervention : 6 months later).
Title
Change in emotional distress
Description
Anxiety + Depression, measured with the Hospital Anxiety and Depression Scale (HADS). Scores range (total): 0-42 (0-14: absence of anxio-depressive disorder ; 15-42: presence of anxio-depressive disorder). Two scales: anxiety and depression. For each, scores range 0-21 (0-7: absence of anxious or depressive disorder; 8-10: possibility of an anxious or depressive disorder; 11-21: presence of anxious or depressive disorder).
Time Frame
T0 (before the intervention) and T1 (after the intervention : 6 months later).
Title
Change in sleep difficulties
Description
Sleep difficulties (difficulties to stay asleep, to fall asleep...) and their severity. Measured by the Insomnia Severity Index. One score is calculated and ranges from 0 to 22 (0-7: absence of insomnia; 8-14: subclinical insomnia; 15-21: moderate insomnia; 22-28: severe insomnia).
Time Frame
T0 (before the intervention) and T1 (after the intervention : 6 months later).
10. Eligibility
Sex
Male
Minimum Age & Unit of Time
18 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria:
18-years-old,
ability to read, write and speak French
prostate cancer diagnosis
treatment with surgery and/or radiotherapy.
Exclusion Criteria:
metastases
cancer recurrence at the moment of inclusion
major cognitive or psychiatric disorder.
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Marie-Elisabeth Faymonville
Organizational Affiliation
University of Liege
Official's Role
Study Director
12. IPD Sharing Statement
Plan to Share IPD
No
Citations:
PubMed Identifier
29929493
Citation
Gregoire C, Nicolas H, Bragard I, Delevallez F, Merckaert I, Razavi D, Waltregny D, Faymonville ME, Vanhaudenhuyse A. Efficacy of a hypnosis-based intervention to improve well-being during cancer: a comparison between prostate and breast cancer patients. BMC Cancer. 2018 Jun 22;18(1):677. doi: 10.1186/s12885-018-4607-z.
Results Reference
derived
Learn more about this trial
Benefits of an Intervention Combining Hypnosis and Self-care for Prostate Cancer Patients
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