Biofeedback in Idiopathic Infantile Nystagmus Syndrome
Low Vision in Children
About this trial
This is an interventional treatment trial for Low Vision in Children focused on measuring biofeedback, vision rehabilitation, nystagmus, paediatric
Eligibility Criteria
Inclusion Criteria:
- Diagnosed as Infantile idiopathic nystagmus (IIN)
- Ability to follow the visual and auditory stimuli and training instructions
Exclusion Criteria:
- Ocular diseases not related to the nystagmus physiopathology
- Both eyes with media opacity that impairs microperimetry testing
- Peripheral nystagmus cases
- Other types of nystagmus than IIN
- Inability to perform during testing and training
Sites / Locations
- CNIBRecruiting
Arms of the Study
Arm 1
Arm 2
Active Comparator
Sham Comparator
Group A (treatment)
Group B (control)
Each session includes 20 minutes of training each with rest as needed. The procedure involves presentation of a standard LED fixation target (FT) consisting of a small red circle of about 0.76° diameter. A fixation training target (FTT) will be selected by the trainer at a perceived better fixation point. Initially the participant will be instructed to stare at the FT circle. Following this stage the participant will be guided to look in the direction of the FTT and listen simultaneously to the audio feedback. As performing this task, the participant will actively control the eye movements until the audio feedback becomes more frequent and then becomes a continuous sound pattern. This continuous sound will signalize to the patient that the FTT location was reached. Participants will be given take-home efficiency reading exercises.
The simulated biofeedback training for Group B involves the following procedure: For four weeks, presentation of a C10-2 microperimetry program. The procedure involves presentation of a standard LED fixation target (FT) consisting of a small red circle of about 0.76° diameter. Initially the participant will be instructed to stare at the FT circle. Following this stage the participant will be guided to look at the FT and simultaneously to be aware of any flashing lights in the periphery of vision. As performing this task, the participant will actively control the eye movements and similar to computer games, the patient has to identify targets in the peripheral field of vision and respond by pressing a button. Participants will be given take-home efficiency reading exercises.