Bladder Cancer Screening Trial
Bladder Cancer, Urothelial Carcinoma, Hematuria
About this trial
This is an interventional screening trial for Bladder Cancer
Eligibility Criteria
Inclusion Criteria: Age ≥ 50 Smoking: ≥15 pack-year smoking history Occupation:≥ 15 years of occupational exposures including: textile worker, painter, dry cleaners Exclusion Criteria: Prior history of bladder, kidney, or prostate cancer Prior evaluation of micro or gross hematuria within the last 2 years Do not provide informed consent
Sites / Locations
- University of Texas Southwestern Medical CenterRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
No Intervention
BCa Early Screening Group
Historical Control Group
All participants undergo Urinalysis testing every 6 months for 2 years. Based on the RBC count, each participant will go through each of the screening procedures : [cystoscopy + Upper tract imaging] or [urine marker cancer testing with Cxbladder triage + Upper tract imaging] or [Repeat urinalysis] Patients with suspicious findings on cystoscopy or imaging will get treatment as per standard of care. Their outcomes will be compared to a historical control (bladder cancer detected by standard of care using SEER registries).
This will include historical control (bladder cancer detected in patients by standard of care) using SEER registries).