Bryophyllum Pinnatum Treatment of Anxiety Related to Signs of Preterm Birth
Preterm Labor, Anxiety
About this trial
This is an interventional prevention trial for Preterm Labor focused on measuring Bryophyllum pinnatum, Anxiety, Preterm labor, Sleep quality, Phytotherapy
Eligibility Criteria
Inclusion Criteria:
- Single pregnancy
- At least 18 years old
- Stable clinical situation after complete tocolysis cycle of 48 h
- Gestational age at randomisation >28 weeks (28+0) and <34 weeks (33+6)
- Good German or English skills
- Written informed consent
Exclusion Criteria:
- Early premature rupture of the membranes (PPROM)
- Factors that make soon delivery likely (pre-eclampsia, suspect cardiotocography, clinical signs of an amniotic infection)
- Body temperature >38°C
- Cervical length < 10 mm at beginning of tocolysis
- Contraindication for B. pinnatum, lactose or wheat protein allergy
- Taking Bryophyllum 50% chewable tablets or powder 48 h before study inclusion
- Taking psychotropic drugs (Benzodiazepines, antidepressants, neuroleptics)
- Diagnosed psychiatric disease (depression, anxiety disorder, adaptation disorder, post- traumatic stress disorder, bipolar disorder)
- Active participation in another interventional study during the last 4 weeks
- Known or suspected non-compliance with study protocol
- Drug or alcohol abuse
Sites / Locations
- University Hospital ZurichRecruiting
Arms of the Study
Arm 1
Arm 2
Active Comparator
Placebo Comparator
Bryophyllum 50%
Placebo
Participants of the verum group take Bryophyllum 50% chewable tablets starting the day after study inclusion. Participants take 2 tablets, four times a day for 2 weeks. If the birth takes place before the end of the 2 weeks, the study participation is terminated early.
Participants of the control group take Placebo chewable tablets starting the day after study inclusion. Participants take 2 tablets, four times a day for 2 weeks. If the birth takes place before the end of the 2 weeks, the study participation is terminated early.