CA 125 Levels in Treating Patients With Relapsed Advanced Ovarian Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer Who Are Receiving Tamoxifen
Fallopian Tube Cancer, Ovarian Cancer, Primary Peritoneal Cavity Cancer
About this trial
This is an interventional diagnostic trial for Fallopian Tube Cancer focused on measuring stage IV ovarian epithelial cancer, recurrent ovarian epithelial cancer, stage IIIA ovarian epithelial cancer, stage IIIB ovarian epithelial cancer, stage IIIC ovarian epithelial cancer, recurrent fallopian tube cancer, stage IIIA fallopian tube cancer, stage IIIB fallopian tube cancer, stage IIIC fallopian tube cancer, stage IV fallopian tube cancer, recurrent primary peritoneal cavity cancer, stage IIIA primary peritoneal cavity cancer, stage IIIB primary peritoneal cavity cancer, stage IIIC primary peritoneal cavity cancer, stage IV primary peritoneal cavity cancer
Eligibility Criteria
DISEASE CHARACTERISTICS: Histologically confirmed advanced ovarian carcinoma, fallopian tube carcinoma, or primary peritoneal carcinoma Completed therapy for first relapse Had an elevated CA 125 level before starting relapse therapy with ≥ 50% fall by completion of that therapy or response according to RECIST criteria No significant cancer-related symptoms requiring urgent treatment PATIENT CHARACTERISTICS: ECOG performance status 0-2 Life expectancy > 3 months Hemoglobin > 10 g/dL WBC > 2,500/mm^3 Platelet count > 100,000/mm^3 Creatinine < 2 times upper limit of normal (ULN) AST/ALT < 2 times ULN Bilirubin < 1.5 times ULN No evidence of significant clinical disorder or laboratory finding that would preclude study participation No psychiatric disorder that would preclude informed consent Not pregnant or nursing PRIOR CONCURRENT THERAPY: No other concurrent hormonal therapy, except hormone-replacement therapy Other concurrent medications allowed provided dose is stable
Sites / Locations
- Queen's HospitalRecruiting
- Chelmsford and Essex CentreRecruiting
- Royal Derby HospitalRecruiting
- St. Luke's Cancer Centre at Royal Surrey County HospitalRecruiting
- Ipswich HospitalRecruiting
- Airedale General HospitalRecruiting
- Leeds Cancer Centre at St. James's University HospitalRecruiting
- Liverpool Women's HospitalRecruiting
- Saint Bartholomew's HospitalRecruiting
- Clatterbridge Centre for OncologyRecruiting
- Mount Vernon Cancer Centre at Mount Vernon HospitalRecruiting
- Kings Mill HospitalRecruiting
- Oxford Radcliffe HospitalRecruiting
- Wexham Park HospitalRecruiting
- Southampton General HospitalRecruiting
- Great Western HospitalRecruiting
- Hillingdon HospitalRecruiting
- NHS GrampianRecruiting
- Aberdeen Royal InfirmaryRecruiting
- North Glasgow University Hospitals NHS TrustRecruiting
- Ysbyty GwyneddRecruiting
- Velindre Cancer Center at Velindre HospitalRecruiting
- Glan Clwyd HospitalRecruiting
- Wrexham Maelor HospitalRecruiting