Can Additional Drug Therapy Accelerate Response Time to Antidepressants
Depression
About this trial
This is an interventional treatment trial for Depression focused on measuring depression
Eligibility Criteria
Inclusion Criteria: Patients, male and female, between the ages of 18 to 65 DSM-IV criteria for major depressive disorder No prior SSRI medication treatment (if a patient has discontinued a non-SSRI medication for side effects, they will not be excluded) Ability to be followed clinically for 6 weeks Each patient must understand the nature of the study and must sign an informed consent form Exclusion Criteria: Severe suicidality (as defined by Beck Depression Inventory Question 9, responses 2 or 3) Major Axis I mental illness other than major depressive disorder Unstable medical health specifically cardiovascular disease, abnormal EKG, history of severe drug allergy, poorly controlled diabetes, and asthma (pindolol contraindication) History of thyroid disease or abnormal TFT's (stage I or II) Need for adjunctive antipsychotic use or additional benzodiazepine during the study Pregnancy Seizure disorder A positive urine toxicology screen
Sites / Locations
- UCLA Neuropsychiatric Institute