Can Malnutrition be Prevented in Patient With Colorectal Cancer Stage Dukes D? (ColErn)
Primary Purpose
Colorectal Neoplasm
Status
Withdrawn
Phase
Not Applicable
Locations
Study Type
Interventional
Intervention
Individual dietary counseling.
Sponsored by
About this trial
This is an interventional supportive care trial for Colorectal Neoplasm focused on measuring Dietary intake, Dietary counseling, Weight loss, Body composition, Resting energy expenditure, Quality of life
Eligibility Criteria
Inclusion Criteria:
- metastatic colorectal cancer
- histological verified cancer
- age >18 years
Exclusion Criteria:
- cognitive reduction
- confusion
- not able to answer questionaire
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Arm Type
Active Comparator
No Intervention
Arm Label
Dietary counseling
Control
Arm Description
Patients receive dietary advice at an individual level and are offered contact with clinical dietitian every second week if necessary.
Outcomes
Primary Outcome Measures
Body weight
Secondary Outcome Measures
Body composition
Quality of life
Oncologic treatment
Dietary intake
Full Information
NCT ID
NCT00846313
First Posted
February 16, 2009
Last Updated
April 7, 2015
Sponsor
Norwegian University of Science and Technology
Collaborators
St. Olavs Hospital
1. Study Identification
Unique Protocol Identification Number
NCT00846313
Brief Title
Can Malnutrition be Prevented in Patient With Colorectal Cancer Stage Dukes D?
Acronym
ColErn
Official Title
A Randomised Study of Dietary Counseling for Patients With Colorectal Cancer.
Study Type
Interventional
2. Study Status
Record Verification Date
April 2015
Overall Recruitment Status
Withdrawn
Why Stopped
Study was stopped due to lack of resources (clinical dietitians)
Study Start Date
December 2003 (undefined)
Primary Completion Date
February 2009 (Actual)
Study Completion Date
February 2009 (Actual)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Sponsor
Name of the Sponsor
Norwegian University of Science and Technology
Collaborators
St. Olavs Hospital
4. Oversight
Data Monitoring Committee
No
5. Study Description
Brief Summary
The purpose of this randomised intervention study is to investigate to what degree patients with colorectal cancer benefit of dietary counselling regarding nutritional status, oncologic treatment and quality of life.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Colorectal Neoplasm
Keywords
Dietary intake, Dietary counseling, Weight loss, Body composition, Resting energy expenditure, Quality of life
7. Study Design
Primary Purpose
Supportive Care
Study Phase
Not Applicable
Interventional Study Model
Single Group Assignment
Masking
None (Open Label)
Allocation
Randomized
Enrollment
0 (Actual)
8. Arms, Groups, and Interventions
Arm Title
Dietary counseling
Arm Type
Active Comparator
Arm Description
Patients receive dietary advice at an individual level and are offered contact with clinical dietitian every second week if necessary.
Arm Title
Control
Arm Type
No Intervention
Intervention Type
Other
Intervention Name(s)
Individual dietary counseling.
Other Intervention Name(s)
Dietary intervention.
Intervention Description
Dietary advice based on individual requirement and symptom burden. Dietary intervention may be dietary advice, energy rich foods and drinks, oral nutritional supplements, appetite stimulation with Megestrol Acetate, enteral or parenteral nutrition.
Primary Outcome Measure Information:
Title
Body weight
Time Frame
2 year
Secondary Outcome Measure Information:
Title
Body composition
Time Frame
2 year
Title
Quality of life
Time Frame
2 years
Title
Oncologic treatment
Time Frame
2 years
Title
Dietary intake
Time Frame
2 years
10. Eligibility
Sex
All
Minimum Age & Unit of Time
18 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria:
metastatic colorectal cancer
histological verified cancer
age >18 years
Exclusion Criteria:
cognitive reduction
confusion
not able to answer questionaire
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Lene Thoresen, MSc
Organizational Affiliation
St. Olavs Hospital, NTNU
Official's Role
Principal Investigator
12. IPD Sharing Statement
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Can Malnutrition be Prevented in Patient With Colorectal Cancer Stage Dukes D?
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