Cardiac Strains for Optimization of CRT in Non-Responders
Chronic Heart Failure
About this trial
This is an interventional treatment trial for Chronic Heart Failure focused on measuring cardiac resynchronization therapy, non-responders
Eligibility Criteria
Inclusion Criteria:
- patients with symptomatic heart failure with NYHA III/IV, pharmacological treatment options exhausted, LVEF below 30%, and QRS duration over 130ms who did not respond to the implantation of CRT-D
Exclusion Criteria:
- Age below 18
- response to the original CRT implantation
Sites / Locations
- University Hospital Ostrava
Arms of the Study
Arm 1
Arm 2
Experimental
No Intervention
CRT-D re-programming
Control Group
The ineffective previously implanted CRT-D is reprogrammed under supervision of transthoracic echocardiography to: adjust the atrioventricular interval so that E and A waves do not overlap the interventricular interval is subsequently optimized to yield maximum improvement of the sum of longitudinal+radial+circumferential strains. Transthoracic echocardiography is performed prior to optimization and 3 months after optimization (i.e., 3 and 6 months after the CRT implantation) and and New York Heart Association Classification (NYHA Classification; total score range 1-4) is being determined in accordance with the standard NYHA methods re-programming of the interventricular interval
Only trans-thoracic echocardiography is performed during follow-ups at 3 and 6 months from CRT implantations performed and New York Heart Association Classification (NYHA Classification; total score range 1-4) is being determined in accordance with the standard NYHA methods