Catheter Ablation Therapy for Persistent Atrial Fibrillation (CLEAR-AF)
Persistent Atrial Fibrillation
About this trial
This is an interventional treatment trial for Persistent Atrial Fibrillation focused on measuring atrial fibrillation, catheter ablation
Eligibility Criteria
Inclusion Criteria:
- The main inclusion criterion is patients suffering from drug refractory persistent atrial fibrillation and referred to catheter ablation therapy. Persistent AF is defined as continuous AF for over 7 days, or lasting no more than 7 days but requiring pharmacological or electrical cardioversion.
Exclusion Criteria:
- Patients without spontaneous ongoing AF at the beginning of the procedure;
- Age: <18 years or >70 years;
- LA size > 55mm measured on echocardiogram;
- Previous AF ablation history including surgical ablation;
- Documented LA thrombus;
- Severe pulmonary diseases;
- Previous cardiac surgical history.
Sites / Locations
- China National Center for Cardiovascular DiseasesRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
With additional LAAW linear ablation
Without additional LAAW linear ablation
Patients who undergo CPVI+LA roof linear ablation+/ MI linear ablation, and additional LAAW linear ablation using ThermoCool SmartTouch catheter.
Patients who undergo CPVI+LA roof +/ MI linear ablation using ThermoCool SmartTouch catheter, without LAAW linear ablation.