Cerebello-Spinal tDCS as Rehabilitative Intervention in Neurodegenerative Ataxia (SCA02)
Ataxia, Spinocerebellar Ataxias, Spinocerebellar Ataxia Type 1
About this trial
This is an interventional treatment trial for Ataxia focused on measuring Transcranial direct current stimulation, Transcranial magnetic stimulation, Spinocerebellar ataxia, Cerebellar ataxia
Eligibility Criteria
Inclusion Criteria:
- Patients with a cerebellar syndrome and quantifiable cerebellar atrophy
Exclusion Criteria:
- Severe head trauma in the past
- History of seizures
- History of ischemic stroke or hemorrhage
- Pacemaker
- Metal implants in the head/neck region
- Severe comorbidity
- Intake of illegal drugs
- Pregnancy
Sites / Locations
- AO Spedali Civili
Arms of the Study
Arm 1
Arm 2
Experimental
Sham Comparator
Real tDCS - Real tDCS
Sham tDCS - Real tDCS
10 sessions of anodal cerebellar and cathodal spinal transcranial direct current stimulation (5 days/week for 2 weeks) followed by an open-label 10 sessions of anodal cerebellar and cathodal spinal transcranial direct current stimulation (5 days/week for 2 weeks)
10 sessions of sham cerebellar and sham spinal transcranial direct current stimulation (5 days/week for 2 weeks) followed by an open-label 10 sessions of anodal cerebellar and cathodal spinal transcranial direct current stimulation (5 days/week for 2 weeks).