Characterization of Breg Cells (Breg)
Healthy Volunteers, Arthritis, Rheumatoid
About this trial
This is an interventional basic science trial for Healthy Volunteers focused on measuring Regulatory B cells (Breg), Genes, Cell surface proteins, Nutrient transporters, Chemokine receptors
Eligibility Criteria
Inclusion Criteria:
- RA responding to ACR/EULAR 2010 criteria
Exclusion Criteria:
- steroid> 10 mg/d
- previous use of biological disease-modifying antirheumatic drug (DMARD)
- age<18 years
Sites / Locations
- Regional University Hospital
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Arm 5
Other
Other
Other
Other
Other
Nutrient transporters study
Chemokine receptors study
Genes study
Protein surface study
Protein surface & genes data validation
Blood sampling from 10 patients vith RA and 10 control patient for biological analysis and measure of nutrient transporters expression
Blood sampling from 10 patients vith RA and 10 control patient for biological analysis and measure of chemokine receptors expression
Blood sampling from 10 patients vith RA and 10 control patient for biological analysis and measure of genes expression
Blood sampling from 10 patients vith RA and 10 control patient for biological analysis and measure of protein surface expression
Blood sampling from 10 patients vith RA and 10 control patient for biological analysis and measure for validation of the data from "protein surface study" and "genes study" arms analysis.