Chemotherapy Followed by Surgery and Radiation Therapy With or Without Stem Cell Transplant in Treating Patients With Relapsed or Refractory Wilms' Tumor or Clear Cell Sarcoma of the Kidney
Kidney Cancer
About this trial
This is an interventional treatment trial for Kidney Cancer focused on measuring recurrent Wilms tumor and other childhood kidney tumors, clear cell sarcoma of the kidney
Eligibility Criteria
DISEASE CHARACTERISTICS: Diagnosis of Wilms' tumor or clear cell sarcoma of the kidney, meeting 1 of the following criteria: First relapse Refractory (progression during first-line therapy) Patients in second and subsequent relapses allowed if previously treated with vincristine, dactinomycin, and doxorubicin combination chemotherapy (VCR/DACT/DOX) Metachronous tumors in the contralateral kidney allowed if previously treated with VCR/DACT/DOX No rhabdoid tumor of the kidney Previously treated on UK Wilms' tumor study PATIENT CHARACTERISTICS: Age: Under 18 Performance status: Not specified Life expectancy: Not specified Hematopoietic: Not specified Hepatic: Not specified Renal: Not specified PRIOR CONCURRENT THERAPY: Biologic therapy Not specified Chemotherapy See Disease Characteristics Endocrine therapy Not specified Radiotherapy Not specified Surgery Not specified Other See Disease Characteristics
Sites / Locations
- Our Lady's Hospital for Sick Children Crumlin
- Birmingham Children's Hospital
- Bristol Royal Hospital for Children
- Addenbrooke's Hospital
- Leeds Cancer Centre at St. James's University Hospital
- Leicester Royal Infirmary
- Royal Liverpool Children's Hospital, Alder Hey
- Saint Bartholomew's Hospital
- Great Ormond Street Hospital for Children
- University College of London Hospitals
- Royal Manchester Children's Hospital
- Newcastle Upon Tyne Hospitals NHS Trust
- Queen's Medical Centre
- Oxford Radcliffe Hospital
- Children's Hospital - Sheffield
- Southampton General Hospital
- Royal Marsden - Surrey
- Royal Belfast Hospital for Sick Children
- Aberdeen Royal Infirmary
- Royal Hospital for Sick Children
- Royal Hospital for Sick Children