Chronic Pain Rehabilitation in Patients With Small Fiber Neuropathy
Small Fiber Neuropathy
About this trial
This is an interventional treatment trial for Small Fiber Neuropathy
Eligibility Criteria
Inclusion Criteria: Aged older than 18 years, Skin-biopsy proven idiopathic small fiber neuropathy (SFN), Main goal/purpose to achieve with rehabilitation therapy. Exclusion Criteria: Are not able to provide written informed consent, Have an underlying condition of SFN (diabetes, SCN (sodium voltage-gated channel alpha) 9A (subunit 9A) /10A (subunit 10A) /11A (subunit 11A) mutation, hypothyroidism, renal failure, vitamin B12 deficiency, monoclonal gammopathy of undetermined significance, alcohol abuses, malignancies, chemotherapeutic drugs), Have other neurological disease than SFN that may cause pain in the feet and/or damage to the somatosensory nervous system, are excluded, Have received any form of cognitive behavioral therapy within the last 6 months will be excluded from this study, Have insufficient comprehension of the Dutch language.
Sites / Locations
- Adelante ZorggroepRecruiting
- Maastricht University Medical CenterRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Active Comparator
Active Comparator
Active Comparator
Exposure in vivo-therapy
Graded activity-therapy
Acceptance and commitment therapy
In the first phase, patients with idiopathic small fiber neuropathy will receive exposure in vivo therapy for at least 4 weeks, 2 sessions/week. In the second phase, the therapy will be expanded with either 4 weeks or 6 weeks, 2sessions/week, depending on the outcome of the first session.
In the first phase, patients with idiopathic small fiber neuropathy will receive graded activity-therapy for at least 4 weeks, 2 sessions/week. In the second phase, the therapy will be expanded with either 4 weeks or 6 weeks, 2sessions/week, depending on the outcome of the first session.
In the first phase, patients with idiopathic small fiber neuropathy will receive acceptance and commitment therapy for at least 4 weeks, 2 sessions/week. In the second phase, the therapy will be expanded with either 4 weeks or 6 weeks, 2sessions/week, depending on the outcome of the first session.