Clinical and Basic Research on the Necessity of Scar Tissue Resection During Intrauterine Adhesions
Intrauterine Adhesion, Scar
About this trial
This is an interventional treatment trial for Intrauterine Adhesion
Eligibility Criteria
Inclusion Criteria:
- Consensus of Chinese Experts on the Clinical Diagnosis and Treatment of Intrauterine Adhesions, i.e., patients with previous history of induced abortion and other intrauterine operations, accompanied by periodical abdominal pain, fewmenorrhea, amenorrhea, recurrent abortion, infertility, and uterine adhesions found by hysteroscopy, who have fertility requirements;
- According to the American Reproductive Society prognostic classification, the AFS score was moderate to severe intrauterine adhesions, that is, the score range was 5-12 points;
- Patients ranged in age from 18 to 42 years old;
- normal endocrine function and ovulation;
- Patients had comprehensive clinical data and were followed up after surgery.
Exclusion Criteria:
- Patients with severe cardiovascular and cerebrovascular diseases, liver and kidney dysfunction and other systemic diseases;
- Patients who recently received female genital surgery or underwent high uterine flexion and were unable to receive hysteroscopy and surgical treatment;
- Amenorrhea, recurrent abortion and infertility caused by other factors such as neuro-endocrine system disorders or congenital abnormalities of reproductive structure and development;
- Patients with allergic reaction to estrogen and other drugs;
- Severe abnormal semen of the spouse.
Sites / Locations
- China, Shandong Qianfoshan HospitalRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
No Intervention
Intraoperative resection of intrauterine scar tissue by TCRA
No scar tissue resection group
Study group: patients took the bladder lithotomy position, routinely disinfected vulva and vagina, and laid sterile towel and sheet.pliers Clamp the front lip of the cervix, explore the depth of the uterine cavity, dilate the cervical canal one by one, place the endoscopy, and examine the uterine cavity.After the scar tissue contracted on one side, the scar tissue was disintegrated at the boundary between the intima and scar tissue. The scar tissue was removed with the annular electrode, and a balloon was placed after surgery to prevent re-adhesion.Complete adhesion release is defined as a return to normal shape of the uterine cavity with bilateral uterine angles exposed.
During the operation, the scar tissue covering the anterior, posterior and lateral walls of the uterine cavity was ploughed longitudinally into several narrow strips with needle-like electrodes, and scar tissue was not excised.