Clinical Effects of Pulsatile Insulin Delivery on Cognitive Function- Phase 1
Diabetes Mellitus
About this trial
This is an interventional treatment trial for Diabetes Mellitus focused on measuring Pulsatile intravenous insulin, Oral carbohydrate loading, Mindstream testing, Wechsler Memory Scale II, Respiratory Quotients, Hypoglycemia, Diabetes Mellitus with cognitive impairment, Diabetes Mellitus with complications
Eligibility Criteria
Inclusion Criteria: Inclusion Criteria: diagnosed with type 1 or type 2 diabetes mellitus. Self reporting or diagnosed with memory changes Taking oral agents and/or insulin for diabetic control Under Endocrinologist's supervision for diabetes management Endocrinologist must assess and approve patient for participation in this study Ability to swallow without difficulty Ability to commit to the weekly time requirements associated with the study Exclusion Criteria: Other causes of cognitive impairment not related to diabetes Inability to take cognitive testing Lack of intravenous access Pregnancy Alcohol abuse, drug addiction or the use of illegal drugs Positive HIV Inability to breathe into machine for respiratory quotients
Sites / Locations
- Florida Atlantic University
Arms of the Study
Arm 1
Experimental
1
Testing performed on diabetic patients with decline in cognitive function at baseline and quarterly after the start of receiving pulsatile intravenous insulin therapy to assess continuing cognitive function ability.