Cognitive-Behavioral Intervention for Worry, Uncertainty, and Insomnia for Cancer Survivors (FOCUS)
Anxiety Disorder, Worry, Uncertainty
About this trial
This is an interventional supportive care trial for Anxiety Disorder focused on measuring cancer, cancer survivors, worry, insomnia, symptoms, fatigue, depression, anxiety
Eligibility Criteria
Inclusion Criteria:
- lung cancer
- stage III or IV colorectal cancer
- pancreatic cancer
- esophageal cancer
- multiple myeloma
- leukemia
- stage IIIC and IV melanoma
- ovarian cancer
- stage III & IV cervical cancer
- stage III & IV uterine cancer
- stage IIIB, IIIC, and IV breast cancer
- glioblastoma multiforme
- early relapse (< 1 year) lymphoma
Exclusion Criteria:
- co-morbid immunologic disease (i.e. rheumatoid arthritis, systemic lupus)
- neurologic disease (i.e. multiple sclerosis, Parkinson's, Alzheimer's) that would affect neuro-immune assessment or completion of study questionnaires
- mania (if patient has bipolar disorder)
- active substance abuse disorders such as alcohol dependence and cocaine abuse will also be excluded
Sites / Locations
- Wexner Medical Center at The Ohio State University Department of Psychiatry
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Arm I (CBT for worry, uncertainty & insomnia)
Arm II (wait-list control)
Patients wear a wrist actigraph and complete a sleep diary and worry record daily in weeks 1 and 5. Patients participate in a Behavioral Intervention (cognitive-behavioral therapy) in which they receive education on the components of anxiety (physical cognitive, and behavioral) and practice relaxation techniques and behavioral sleep strategies in weeks 2-5.
Patients wear a wrist actigraph and complete a sleep diary and worry record daily in weeks 1 and 5. This is a wait-list comparison, so after six weeks, patients in the control group complete the behavioral (cognitive-behavioral therapy)intervention for worry, uncertainty, and insomnia.