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Cognitive Behavioral Therapy for Depression in Parkinson's Disease

Primary Purpose

Parkinson's Disease, Depression

Status
Terminated
Phase
Not Applicable
Locations
United States
Study Type
Interventional
Intervention
Cognitive Behavioral Therapy
Sponsored by
Oregon Health and Science University
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional supportive care trial for Parkinson's Disease focused on measuring Parkinson's disease, depression, Parkinson's disease with mild to moderate depression.

Eligibility Criteria

35 Years - 85 Years (Adult, Older Adult)All SexesDoes not accept healthy volunteers

Inclusion Criteria:

  • Parkinson's disease, mild to moderate depression, seen at Oregon Health & Science University

Exclusion Criteria:

  • Suicidal
  • Cognitive impairment with MOCA <26

Sites / Locations

  • Oregon Health & Science University

Arms of the Study

Arm 1

Arm Type

Experimental

Arm Label

1

Arm Description

All subjects in same investigative group with same CBT intervention.

Outcomes

Primary Outcome Measures

The change in CESD score

Secondary Outcome Measures

Full Information

First Posted
December 17, 2008
Last Updated
October 23, 2014
Sponsor
Oregon Health and Science University
Collaborators
National Parkinson Foundation
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1. Study Identification

Unique Protocol Identification Number
NCT00810628
Brief Title
Cognitive Behavioral Therapy for Depression in Parkinson's Disease
Official Title
Depression in Parkinson's Disease: A Pilot Project Using Cognitive Behavioral Therapy (CBT) to Improve Depression and Coping
Study Type
Interventional

2. Study Status

Record Verification Date
December 2008
Overall Recruitment Status
Terminated
Study Start Date
January 2009 (undefined)
Primary Completion Date
September 2009 (Actual)
Study Completion Date
December 2009 (Actual)

3. Sponsor/Collaborators

Name of the Sponsor
Oregon Health and Science University
Collaborators
National Parkinson Foundation

4. Oversight

Data Monitoring Committee
No

5. Study Description

Brief Summary
The purpose of this pilot program is to develop and evaluate a new treatment program for depression in Parkinson's disease (PD). The treatment uses Cognitive Behavior Therapy(CBT)to teach patients how to become more aware of their thoughts and feelings and to change thinking patterns and behaviors that may be related to depressive symptoms. This is the first time that this treatment has been used in a group setting for depression in PD. Target population is patients in the Movement Disorders Clinic at Oregon Health & Science University who have Parkinson's disease and mild to moderate depression.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Parkinson's Disease, Depression
Keywords
Parkinson's disease, depression, Parkinson's disease with mild to moderate depression.

7. Study Design

Primary Purpose
Supportive Care
Study Phase
Not Applicable
Interventional Study Model
Single Group Assignment
Masking
None (Open Label)
Allocation
N/A
Enrollment
12 (Actual)

8. Arms, Groups, and Interventions

Arm Title
1
Arm Type
Experimental
Arm Description
All subjects in same investigative group with same CBT intervention.
Intervention Type
Behavioral
Intervention Name(s)
Cognitive Behavioral Therapy
Intervention Description
Individual interviews and group discussion/training.
Primary Outcome Measure Information:
Title
The change in CESD score
Time Frame
Baseline and 10 weeks

10. Eligibility

Sex
All
Minimum Age & Unit of Time
35 Years
Maximum Age & Unit of Time
85 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria: Parkinson's disease, mild to moderate depression, seen at Oregon Health & Science University Exclusion Criteria: Suicidal Cognitive impairment with MOCA <26
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Julie H. Carter, MS
Organizational Affiliation
Oregon Health and Science University
Official's Role
Principal Investigator
First Name & Middle Initial & Last Name & Degree
Kristine Hanna, PhD
Organizational Affiliation
Oregon Health and Science University
Official's Role
Principal Investigator
Facility Information:
Facility Name
Oregon Health & Science University
City
Portland
State/Province
Oregon
ZIP/Postal Code
97239
Country
United States

12. IPD Sharing Statement

Citations:
PubMed Identifier
17377926
Citation
Dobkin RD, Allen LA, Menza M. Cognitive-behavioral therapy for depression in Parkinson's disease: a pilot study. Mov Disord. 2007 May 15;22(7):946-52. doi: 10.1002/mds.21455.
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Cognitive Behavioral Therapy for Depression in Parkinson's Disease

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